Abstract: A polyethylene glycol derivative compound is represented by Formula 1 described in the detailed description. In Formula 1, n is a natural number of 30 to 115, and R1 and R2 are C1 to C5 alkyl that are identical to or different from each other.

Abstract: Provided is a novel method for preparing a long-acting drug conjugate and a long-acting drug conjugate prepared using the method.

Abstract: Provided is a novel method for preparing a long-acting drug conjugate and a long-acting drug conjugate prepared using the method.

Abstract: A liquid formulation of a long-acting conjugate of a peptide having activities for a glucagon receptor and a GLP-1 receptor, and a method for preparing the liquid formulation are disclosed. The liquid formulation contains 18 nmol/mL to 940 nmol/mL of the long-acting conjugate, a buffering agent in an amount for maintaining the pH of the liquid formulation in the range of 4.5 to 7.5, and 1% (w/v) to 20% (w/v) of saccharide, and 0.001% (w/v) to 0.2% (w/v) of a nonionic surfactant.

Abstract: Provided is a novel method for preparing a long-acting drug conjugate and a long-acting drug conjugate prepared using the method.

Abstract: A method of preparing a protein conjugate contains linking a mono-PEGylated immunoglobulin Fc region to a dual agonist exhibiting activity on both GLP-1 and glucagon. The mono-PEGylated immunoglobulin Fc region is prepared by linking a linker of Formula 1 to the N-terminus of an immunoglobulin Fc region comprising a hinge sequence: CHO-L1-(OCH2CH2)nO-L2-R.

Abstract: Provided is a novel method for preparing a long-acting drug conjugate and a long-acting drug conjugate prepared using the method.

Abstract: An electronic device including an antenna is provided. The electronic device includes a first housing, a second housing for rotatably combining with the first housing, at least one hinge assembly configured to at least partially include an electric conductor portion, the at least one hinge assembly for rotatably coupling the second housing to the first housing, and at least one antenna device coupled to the at least one hinge assembly, in which the at least one antenna device includes a radiating conductor pattern and a ground patch, and the ground patch is electrically connected to the electric conductor portion of the at least one hinge assembly.

Abstract: A display device includes: a substrate on which a display area and a non-display area are defined; a plurality of pixels disposed on the substrate in the display area; and an encapsulation layer disposed on the pixels to cover the pixels, where the encapsulation layer including a first region and a second region different from the first region. The encapsulation layers has a thickness in a range of 1.75 ?m to 4.0 ?m, and the ratio of a thickness of the second region of the encapsulation layer to a thickness of the first region of the encapsulation layer is in a range of 0.95 to 1.0.

Abstract: Disclosed is an antenna device for an electronic device including a first housing and a second housing rotatably coupled to the first housing about a hinge axis. The antenna device may include: a radiation conductor disposed in the first housing; and a reflection member disposed adjacent to the radiation conductor in the first housing. Radio waves transceived by the radiation conductor are radiated via the reflection member. Also disclosed is an electronic device including the antenna device. The antenna device and the electronic device including the same may be variously implemented according to embodiments.

Abstract: A display device includes: a substrate on which a display area and a non-display area are defined; a plurality of pixels disposed on the substrate in the display area; and an encapsulation layer disposed on the pixels to cover the pixels, where the encapsulation layer including a first region and a second region different from the first region. The encapsulation layers has a thickness in a range of 1.75 ?m to 4.0 ?m, and the ratio of a thickness of the second region of the encapsulation layer to a thickness of the first region of the encapsulation layer is in a range of 0.95 to 1.0.

Abstract: An electronic device including an antenna is provided. The electronic device includes a first housing, a second housing for rotatably combining with the first housing, at least one hinge assembly configured to at least partially include an electric conductor portion, the at least one hinge assembly for rotatably coupling the second housing to the first housing, and at least one antenna device coupled to the at least one hinge assembly, in which the at least one antenna device includes a radiating conductor pattern and a ground patch, and the ground patch is electrically connected to the electric conductor portion of the at least one hinge assembly.

