Abstract: The present invention relates to a 6-6 bicyclic ring-containing compound derivative and use thereof. The compound according to the present invention acts as a PRMT5 inhibitor, and thus can be effectively used in the prevention or treatment of diseases caused by PRMT5.

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

Abstract: A power software development platform may include a platform adapter configured to provide a connection environment for a plurality of communication devices each installed in a plurality of power facilities, a platform gateway configured to collect data through a plurality of power systems to which the plurality of communication devices are connected, a platform interface which provide a distribution service for the data collected by the platform gateway, a platform data hub configured to receive the data through the distribution service, verify the received data, and provide an access environment for the verified data to an application developer, an analysis abstraction service configured to convert a plurality of physical analysis engines into abstracted services and provide the abstracted services to the application developer, and an application gateway configured to receive an application from the application developer and provide the application to an application user.

Abstract: A portable electronic device comprises a double-sided display including a first display side and a second display side formed on a side opposite the first display side; a direct memory access (DMA) controller configured to read first image data from a memory; at least one sensor configured to detect at least one of a position change of the double-sided display and a movement of a user's pupil and to output a detection signal; a status signal generator configured to interpret the detection signal output and to output a status signal; a transmission order determiner configured to receive the first image data from the DMA controller, to determine a transmission order of the first image data based on the status signal, and to output second image data corresponding to the determined transmission order; and a display driver integrated circuit (IC) configured to transmit the second image data to the display.

Abstract: A method of diagnosis based on biomarker and apparatus for performing the method includes receiving, by a diagnosis server, digital biomarker data from user equipment, generating, by the diagnosis server, basic diagnostic data on the basis of the digital biomarker data and generating, by the diagnosis server, diagnostic result data on the basis of the basic diagnostic data.

Abstract: A method of controlling user equipment for a medical checkup and an apparatus for performing the method include controlling user equipment for a medical checkup the includes generating digital biomarker control data by a diagnosis server on the basis of prescription data, and transmitting the digital biomarker control data to user equipment by the diagnosis server, wherein the digital biomarker control data includes information for controlling a digital biomarker module of the user equipment.

Abstract: An in-vehicle control apparatus which executes various functions of a vehicle and a method for controlling the same are provided. The in-vehicle operating apparatus includes an operating unit assembly and a drive unit that is configured to rotate the operating unit assembly about one axis. The operating unit assembly includes a body, a first operating unit disposed at a first side of the body and configured to receive a first command to execute at least a first function, and a second operating unit disposed at a second side of the body opposite to the first side of the body and configured to receive a second command to execute at least a second function.

Abstract: The present invention provides a composition for diagnosing fungal infection comprising 2-deoxy-2-[18F]fluorosorbitol ([18F]FDS) as an effective ingredient.

Abstract: A sphere-type shift control apparatus for an electronic transmission system includes a shift operation unit configured to be operated by a driver of a vehicle for gear shifting on a first hemisphere of a spherical mechanism and a design unit for indirect illumination and image transmission on a second hemisphere of the spherical mechanism. By rotating the spherical mechanism, only the shift operation unit is exposed to a vehicle interior through an opening of a housing when a shift operation is required, while only the design unit is exposed to the vehicle interior through the opening of the housing when the shift operation is not required.

Abstract: A power software development platform may include a platform adapter configured to provide a connection environment for a plurality of communication devices each installed in a plurality of power facilities, a platform gateway configured to collect data through a plurality of power systems to which the plurality of communication devices are connected, a platform interface which provide a distribution service for the data collected by the platform gateway, a platform data hub configured to receive the data through the distribution service, verify the received data, and provide an access environment for the verified data to an application developer, an analysis abstraction service configured to convert a plurality of physical analysis engines into abstracted services and provide the abstracted services to the application developer, and an application gateway configured to receive an application from the application developer and provide the application to an application user.

Abstract: Provided is an analytical method for providing information necessary for a diagnosis of alcohol use disorder, including measuring (i) an expression level of a gene encoding a JNK or p-JNK protein in a subject's sample, (ii) an expression level of a gene encoding a JNK or p-JNK protein and an expression level of a gene encoding the Elk-1 protein in a subject's sample, or (iii) expression levels of genes encoding JNK, p-JNK, and Elk-1 proteins in a subject's sample, respectively; and a kit for a diagnosis of alcohol use disorder which is used in the analytical method.

Abstract: The present invention relates to a composition for prevention or treatment of hypercortisolemia, the composition comprising allithiamine, fursultiamine, and benfotiamine, which are all derivatives of thiamine, or a mixed composition thereof. The composition for prevention or treatment of hypercortisolemia of the present invention can effectively treat or alleviate symptoms or disorders resulting from excessive secretion of cortisol, without surgical operations, and does not exhibit side effects caused by conventional medications.

Abstract: A fingerprint recognition vehicle control apparatus according to an embodiment of the present invention includes: a display unit including a hemispherical display, optical fibers provided in the display and connected to the display through one end of the optical fibers, and a light source connected to the other ends of the optical fibers; a fingerprint recognition unit including a fingerprint recognition sensor and a fingerprint pattern light source provided in the display unit; a gearshift including a physical wheel for operating gear stages and indicators indicating gear states; and a controller operating on the basis of information received from the display unit, the fingerprint recognition unit and the gearshift.

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

Abstract: The present invention relates to a mask. The mask includes: a body part covering respiratory organs of a user; and a hanging part provided at each of both sides of the body part to allow the body part to be fixed to the respiratory organs of the user. The body part includes a chin cover part of a chin part, which forms a lower portion and surrounds chin of the user.

Abstract: A multifunctional switch manipulator is provided. The manipulator includes a first switch unit, which is curved to be convex at the upper surface thereof, a second switch unit, which is disposed at a first side of the first switch unit and which extends radially in a first direction, and a third switch unit, which is disposed at a second side of the first switch unit and which extends radially in a second direction opposite the first direction. Each of the second and third switch units includes a housing that has an opening and a rotary knob disposed at the housing to be rotatable in a direction in which the opening extends, and at least one surface of the rotary knob is exposed to an outside through the opening.

Abstract: The present invention relates to a composition for eradicating Helicobacter pylori and a use thereof. The composition of the present invention maintains an intragastric pH at a certain level or more for a certain period of time or longer, thereby maximizing an action of amoxicillin and clarithromycin to show an excellent effect on eradicating Helicobacter pylori.

Abstract: A portable electronic device comprises a double-sided display including a first display side and a second display side formed on a side opposite the first display side; a direct memory access (DMA) controller configured to read first image data from a memory; at least one sensor configured to detect at least one of a position change of the double-sided display and a movement of a user's pupil and to output a detection signal; a status signal generator configured to interpret the detection signal output and to output a status signal; a transmission order determiner configured to receive the first image data from the DMA controller, to determine a transmission order of the first image data based on the status signal, and to output second image data corresponding to the determined transmission order; and a display driver integrated circuit (IC) configured to transmit the second image data to the display.