Abstract: The present invention relates to a method for stabilizing ceramide and to a cosmetic composition containing stabilized ceramide and, more specifically, to a method for homogenizing and stabilizing ceramide by self-assembling the ceramide together with ?-sitosterol, resveratrol, and allantoin which are other physiologically active substances using a microfluidic chip and a high pressure homogenizer, and to a technique for using ceramide and nanoparticles containing ?-sitosterol, resveratrol, and allantoin, which are produced by means of the stabilizing method, as a cosmetic material for skin moisturizing, anti-oxidation, skin inflammation relief, skin barrier enhancement, and skin itching relief.

Abstract: The present invention relates to a lipid-based nanoparticle composition for enhancing transdermal absorption and a method of preparing the same. The present invention provides a carrier for enhancing transdermal absorption that enhances or promotes chemical bonding with skin tissue by modifying the surface of lipid nanoparticles with a polyphenol. This may demonstrate the synergistic effect of active and passive transdermal delivery systems.

Abstract: The present invention relates to hybrid exosomes, a use of the same, and a preparation method of the same, and the hybrid exosomes provided from the present invention have excellent skin inflammation amelioration, skin wrinkle amelioration, skin moisturization efficacy, and skin regeneration efficacy compared to using hydrangea-derived exosomes and liposomes alone, and thus can be effectively utilized as a cosmetic composition containing the same as an active ingredient. In addition, the hybrid exosomes have better stability and biocompatibility compared to existing exosomes.

Abstract: The present invention provides a method for enabling a large integrated monitoring screen for integrated monitoring of multiple reactors, and a large integrated monitoring screen system. The method for enabling the large integrated monitoring screen comprises the steps of: a screen generation managing device in a remote integrated monitoring center generating at least one of a status monitoring screen, an early warning screen, a diagnostic analysis screen, and a CCTV screen with respect to a plurality of reactors in a nuclear power plant; and transmitting a screen requested by an administrator to the large integrated monitoring screen through an integrated screen control device.

Abstract: The present invention provides a method for diagnosing a rotation device by means of a rotor-bearing-foundation model, the method characterized by utilizing the characteristics of a simulation rotor system. To this end, the present invention comprises the steps of: simulating a rotation device as a rotor system; forming a mathematical model for the rotor system; estimating the state of the rotation device by means of the mathematical model and a vibration measurement value of the rotation device; and diagnosing for abnormalities in the rotation device from the changes in an estimated value. Therefore, since a rotation device is diagnosed for abnormalities by means of forming a mathematical model for a rotor system, the present invention enables more accurate diagnosis of the rotation device.