Patents by Inventor Ji-seong Yoon

Ji-seong Yoon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8716192
    Abstract: The present invention relates to a biomarker for the identification of exposure to lower aliphatic saturated aldehydes by using micro RNA and a method for the identification of exposure to lower aliphatic saturated aldehydes using the same. In this invention, the micro RNA at least 1.5 fold up-regulated by exposure to lower aliphatic saturated aldehydes and the micro RNA up to 0.66 fold down-regulated by the same were selected. These two micro RNAs can be effectively used as the biomarker for the monitoring of lower aliphatic saturated aldehydes and for the risk assessment thereby and at the same time as a tool to investigate the mechanism of toxicity caused by such lower aliphatic saturated aldehydes.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: May 6, 2014
    Assignee: Korea Institute of Science and Technology
    Inventors: Jae Chun Ryu, Mee Song, Ji-seong Yoon, Wooin Ryu, Hyo Sun Lee, Chan Young Shin
  • Publication number: 20130324429
    Abstract: The present invention relates to a biomarker for the identification of exposure to lower aliphatic saturated aldehydes by using micro RNA and a method for the identification of exposure to lower aliphatic saturated aldehydes using the same. In this invention, the micro RNA at least 1.5 fold up-regulated by exposure to lower aliphatic saturated aldehydes and the micro RNA up to 0.66 fold down-regulated by the same were selected. These two micro RNAs can be effectively used as the biomarker for the monitoring of lower aliphatic saturated aldehydes and for the risk assessment thereby and at the same time as a tool to investigate the mechanism of toxicity caused by such lower aliphatic saturated aldehydes.
    Type: Application
    Filed: November 29, 2012
    Publication date: December 5, 2013
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jae Chun Ryu, Mee Song, Ji-seong Yoon, Wooin Ryu, Hyo Sun Lee, Chan Young Shin
  • Publication number: 20130324428
    Abstract: The present invention relates to a biomarker for the identification of specific exposure to lower aliphatic saturated aldehydes which are volatile organic compounds exposed in the environment, and a method for the identification of specific exposure to lower aliphatic saturated aldehydes using the same, precisely a biomarker which is up- or down-regulated specifically by lower aliphatic saturated aldehyde exposure and a method for the identification of specific exposure to lower aliphatic saturated aldehydes using the biomarker. The biomarker of the present invention is the reacted genes selected by using DNA microarray chip, which can be effectively used for the monitoring and evaluation of lower aliphatic saturated aldehyde contamination in the environment samples and at the same time as a tool for the investigation of the toxic mechanism induced specifically by lower aliphatic saturated aldehydes.
    Type: Application
    Filed: November 29, 2012
    Publication date: December 5, 2013
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jae Chun Ryu, Mee Song, Ji-seong Yoon, Hyo Sun Lee, Wooin Ryu, Chan Young Shin
  • Publication number: 20130281311
    Abstract: The present invention relates to a biomarker for the identification of specific exposure to propionaldehyde which is one of volatile organic compounds exposed in the environment, and a method for the identification of specific exposure to propionaldehyde using the same, precisely a biomarker which is up-regulated or down-regulated specifically by propionaldehyde and a method for the identification of specific exposure to propionaldehyde using the biomarker. The biomarker of the present invention is the reacted genes selected by using DNA microarray chip, which can be effectively used for the monitoring and evaluation of propionaldehyde contamination in the environment samples and at the same time as a tool for the investigation of the toxic mechanism induced specifically by propionaldehyde.
    Type: Application
    Filed: November 29, 2012
    Publication date: October 24, 2013
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jae Chun Ryu, Mee Song, Ji-seong Yoon, Hyo Sun Lee, Wooin Ryu, Chan Young Shin