Patents by Inventor Jia-Hau SHIU

Jia-Hau SHIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion proteins for inhibiting angiogenesis
    Patent number: 11192927
    Abstract: The present invention relates to a biologic that inhibits angiogenesis. In particular, the present invention relates to fusion proteins that inhibit the integrin activated pathway and one other angiogenic factor-activated pathway, the compositions of these fusion proteins, as well as methods for producing and using the same.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: December 7, 2021
    Assignee: Allgenesis Biotherapeutics Inc.
    Inventors: Pei-Tzu Wu, Jia-Hau Shiu, Madhu Cherukury, Tan Nguyen, Kevin Zen
  • FUSION PROTEINS FOR INHIBITING ANGIOGENESIS
    Publication number: 20200181214
    Abstract: The present invention relates to a biologic that inhibits angiogenesis. In particular, the present invention relates to fusion proteins that inhibit the integrin activated pathway and one other angiogenic factor-activated pathway, the compositions of these fusion proteins, as well as methods for producing and using the same.
    Type: Application
    Filed: February 27, 2020
    Publication date: June 11, 2020
    Inventors: Pei-tzu WU, Jia-Hau SHIU, Madhu CHERUKURY, Tan NGUYEN, Kevin ZEN
  • EXPRESSION CONSTRUCT AND METHOD FOR PRODUCING PROTEINS OF INTEREST
    Publication number: 20190352365
    Abstract: Disclosed herein are expression constructs and methods for producing a protein of interest. According to some examples, an expression construct includes a nucleotide sequence encoding a fusion protein. To produce the protein of interest, the expression construct is transformed into a host cell, which is cultured under conditions that allow the expression of the fusion protein. The fusion protein has at least one expression unit; each expression unit has, sequentially, an affinity tag moiety, a spacer moiety, an enzymatic cleavage site, and a protein of interest moiety. The fusion protein is isolated from the host cell, solubilized, and refolded. The refolded fusion protein is cleaved to release the protein of interest.
    Type: Application
    Filed: January 18, 2018
    Publication date: November 21, 2019
    Applicant: Savior Lifetec Corporation
    Inventors: Shu-Ping YANG, Hong-Zhang WANG, Chi-Chao HU, Jia-Hau SHIU, Shih-Hsie PAN, Mannching Sherry KU
  • FUSION PROTEINS FOR INHIBITING ANGIOGENESIS
    Publication number: 20190194271
    Abstract: The present invention relates to a biologic that inhibits angiogenesis. In particular, the present invention relates to fusion proteins that inhibit the integrin activated pathway and one other angiogenic factor-activated pathway, the compositions of these fusion proteins, as well as methods for producing and using the same.
    Type: Application
    Filed: February 22, 2019
    Publication date: June 27, 2019
    Inventors: Pei-Tzu WU, Jia-Hau SHIU, Madhu CHERUKURY, Tan NGUYEN, Kevin Zen
  • FUSION PROTEINS FOR INHIBITING ANGIOGENESIS
    Publication number: 20180170979
    Abstract: The present invention relates to a biologic that inhibits angiogenesis. In particular, the present invention relates to fusion proteins that inhibit the integrin activated pathway and one other angiogenic factor-activated pathway, the compositions of these fusion proteins, as well as methods for producing and using the same.
    Type: Application
    Filed: June 24, 2016
    Publication date: June 21, 2018
    Inventors: Pei-Tzu WU, Jia-Hau SHIU, Madhu CHERUKURY, Tan NGUYEN, Kevin ZEN