Abstract: The invention is to solve the high cost problems in the current health care system and to increase efficiency and quality of medical care service by using an integrated medical information management system. The invention allows users or patients to manage their own medical information worldwide in a portable device to enhance medication adherence and self-management of personalized health care. A multi-functional medical information center is developed to manage medical information received from various resources to satisfy stakeholders by improving the efficacy, accuracy, and quality of health care information, but simultaneously operated at a cost-effective manner for stakeholders. In addition, the quality control of medical data management will be guarded by a side-by-side comparison technology to warn inconsistent information in medical billing history to prevent medical insurance fraudulent claims.