Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.

Abstract: A lumbar support apparatus for a vehicle seat includes: a seatback frame having an adjustable inclination angle; an operating mechanism disposed at an upper portion of the seatback frame, the operating mechanism including a connector generating an operating force in a vertical direction by being in contact with a fixture fixed to a vehicle body when the inclination angle of the seatback frame is adjusted; and a support mechanism disposed at a lower portion of the seatback frame, connected to the connector, receiving the operating force generated from the connecting mechanism, and configured to slide in a front and rear direction depending on an application direction of the operating force, such that when the inclination angle of the seatback frame is adjusted to be directed rearward, the support mechanism receives the operating force of the operating mechanism and is advanced forward to support a waist of an occupant.

Abstract: An apparatus for providing drone data provides a method of matching a user who needs drone data of a certain area with at least one provider capable of providing drone data of a part or the entirety of the certain area.

Abstract: The present invention relates to a novel variant RNA polymerase sigma factor 70 (?70) polypeptide, a polynucleotide encoding the same, a microorganism containing the polypeptide, and a method for producing L-threonine by using the microorganism.

Abstract: Provided is a method for setting a thermal comfort scale of an age-specific perceived temperature of residents living in a certain area based on an experiment exposed to thermal stress environment in an artificial climate chamber.

Abstract: Disclosed is a method of operating a terminal on which an application for an instant messaging service is installed, the method that displays a first user interface (UI) for switching an input mode in a chatting interface of a chatroom in which a user of the application is participating, based on whether the user is assigned an authority to emphasize a message in the chatroom, switches the input mode from a first mode which is a normal mode to a second mode for emphasizing a message, in response to a user input with respect to the first UI, emphasizes a message input in the second mode for a predetermined period in a predetermined manner, and cancels the emphasizing of the message input in the second mode, when the predetermined time elapses.

Abstract: The present invention relates to a guanidine compound and a use thereof, and more specifically, to a guanidine derivative showing excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence; a preparation method thereof; and a pharmaceutical composition containing the same as an active ingredient. Compared to existing drugs, the guanidine derivative according to the present invention shows excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence even with small doses, and may thus be effectively used in preventing or treating various cancers such as uterine cancer, breast cancer, stomach cancer, brain cancer, rectal cancer, colorectal cancer, lung cancer, skin cancer, blood cancer, liver cancer, etc., inhibiting cancer cell proliferation and cancer metastasis.

Abstract: The present invention relates to a novel variant RNA polymerase sigma factor 70 (?70) polypeptide, a polynucleotide encoding the same, a microorganism containing the polypeptide, and a method for producing L-threonine by using the microorganism.

Abstract: An aspartokinase variant, a microorganism comprising the variant, and a method for producing an aspartate-derived L-amino acid or a homoserine derivative thereof using the microorganism.

Abstract: A lumbar support apparatus for a vehicle seat includes: a seatback frame having an adjustable inclination angle; an operating mechanism disposed at an upper portion of the seatback frame, the operating mechanism including a connector generating an operating force in a vertical direction by being in contact with a fixture fixed to a vehicle body when the inclination angle of the seatback frame is adjusted; and a support mechanism disposed at a lower portion of the seatback frame, connected to the connector, receiving the operating force generated from the connecting mechanism, and configured to slide in a front and rear direction depending on an application direction of the operating force, such that when the inclination angle of the seatback frame is adjusted to be directed rearward, the support mechanism receives the operating force of the operating mechanism and is advanced forward to support a waist of an occupant.

Abstract: An aspartokinase variant, a microorganism comprising the variant, and a method for producing an aspartate-derived L-amino acid or a homoserine derivative thereof using the microorganism.

Abstract: The present invention relates to a guanidine compound and a use thereof, and more specifically, to a guanidine derivative showing excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence; a preparation method thereof; and a pharmaceutical composition containing the same as an active ingredient. Compared to existing drugs, the guanidine derivative according to the present invention shows excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence even with small doses, and may thus be effectively used in preventing or treating various cancers such as uterine cancer, breast cancer, stomach cancer, brain cancer, rectal cancer, colorectal cancer, lung cancer, skin cancer, blood cancer, liver cancer, etc., inhibiting cancer cell proliferation and cancer metastasis.

Abstract: The present invention relates to guanidine compounds for inhibiting mitochondrial oxidative phosphorylation (OXPHOS) and use thereof. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating a OXPHOS-related disease, particularly cancer by inhibiting mitochondrial oxidative phosphorylation and reprogramming cellular metabolism.

Abstract: The present invention relates to a composition for dermal injection which includes two or more types of cross-linked hyaluronic acid particles having different particle diameters and non-cross-linked hyaluronic acid. The composition for dermal injection according to the present invention satisfies viscosity, extrusion force, and viscoelasticity conditions for dermal injection, and an extrusion force deviation is low so that the user does not feel fatigue when the composition is injected into the dermal thereof. Also, the composition is excellent in viscoelasticity and tissue restoring ability, is maintained for a long period of time, allows rapid recovery because an initial swelling degree is low, and also is excellent in safety and stability in the body.

Abstract: A nucleic acid molecule comprising a variant rpoC coding sequence is disclosed. The variant rpoC coding sequence encodes a variant RpoC which regulates copy number of a plasmid. Also disclosed are a recombinant microorganism comprising the nucleic acid molecule, a method for regulating copy number of a subject vector in the recombinant microorganism, and a method for making a target product by use of the recombinant microorganism.

Abstract: A nucleic acid molecule comprising a variant inc coding strand is disclosed as a regulator of plasmid copy number. Also disclosed is a replicon comprising the nucleic acid molecule, a promoter, and an origin of replication. Also disclosed is a vector comprising the replicon. Also disclosed is a recombinant microorganism comprising the vector.

Abstract: The present invention relates to a composition for dermal injection which includes two or more types of cross-linked hyaluronic acid particles having different particle diameters and non-cross-linked hyaluronic acid. The composition for dermal injection according to the present invention satisfies viscosity, extrusion force, and viscoelasticity conditions for dermal injection, and an extrusion force deviation is low so that the user does not feel fatigue when the composition is injected into the dermal thereof. Also, the composition is excellent in viscoelasticity and tissue restoring ability, is maintained for a long period of time, allows rapid recovery because an initial swelling degree is low, and also is excellent in safety and stability in the body.

Abstract: Disclosed is a method of operating a terminal on which an application for an instant messaging service is installed, the method that displays a first user interface (UI) for switching an input mode in a chatting interface of a chatroom in which a user of the application is participating, based on whether the user is assigned an authority to emphasize a message in the chatroom, switches the input mode from a first mode which is a normal mode to a second mode for emphasizing a message, in response to a user input with respect to the first UI, emphasizes a message input in the second mode for a predetermined period in a predetermined manner, and cancels the emphasizing of the message input in the second mode, when the predetermined time elapses.

Abstract: The present invention relates to a composition for dermal injection which includes two or more types of cross-linked hyaluronic acid particles having different particle diameters and non-cross-linked hyaluronic acid. The composition for dermal injection according to the present invention satisfies viscosity, extrusion force, and viscoelasticity conditions for dermal injection, and an extrusion force deviation is low so that the user does not feel fatigue when the composition is injected into the dermal thereof. Also, the composition is excellent in viscoelasticity and tissue restoring ability, is maintained for a long period of time, allows rapid recovery because an initial swelling degree is low, and also is excellent in safety and stability in the body.

Abstract: The present invention relates to a novel variant RNA polymerase sigma factor 70 (?70) polypeptide, a polynucleotide encoding the same, a microorganism containing the polypeptide, and a method for producing L-threonine by using the microorganism.