Patents by Inventor Ji Hyun OUM

Ji Hyun OUM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL-BASED METHOD FOR DETERMINING AN ACTIVITY OF BOTULINUM TOXIN
    Publication number: 20250044281
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Application
    Filed: October 24, 2024
    Publication date: February 6, 2025
    Applicant: Hugel Inc.
    Inventors: Chee Gun LEE, Ji Hyun Oum, Vijayakumar Ajay, Xiangai Gui
  • NOVEL NEURONAL CELL LINE FOR MEASURING TITER OF NEUROTOXIN
    Publication number: 20240218326
    Abstract: As botulinum toxin has recently been attempted as a therapeutic agent for various indications, the demand for botulinum toxin in the medical and cosmetic fields has rapidly increased. However, there is no stable and highly reproducible cell-based assay method for measuring the potency of botulinum toxin. Since botulinum toxin is a very potent neurotoxin protein, the development of highly specific and sensitive cells is particularly required for accurate cell-based measurement of the potency of botulinum toxin. A neuronal cell line with altered gene expression is disclosed. The transformed cell line has significantly increased sensitivity to botulinum toxin, and thus is expected to be very effectively used for cell-based determination of botulinum toxin activity or cell-based detection of botulinum toxin.
    Type: Application
    Filed: May 25, 2022
    Publication date: July 4, 2024
    Applicant: HUGEL INC.
    Inventors: Heesoo JEON, Yusun CHOI, Ji-Hyun OUM, Changki LEE, Donghoon OH, Changjin LEE, Sena KIM
  • CELL-BASED METHOD FOR DETERMINING AN ACTIVITY OF BOTULINUM TOXIN
    Publication number: 20240077470
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Application
    Filed: November 6, 2023
    Publication date: March 7, 2024
    Applicant: HUGEL INC.
    Inventors: Chee Gun LEE, Ji Hyun Oum, Vijayajumar Ajay, Xiangai Gui
  • Cell-based method for determining an activity of botulinum toxin
    Patent number: 11360081
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: June 14, 2022
    Assignee: HUGEL INC.
    Inventors: Chee Gun Lee, Ji Hyun Oum, Vijayakumar Ajay, Xiangai Gui
  • Liquid formulation containing botulinum toxin and stabilizing agent, and preparation method therefor
    Patent number: 11224640
    Abstract: The present invention relates to a liquid formulation containing botulinum toxin and stabilizing agent, and preparation method therefor. A liquid formulation containing botulinum toxin and stabilizing agent according to the present invention can be easily stored and distributed. It was proved a significant effect on the stabilization of botulinum toxin under suitable conditions according to the temperature and pH of the human body. Thus, it is expected that the pharmaceutical composition of the present invention will greatly contribute to the safe and convenient medical use of botulinum toxin.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: January 18, 2022
    Assignee: Hugel Inc.
    Inventors: Chee Gun Lee, Ji Hyun Oum
  • CELL-BASED METHOD FOR DETERMINING AN ACTIVITY OF BOTULINUM TOXIN
    Publication number: 20220003752
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Application
    Filed: September 22, 2021
    Publication date: January 6, 2022
    Applicant: HUGEL INC.
    Inventors: Chee Gun LEE, Ji Hyun OUM, Vijayakumar AJAY, Xiangai GUI
  • Cell-based method for determining an activity of botulinum toxin
    Patent number: 11169144
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: November 9, 2021
    Assignee: HUGEL, INC.
    Inventors: Chee Gun Lee, Ji Hyun Oum, Vijayakumar Ajay, Xiangai Gui
  • Liquid formulation containing botulinum toxin and stabilizing agent, and preparation method therefor
    Patent number: 11147860
    Abstract: The present invention relates to a liquid formulation containing botulinum toxin and stabilizing agent, and preparation method therefor. A liquid formulation containing botulinum toxin and stabilizing agent according to the present invention can be easily stored and distributed. It was proved a significant effect on the stabilization of botulinum toxin under suitable conditions according to the temperature and pH of the human body. Thus, it is expected that the pharmaceutical composition of the present invention will greatly contribute to the safe and convenient medical use of botulinum toxin.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: October 19, 2021
    Assignee: Hugel Inc.
    Inventors: Chee Gun Lee, Ji Hyun Oum
  • CELL-BASED METHOD FOR DETERMINING AN ACTIVITY OF BOTULINUM TOXIN
    Publication number: 20210063383
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Application
    Filed: September 23, 2020
    Publication date: March 4, 2021
    Applicant: HUGEL, INC.
    Inventors: Chee Gun LEE, Ji Hyun OUM, Vijayakumar AJAY, Xiangai GUI
  • Cell-based method for determining an activity of botulinum toxin
    Patent number: 10908148
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: February 2, 2021
    Assignee: HUGEL, INC.
    Inventors: Chee Gun Lee, Ji Hyun Oum, Vijayakumar Ajay, Xiangai Gui
  • LIQUID FORMULATION CONTAINING BOTULINUM TOXIN AND STABILIZING AGENT, AND PREPARATION METHOD THEREFOR
    Publication number: 20200405828
    Abstract: The present invention relates to a liquid formulation containing botulinum toxin and stabilizing agent, and preparation method therefor. A liquid formulation containing botulinum toxin and stabilizing agent according to the present invention can be easily stored and distributed. It was proved a significant effect on the stabilization of botulinum toxin under suitable conditions according to the temperature and pH of the human body. Thus, it is expected that the pharmaceutical composition of the present invention will greatly contribute to the safe and convenient medical use of botulinum toxin.