Abstract: Disclosed is an antenna device for an electronic device including a first housing and a second housing rotatably coupled to the first housing about a hinge axis. The antenna device may include: a radiation conductor disposed in the first housing; and a reflection member disposed adjacent to the radiation conductor in the first housing. Radio waves transceived by the radiation conductor are radiated via the reflection member. Also disclosed is an electronic device including the antenna device. The antenna device and the electronic device including the same may be variously implemented according to embodiments.

Abstract: The present invention relates to a composition for preventing skin aging containing aloesin or a derivative thereof. The aloesin or the derivative thereof, according to the present invention reduces cytotoxicity and inhibits a MMP-1 level and increases PIP levels and procollagen type 1, in normal human dermal fibroblasts (NHDF) after ultraviolet irradiation, and thus is particularly effective for preventing or treating skin photoaging induced by ultraviolet irradiation.

Abstract: An organic light emitting diode (OLED) display includes a substrate including a central area and a peripheral area adjacent the central area and bent at the center thereof, a first central OLED disposed on the central area of the bent substrate and including a first central organic emission layer having a first central thickness, and a first surrounding OLED disposed on the peripheral area of the bent substrate and including a first surrounding organic emission layer having a first surrounding thickness.

Abstract: An organic light emitting diode (OLED) display includes a substrate including a central area and a peripheral area adjacent the central area and bent at the center thereof, a first central OLED disposed on the central area of the bent substrate and including a first central organic emission layer having a first central thickness, and a first surrounding OLED disposed on the peripheral area of the bent substrate and including a first surrounding organic emission layer having a first surrounding thickness.

Abstract: The present invention provides a liquid crystal display panel and a method of manufacturing the liquid crystal display panel capable of reducing or eliminating metal erosion in an area in which a conductive dot is formed. In some embodiments, a display panel comprises a common electrode formed on an upper substrate, a first electrode formed on a lower substrate opposing the upper substrate and configured to receive a common voltage, a conductive dot formed between the upper substrate and the lower substrate and positioned to supply the common electrode with the common voltage, an insulating layer having a contact hole exposing the first electrode, and a second electrode formed on the insulating layer to connect the conductive dot and the first electrode, wherein a cross sectional area of the conductive dot between the upper substrate and the lower substrate is greater than a cross sectional area of an opening of the contact hole.

Abstract: A liquid crystal display apparatus includes a lower substrate, an upper substrate and a liquid crystal layer interposed between the lower substrate and the upper substrate. The lower substrate includes a display part for displaying image and a driving part for providing the display part with a driving signal. The upper substrate includes a common electrode and an insulating member that electrically insulates the common electrode from the driving part. The insulating member has a lower dielectric constant than the liquid crystal layer. Thus, a parasitic capacitance between the driving part and the common electrode is reduced to prevent malfunction of the driving part, and a display quality is enhanced.

Abstract: A liquid crystal display apparatus includes a lower substrate, an upper substrate and a liquid crystal layer interposed between the lower substrate and the upper substrate. The lower substrate includes a display part for displaying image and a driving part for providing the display part with a driving signal. The upper substrate includes a common electrode and an insulating member that electrically insulates the common electrode from the driving part. The insulating member has a lower dielectric constant than the liquid crystal layer. Thus, a parasitic capacitance between the driving part and the common electrode is reduced to prevent malfunction of the driving part, and a display quality is enhanced.

Abstract: An array substrate includes a transparent substrate, an organic insulation layer, a pixel electrode, a reflective layer, a light blocking pattern and a switching part. The transparent substrate includes a reflective window that reflects an ambient light and a transmissive window that transmits an artificial light. The organic insulation layer disposed over the transparent substrate becomes thinner gradually at a boundary between the transmissive window and the reflective window. The pixel electrode is formed in the transmissive region. The reflective layer is disposed over the organic insulation layer of the reflective window. The light blocking pattern is disposed at the boundary between the transmissive and reflective windows to prevent a light leakage. The switching part is electrically connected to the pixel electrode to apply an image signal to the pixel electrode. Therefore, a light leakage occurring at boundary is prevented by the light blocking pattern.