Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g.

Abstract: Disclosed herein is a device for interlocking a display device with a vehicle, the device including a mount disposed in the vehicle, the display device being attached to and detached from the mount, a first sliding member disposed on a front surface of the mount and capable of moving forward or backward in a direction perpendicular to a rear surface of the display device, and a connector provided to the first sliding member, wherein the connector may transmit and receive electrical signals to and from the display device. The vehicle may be controlled by coupling a display device to the interlocking device disposed in the vehicle. Even when the display device is not coupled to the vehicle, the vehicle may be controlled by pairing through wireless communication between the vehicle and the display device.

Abstract: A method for providing a healthcare program service over a wireless communication network includes receiving vital signals for a condition from measurement devices transmitted from multiple users and grouping the received vital signals, registering by a plurality of service providers corresponding healthcare programs classified by particular diseases, providing a healthcare program service to the multiple users, receiving feedback of use satisfaction for the healthcare programs from each user, counting the number of uses and gathering utilization information for each of the healthcare programs. The method further includes searching for a corresponding group of users using each healthcare program, adding up the user satisfactions and utilizations, databasing the results and upon receipt of vital signals for a condition from a particular user, comparing against similar signals and recommending a preferred healthcare program for a corresponding user group having vital signals for the condition.

Abstract: A home agent in a mobile Internet Protocol version 6 (IPv6) network system. The home agent is constructed with a home address table including home addresses of a plurality of mobile nodes and binding cache entry indexes corresponding to the home addresses, a next-hop entry table including a plurality of next hop entries mapped to care-of addresses of the mobile nodes, a binding cache entry table comprising a plurality of binding cache entries mapped to the binding cache entry indexes, and a packet processor. When a source address of a packet received by the home agent is included in the home address table in a state where forwarding direction information included in the packet received by the home agent differs from set forwarding direction information, the packet processor encapsulates and forwards the packet received by the home agent using a binding cache entry that is mapped to a binding cache entry index corresponding to the source address included in the home address table.

Abstract: A method for providing a healthcare program service in a system for providing a healthcare service over a wireless communication network includes: receiving vital signals for condition, measured by means of corresponding measurement devices, transmitted from multiple users over the wireless communication network, and grouping the received receiving vital signals for condition according to particular condition; registering by a plurality of service providers, corresponding healthcare programs classified by particular diseases, and providing a healthcare program service to the multiple users, receiving a feedback of a use satisfaction for each of the healthcare programs from each user via said wireless communication network, and gathering satisfaction information for each of the healthcare programs, counting the number of uses of each of the healthcare programs, and gathering utilization information for each of the healthcare programs, searching for a corresponding group of users using each of the healthcare pr

Abstract: A home agent in a mobile Internet Protocol version 6 (IPv6) network system. The home agent is constructed with a home address table including home addresses of a plurality of mobile nodes and binding cache entry indexes corresponding to the home addresses, a next-hop entry table including a plurality of next hop entries mapped to care-of addresses of the mobile nodes, a binding cache entry table comprising a plurality of binding cache entries mapped to the binding cache entry indexes, and a packet processor. When a source address of a packet received by the home agent is included in the home address table in a state where forwarding direction information included in the packet received by the home agent differs from set forwarding direction information, the packet processor encapsulates and forwards the packet received by the home agent using a binding cache entry that is mapped to a binding cache entry index corresponding to the source address included in the home address table.