Abstract: The present invention provides a bionic organ device comprises a porous thermo-responsive layer, a cell culturing layer, a flow channel and a controlling module. The thermo-responsive layer is formed by weaving a fiber made of/from a plurality of thermo-responsive polymers and has a first surface and a second surface opposite to the first surface. The cell culturing layer is formed on the first surface of the thermo-responsive layer. The flow channel has an accommodating space for accommodating the thermo-responsive layer, wherein the flow channel is utilized to allow a flow passing through the second surface inside the flow channel. The controlling module is utilized to allow the flows having different flow temperatures passing through the second surface in the flow channel so as to control a temperature variation of the thermo-responsive layer around critical temperature whereby an expansion and contrast motion of the thermo-responsive layer can be generated.