    Type: Application
    Filed: July 21, 2020
    Publication date: December 31, 2020
    Applicant: Hugel Inc.
    Inventors: Chee Gun LEE, Ji Hyun OUM
  • LIQUID FORMULATION CONTAINING BOTULINUM TOXIN AND STABILIZING AGENT, AND PREPARATION METHOD THEREFOR
    Publication number: 20200405827
    Abstract: The present invention relates to a liquid formulation containing botulinum toxin and stabilizing agent, and preparation method therefor. A liquid formulation containing botulinum toxin and stabilizing agent according to the present invention can be easily stored and distributed. It was proved a significant effect on the stabilization of botulinum toxin under suitable conditions according to the temperature and pH of the human body. Thus, it is expected that the pharmaceutical composition of the present invention will greatly contribute to the safe and convenient medical use of botulinum toxin.
    Type: Application
    Filed: July 21, 2020
    Publication date: December 31, 2020
    Applicant: Hugel Inc.
    Inventors: Chee Gun LEE, Ji Hyun OUM
  • Cell-based method for determining an activity of botulinum toxin
    Patent number: 10866232
    Abstract: Anew cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: December 15, 2020
    Assignee: HUGEL, INC.
    Inventors: Chee Gun Lee, Ji Hyun Oum, Vijayakumar Ajay, Xiangai Gui
  • Cell-based method for determining an activity of botulinum toxin
    Patent number: 10823725
    Abstract: The present invention relates to a cell and an antibody for determining the activity of botulinum toxin, and a method of determining the activity of botulinum toxin using the same.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: November 3, 2020
    Assignee: HUGEL, INC.
    Inventors: Chee Gun Lee, Ji Hyun Oum, Vijayakumar Ajay, Xiangai Gui
  • CELL -BASED METHOD FOR DETERMINING AN ACTIVITY OF BOTULINUM TOXIN
    Publication number: 20200340979
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Application
    Filed: May 12, 2020
    Publication date: October 29, 2020
    Applicant: ABBIO INC.,
    Inventors: Chee Gun LEE, Ji Hyun OUM, Vijayakumar AJAY, Xiangai GUI
  • CELL -BASED METHOD FOR DETERMINING AN ACTIVITY OF BOTULINUM TOXIN
    Publication number: 20200340978
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Application
    Filed: May 12, 2020
    Publication date: October 29, 2020
    Applicant: ABBIO INC.,
    Inventors: Chee Gun LEE, Ji Hyun OUM, Vijayakumar AJAY, Xiangai GUI
  • CELL-BASED METHOD FOR DETERMINING AN ACTIVITY OF BOTULINUM TOXIN
    Publication number: 20200333325
    Abstract: A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.
    Type: Application
    Filed: May 12, 2020
    Publication date: October 22, 2020
    Applicant: ABBIO INC.,
    Inventors: Chee Gun LEE, Ji Hyun OUM, Vijayakumar AJAY, Xiangai GUI
  • Liquid formulation containing botulinum toxin and stabilizing agent, and preparation method therefor
    Patent number: 10772943
    Abstract: The present invention relates to a liquid formulation containing botulinum toxin and stabilizing agent, and preparation method therefor. A liquid formulation containing botulinum toxin and stabilizing agent according to the present invention be can be easily stored and distributed. It was proved a significant effect on the stabilization of botulinum toxin under suitable conditions according to the temperature and pH of the human body. Thus, it is expected that the pharmaceutical composition of the present invention will greatly contribute to the safe and convenient medical use of botulinum toxin.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: September 15, 2020
    Assignee: HUGEL INC.
    Inventors: Chee Gun Lee, Ji Hyun Oum
  • CELL-BASED METHOD FOR DETERMINING AN ACTIVITY OF BOTULINUM TOXIN
    Publication number: 20200173986
    Abstract: The present invention relates to a cell and an antibody for determining the activity of botulinum toxin, and a method of determining the activity of botulinum toxin using the same.
    Type: Application
    Filed: January 11, 2019
    Publication date: June 4, 2020
    Inventors: Chee Gun Lee, Ji Hyun Oum, Vijayakumar Ajay, Xiangai Gui
  • Liquid Formulation Containing Botulinum Toxin and Stabilizing Agent, and Preparation Method Therefor
    Publication number: 20190201506
    Abstract: The present invention relates to a liquid formulation containing botulinum toxin and stabilizing agent, and preparation method therefor. A liquid formulation containing botulinum toxin and stabilizing agent according to the present invention be can easily store and distribute. AND it was proved a significant effect on the stabilization of botulinum toxin under suitable conditions according to the temperature and pH of the human body. Thus, it is expected that the pharmaceutical composition of the present invention will greatly contribute to the safe and convenient medical use of botulinum toxin.
    Type: Application
    Filed: August 28, 2017
    Publication date: July 4, 2019
    Inventors: Chee Gun LEE, Ji Hyun OUM