Abstract: A self-circularization RNA construct that can be expressed in a DNA vector and simultaneously circularized through a self-targeting and splicing reaction to form a circRNA is disclosed. The circRNA can consist only of a gene of interest which can be a coding, non-coding, or a combination thereof. The gene of interest has the advantage of being able to rapidly express a peptide or protein. The formed circRNA has a circular structure and has a stable and high half-life because 5? and 3? ends are not exposed. Accordingly, functional RNA such as miRNA, anti-miRNA, siRNA, shRNA, aptamer, functional RNA for gene/RNA editing, ADAR (adenosine deaminase acting on the RNA)-recruiting RNA, mRNA vaccine, mRNA therapeutic agent, vaccine adjuvant, and CAR-T mRNA can be produced as a stable circRNA in cells.

Abstract: A display device includes a base substrate, a pixel defining layer disposed on the base substrate and including a first opening, a light emitting structure disposed in the first opening of the pixel defining layer, a thin film encapsulation layer disposed on the light emitting structure, a touch electrode disposed on the thin film encapsulation layer, an insulating pattern disposed on the touch electrode and including a second opening which overlaps the first opening, and a high refractive layer disposed on the insulating pattern, the high refractive layer including a plurality of grid patterns disposed on a top surface of the high refractive layer, and a refractive index higher than a refractive index of the insulating pattern.

Abstract: A light-emitting element includes a first semiconductor layer, a light-emitting layer disposed on the first semiconductor layer, a second semiconductor layer disposed on the light-emitting layer, a device electrode layer disposed on the second semiconductor layer, a reflective electrode layer disposed on the device electrode layer, an insulating film surrounding a side surface of the light-emitting layer, a side surface of the second semiconductor layer, and a side surface of the device electrode layer, and a reflective layer surrounding a side surface of the insulating film, wherein the side surface of the device electrode layer is aligned with a side surface of the reflective electrode layer.

Abstract: A passenger restraint system of a vehicle includes a passenger restraint article with an interface, and a locking device that secures the interface. In some embodiments, the vehicle includes a vertical channel that enables the locking device to travel up and down. The locking device may include a camera that enables the locking device to align with the interface, and once aligned, the locking device secures the interface. In additional or alternative embodiments, the locking device includes two C-bars and a biasing element that urges the locking device into an open position. When the passenger sits or leans against the opened C-bars, the force caused by the interface on the C-bars overcomes the force applied by the biasing element, urging the C-bars into a closed position. The locking device is then secured by engaging a locking bar that pushes against a surface of the C-bars.

Abstract: A passenger restraint system of a vehicle includes a passenger restraint article with an interface, and a locking device that secures the interface. In some embodiments, the vehicle includes a vertical channel that enables the locking device to travel up and down. The locking device may include a camera that enables the locking device to align with the interface, and once aligned, the locking device secures the interface. In additional or alternative embodiments, the locking device includes two C-bars and a biasing element that urges the locking device into an open position. When the passenger sits or leans against the opened C-bars, the force caused by the interface on the C-bars overcomes the force applied by the biasing element, urging the C-bars into a closed position. The locking device is then secured by engaging a locking bar that pushes against a surface of the C-bars.

Abstract: The present invention relates to an inhalation toxicity testing chamber device for nanoparticles having a plurality of concentrations. The present invention provides an inhalation toxicity testing chamber device for nanoparticles having a plurality of concentrations, which: can supply nanoparticles having different concentrations to particle exposure modules by stacking a plurality of particle exposure modules inside a single chamber housing and by allowing each particle exposure module so as to form an independent space from each other; can perform inhalation toxicity testing of nanoparticles having a plurality of concentrations through a single chamber housing by being capable of exposing the test animals put into each particle exposure module to nanoparticles having different concentrations; can easily perform inhalation toxicity tests of nanoparticles in a small scale laboratory etc.

Abstract: A ride vehicle includes a base configured to move through an attraction environment and a sphere engaging the base and further including one or more ride seats disposed within the sphere. The one or more ride seats are coupled to an upper surface of a platform disposed within the sphere. The ride vehicle also includes a sphere drive system of the base configured to engage with an external surface of the sphere to rotate the sphere relative to the base. The upper surface of the platform is configured to remain substantially horizontal while the sphere drive system rotates the sphere.

Abstract: A ride vehicle includes a base configured to move through an attraction environment and a sphere engaging the base and further including one or more ride seats disposed within the sphere. The one or more ride seats are coupled to an upper surface of a platform disposed within the sphere. The ride vehicle also includes a sphere drive system of the base configured to engage with an external surface of the sphere to rotate the sphere relative to the base. The upper surface of the platform is configured to remain substantially horizontal while the sphere drive system rotates the sphere.

Abstract: The present invention relates to an inhalation toxicity testing chamber device for nanoparticles having a plurality of concentrations. The present invention provides an inhalation toxicity testing chamber device for nanoparticles having a plurality of concentrations, which: can supply nanoparticles having different concentrations to particle exposure modules by stacking a plurality of particle exposure modules inside a single chamber housing and by allowing each particle exposure module so as to form an independent space from each other; can perform inhalation toxicity testing of nanoparticles having a plurality of concentrations through a single chamber housing by being capable of exposing the test animals put into each particle exposure module to nanoparticles having different concentrations; can easily perform inhalation toxicity tests of nanoparticles in a small scale laboratory etc.