Abstract: The present disclosure provides T-cell modulatory multimeric polypeptides that comprise an immunomodulatory polypeptide and that comprise an epitope-presenting Wilms tumor peptide. A T-cell modulatory multimeric polypeptide is useful for modulating the activity of a T cell, and for modulating an immune response in an individual.

Abstract: Provided is an antimicrobial dressing, which includes: a first cover member having a plurality of pores formed therein and contacting a wound; an antimicrobial membrane that is made by accumulating nanofibers containing a water-soluble polymer that is dissolved in an exudate secreted from the wound, a water-insoluble polymer, and an antimicrobial substance released due to dissolution of the water-soluble polymer, the antimicrobial membrane being laminated on the first cover member and having a plurality of pores formed therein; and a second cover member laminated on the antimicrobial membrane and having a plurality of pores formed therein and exposed to an external air.

Abstract: Provided is a powder cosmetic composition including a positive charge donor material for enhancing makeup skin adhesion and preventing staining. The powder cosmetic composition may provide an effect of excellent makeup skin adhesion by including a positive charge donor material of a specific combination, thereby exhibiting a significantly higher positive charge than when a single positive charge donor material is included.

Abstract: Provided is an integrated structure of an ion filter and a reservoir according to an embodiment of the present disclosure. An integrated structure of an ion filter and a reservoir includes a reservoir storing coolant for cooling a fuel cell stack, an ion filter located inside the reservoir, and a control valve located inside the reservoir to be opened or closed so that the coolant flows into the ion filter, in which the reservoir is divided into a first region in which the ion filter is located by opening or closing the control valve and a second region that is a space other than the first region, and the first region and the second region are connected by an air vent unit through which air passes.

Abstract: A scaffold for cell culture or tissue engineering is provided. The scaffold includes a fiber web having a three-dimensional network structure, which includes a biodegradable scaffold fiber. Therefore, a microenvironment suitable for migration, proliferation and differentiation of cells to be cultured is created, thereby improving a cell proliferation rate and cell viability. In addition, the scaffold may be easily removed from cells cultured therein without physical/chemical stimuli, and thus the cultured cells may be easily recovered, and is able to be grafted into the body while the cultured cells are included in the scaffold. Moreover, the cultured cells may be cultured to have a similar shape/structure to those of an actual animal body to make it more suitable to be applied in grafting into an in vitro experimental model or animal body.

Abstract: An oral care composition for alleviating dentin hyperesthesia is disclosed. The oral care composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K—Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine(S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.

Abstract: An exemplary embodiment of the present disclosure provides a pressure sensitive heating element including a front electrode and a foam including a conductive material attached to one or both surfaces of the front electrode, and a method for manufacturing the same.

Abstract: The present disclosure provides a novel serine protease variant.

Abstract: A display driving circuit and a display device including the same are provided. The display driving circuit includes a source driver which applies source data to a display panel, a power supply unit which receives an external voltage from a power module to generate an internal voltage and a logic unit which is supplied with the internal voltage to control the source driver, wherein the logic unit includes a voltage variable determination logic which determines whether a supply voltage including the internal voltage and the external voltage is changed, thereby generating a voltage variable signal, and a voltage control logic which receives the voltage variable signal to change the supply voltage.

Abstract: Provided are a microorganism of the genus Corynebacterium which produces a purine nucleotide, and a method of producing a purine nucleotide using the microorganism.

Abstract: Disclose is a dry adhesive patch comprising: a plurality of embossed pillars formed on a substrate; a hemi-spherical adsorbing cup defining a top portion of each pillar, wherein a hemi-spherical hole is defined in a top portion of the adsorbing cup and is exposed to an outside; and an annular extension extending radially from an outer perimeter of a distal end of each adsorbing cup.

Abstract: A toothpaste composition for alleviating dentin hyperesthesia is disclosed. The composition includes a peptide consisting of an amino acid sequence of the following Formula 1: K-Y-R1-R2-R3-R4-R5-R6-R7-R8??(Formula 1) wherein R1 is arginine (R), lysine (K) or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are arginine (R) or lysine (K), respectively; R6 is asparagine (N) or serine (S); and R7 and R8 are lysine (K) or tyrosine (Y), respectively.

