Patents by Inventor Ji Oiu

Ji Oiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
    Patent number: 6083715
    Abstract: Disclosed are methods and compositions for producing heterologous disulfide bond containing polypeptides in bacterial cells. In preferred embodiments the methods involve co-expression of a prokaryotic disulfide isomerase, such as DsbC or DsbG and a gene encoding a recombinant eukaryotic polypeptide. Exemplary polypeptides disclosed include tissue plasminogen activator.
    Type: Grant
    Filed: June 9, 1997
    Date of Patent: July 4, 2000
    Assignees: Board of Regents, The University of Texas System, Genentech, Inc.
    Inventors: George Georgiou, Ji Oiu, Paul Bessette, James Swartz