Abstract: The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Abstract: Embodiments of the present disclosure provide a data mining system, a data mining method, and a storage medium. The data mining system includes a transfer device, a first trusted execution space and a second trusted execution space. The transfer device is configured to receive a data calling request of the second trusted execution space, obtain data to be called from the first trusted execution space according to the data calling request, and provide the data to be called to the second trusted execution space, so as to perform data mining based on the data to be called and the mining-related data to obtain a data mining result and to provide the data mining result to a device of the data user.

Abstract: The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Abstract: The present disclosure relates to at least one entity chosen from a compound of Formula (I), tautomers, stereoisomers or a mixture of stereoisomers, hydrates, and deuterated derivatives thereof, and pharmaceutically acceptable salts of any of the foregoing, and their use as epidermal growth factor receptor (EGFR) degraders for the prevention and treatment of diseases and conditions, e.g., cancer. The present disclosure also relates to pharmaceutical compositions containing such entities, and their use in treating or preventing a disease or disorder associated with EGFR.

Abstract: The present disclosure relates to novel glutarimide-containing compounds with KRAS mutant form degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of diseases and conditions.

Abstract: The present invention discloses a multi-tier wave-filter and an on-board power source DCDC conversion device. The multi-tier wave-filter includes: N-tiered PCB boards arranged at intervals, wherein N is greater than or equal to 3; N?1-level output inductors arranged at intervals, wherein an output inductor at each level is connected to adjacent upper-tier and lower-tier PCB boards through its input end and output end, respectively; N?1-level output capacitors arranged at intervals, wherein an output capacitor at each level is correspondingly connected to PCB boards between a second tier and a Nth tier, respectively; and a filter output terminal connected to an output end of the N?1-level output inductor. The multi-tier wave-filter provided by the present invention not only achieves miniaturizing the wave-filter and decreasing installation space, but also better enables the high-current path at the output end of the DCDC converter to have heat dissipation, filtering, shielding and other properties.

Abstract: The disclosure relates to a method, apparatus, readable medium, and electronic device for live stream interaction. The method includes: in accordance with displaying of a first control at a first target position of a live stream interface, obtaining a first duration during which a user watches the live stream interface; in accordance with a determination that the first duration is greater than or equal to a first predetermined duration threshold, switching the first control to a second control, and displaying the second control at a second target position of the live stream interface; and in response to a first operation command performed by the user on the second control, allocating a virtual resource to the user. In this way, interaction modes of a live stream room are enriched, and an activity level of the live stream room can be improved.

Abstract: The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Abstract: The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Abstract: Systems, apparatus, and methods for “fast” wake-up using virtualized addresses. Action cameras need to conserve power most of the time, but also be immediately responsive to catch action when it happens. Unfortunately, most general-purpose operating systems (e.g., Linux-based) lock up the processor during boot-up. Empirically, an OS boot process might take between 6-7 seconds from start to finish, even in highly streamlined boot sequences. This is undesirable, especially where one device (e.g., a smart phone) triggers an action camera to capture an image. Various embodiments of the present disclosure create “virtual action addresses” that directly expose interrupts as addressable space (via a Bluetooth Low Energy (BLE) network). In one such example, the interrupts trigger a capture or other action. The action camera can immediately service the interrupts with its real-time operating system (RTOS) while the general-purpose OS is booting up.

Abstract: The disclosure relates to a method, apparatus, readable medium, and electronic device for live stream interaction. The method includes: in accordance with displaying of a first control at a first target position of a live stream interface, obtaining a first duration during which a user watches the live stream interface; in accordance with a determination that the first duration is greater than or equal to a first predetermined duration threshold, switching the first control to a second control, and displaying the second control at a second target position of the live stream interface; and in response to a first operation command performed by the user on the second control, allocating a virtual resource to the user. In this way, interaction modes of a live stream room are enriched, and an activity level of the live stream room can be improved.

Abstract: A control method of a multi-tube air conditioner includes acquiring an exhaust temperature of a compressor of the multi-tube air conditioner and an evaporation temperature of a target indoor unit of the multi-tube air conditioner in response to detecting the multi-tube air conditioner being in a target operation state, determining a target opening of an electronic expansion valve of the target indoor unit according to the exhaust temperature and the evaporation temperature, acquiring a condensation temperature of the multi-tube air conditioner, determining a minimum limited opening of the electronic expansion valve according to the condensation temperature and the exhaust temperature, and adjusting an opening of the electronic expansion valve according to the target opening and the minimum limited opening.

Abstract: The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Abstract: The present disclosure relates to novel glutarimide-containing compounds with KRAS mutant form degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of diseases and conditions.

Abstract: The present disclosure relates to novel quinolinone-8-carbonitrile based compounds, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions. The compounds disclosed herein exhibit androgen receptor degradation activity.

Abstract: Provided are an interaction method and apparatus in a live streaming room, and a device and a storage medium. The method comprises: in response to a trigger operation for a preset duet entry on a live streaming room page, jumping from the live streaming room page to a camera capture page, wherein a host portrait cutout corresponding to the live streaming room page is displayed on the camera capture page and a capture control is provided on the camera capture page acquiring multimedia information captured by a camera, in response to a trigger operation for the capture control on the camera capture page, wherein the multimedia information comprises an image or a video; and synthesizing the multimedia information with the host portrait cutout to obtain a duet multimedia product.

Abstract: Embodiments are provided for compilation of a quantum program. In some embodiments, a system can include a processor that executes computer-executable components stored in memory. The computer-executable components can include an identification component that selects a subgraph that is common among a first commutation directed acyclic graph (DAG) and a second commutation DAG. The subgraph has an upper-bound size that is greater than a threshold size. The first commutation DAG represents a first quantum circuit of a set of quantum circuits and the second commutation DAG represents a second quantum circuit of the set of quantum circuits. The computer-executable components also include a compilation component that compiles a quantum subcircuit corresponding to the subgraph. The computer-executable components further include a configuration component that replaces the quantum subcircuit in the first quantum circuit with the compiled quantum subcircuit.

Abstract: Provided are an interaction method and apparatus in a live streaming room, a device, and a storage medium. The method comprises: in response to a trigger operation for a preset drawing entry on a live streaming room page, jumping to a graphic drawing page from the live streaming room page, a drawing trajectory set for a preset object being displayed on the graphical drawing page; when a drawing stroke on the graphic drawing page is received, matching the drawing stroke with the drawing trajectory; and if it is determined that the drawing stroke is successfully matched with the drawing trajectory, displaying prompt information about successful participation in a preset activity, the preset activity and the preset drawing entry having a correspondence.

Abstract: The present disclosure relates to novel compounds that inhibit glucose-induced degradation-deficient (GID) E3 ligase, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.

Abstract: The disclosure relates to a method, apparatus, readable medium, and electronic device for live stream interaction. The method includes: in accordance with displaying of a first control at a first target position of a live stream interface, obtaining a first duration during which a user watches the live stream interface; in accordance with a determination that the first duration is greater than or equal to a first predetermined duration threshold, switching the first control to a second control, and displaying the second control at a second target position of the live stream interface; and in response to a first operation command performed by the user on the second control, allocating a virtual resource to the user. In this way, interaction modes of a live stream room are enriched, and an activity level of the live stream room can be improved.