Abstract: Provided are a novel peptide, a polynucleotide encoding the peptide, an expression vector including the polynucleotide, and a pharmaceutical composition including the peptide, a quasi-drug composition including the peptide, and a health functional food composition including the peptide.

Abstract: Provided is a heating patch. The heating patch includes: a flexible plate-shaped base substrate; an electrode portion including a pair of lead electrodes formed on at least one surface of the base substrate along a longitudinal direction to be spaced apart along a width direction of the base substrate, and a pair of branch electrodes extending from the lead electrodes along the width direction of the base substrate to be not electrically connected to each other and to be overlapped with each other; a heating portion including a conductive heating material disposed in an overlapped part between the branch electrodes which have a predetermined area and face each other to generate heat while conducting the pair of branch electrodes to each other; and a pair of cover members disposed on both sides of the base substrate to prevent the electrode portion and the heating portion from being exposed externally.

Abstract: The present invention relates to a highly efficient aptamer complex comprising a branched DNA and an aptamer, and a pharmaceutical use thereof. More specifically, the aptamer complex of the present invention relates to a highly efficient aptamer complex including a Y-shaped DNA as the branched DNA and using vascular endothelial growth factor (VEGF) as a target molecule. The aptamer complex of the present invention and a pharmaceutical composition comprising the same as an active ingredient are expected to be widely used in the medical field since the binding efficiency with the target molecule is more remarkable than that of the conventional aptamer.

Abstract: Provided is a dry cosmetic sheet including: a dry support formed of a mesh, the mesh being made of a woven silver yarn; and a dry membrane laminated on the support, the dry membrane being capable of being attached to a users skin, and the dry membrane being formed of a fiber web, the fiber web being formed of accumulated electrospun fibers, each of the electrospun fibers being formed of a single homogeneous mixture containing a water-soluble polymer, a water-insoluble polymer, and a functional material for skin care in a dry state, the functional material being capable of releasing from the fiber by dissolution of the water-soluble polymer when the dry cosmetic sheet is moisturized. Each of the electrospun fibers has a homogenous distribution of the water-soluble polymer, the water-insoluble polymer, and the functional material.

Abstract: A novel peptide and a composition including the peptide are disclosed. The composition may be a pharmaceutical composition, a quasi-drug composition, a dietary supplement, or a food composition. A polynucleotide encoding the peptide and an expression vector including the polynucleotide are also disclosed. The peptide promotes regeneration of hard tissue and is useful for treating dentin-dental pulp diseases or periodontal diseases.

Abstract: Provided are compositions including a CPNE4 protein or a polynucleotide encoding thereof, a pharmaceutical composition, a quasi-drug composition, a dietary supplement, and a health functional food composition. A method for preventing or treating dentin-dental disease or periodontal disease and a method and a method for promoting regeneration of hard tissue including dentin, bone and cementum, and/or pulp tissue are disclosed.

Abstract: A multilayer ceramic capacitor includes a ceramic body including a dielectric layer, a plurality of first and second internal electrodes disposed inside the ceramic body, exposed to the first and second surfaces, and having ends exposed to the third or fourth surface, and a first side margin portion and a second side margin portion disposed on side portions of the plurality of first and second internal electrodes exposed to the first and second surfaces. A ratio Db/Da satisfies 1.00 to 1.07, inclusive, where ‘Db’ is a distance, in a stacking direction of the dielectric layer, between both end points of respective edge regions of the first side margin portion and the second side margin portion, and ‘Da’ is a distance in a central region of the ceramic body in the stacking direction.

Abstract: A patch-type sensor module is provided. A patch-type sensor module according to one embodiment of the present invention comprises: a power supply unit electrically connected with a flexible circuit board; a sensing unit which is mounted on the flexible circuit board and includes a temperature sensor for measuring a user's body temperature; a communication unit which allows power to be supplied using a wake-up function, wherein a pairing with an external communication module is concurrently established when power is supplied, and information measured through the sensing unit is then transmitted to the external communication module; a control unit for controlling operations of the power supply unit, the sensing unit, and the communication unit; and a protection member for preventing the flexible circuit board, the power supply unit, the sensing unit, the communication unit, and the control unit from being exposed to the outside.