Patents by Inventor Jia-Hao Xiao

Jia-Hao Xiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of screening for compounds that modulate hormone receptor activity
    Publication number: 20050130232
    Abstract: The present invention provides methods for identifying an effective agent that modulates a biological activity of a nuclear hormone receptor. In a method of the invention, an isolated receptor-containing complex is assayed for an altered modification state as compared to a control modification state. The presence of an altered modification state serves to identify an effective agent that modulates a biological activity of the nuclear hormone receptor.
    Type: Application
    Filed: August 20, 2004
    Publication date: June 16, 2005
    Applicant: Allergan, Inc.
    Inventors: Yi Zhao, Scott Thacher, Jia-Hao Xiao, Jyotirmoy Kusari, Roshantha Chandraratna
  • Methods and compositions for the treatment of cancer
    Publication number: 20040009921
    Abstract: Methods and compositions for treatment of cancer and other proliferative diseases comprising administration of RXR nuclear receptor protein and an agonist thereof. In other aspects, the present application is drawn to methods of screening compounds for RXR agonist activity comprising determining whether a test compound stimulates the degradation of B-catenin.
    Type: Application
    Filed: June 23, 2003
    Publication date: January 15, 2004
    Applicant: Allergan, Inc.
    Inventors: Jia-Hao Xiao, Corine Ghosn, Roshantha A. Chandraratna
  • Methods of screening for compounds that modulate hormone receptor activity
    Publication number: 20030077664
    Abstract: The present invention provides methods for identifying an effective agent that modulates a biological activity of a nuclear hormone receptor. In a method of the invention, an isolated receptor-containing complex is assayed for an altered modification state as compared to a control modification state. The presence of an altered modification state serves to identify an effective agent that modulates a biological activity of the nuclear hormone receptor.
    Type: Application
    Filed: August 2, 2001
    Publication date: April 24, 2003
    Inventors: Yi Zhao, Scott M. Thacher, Jia-Hao Xiao, Jyotirmoy Kusari, Roshantha A. Chandraratna