Patents by Inventor Jia L. Wolfe

Jia L. Wolfe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HEREDITARY ANGIOEDEMA
    Publication number: 20230313227
    Abstract: Described herein are compositions and methods for treating a subject having or at risk of developing hereditary angioedema. Using the compositions and methods of the disclosure a patient may be provided one or more agents that elevate the expression and/or activity levels of C1-esterase inhibitor (C1-INH). Exemplary agents that may be used in conjunction with the compositions and methods of the disclosure for this purpose include cells, such as pluripotent cells, that express C1-INH.
    Type: Application
    Filed: August 13, 2021
    Publication date: October 5, 2023
    Inventors: Bobby GASPAR, Adrien LEMOINE, MSc, Jonathon Simeon MARKS-BLUTH, Jia L. WOLFE, Pervinder SAGOO, Valentina PENNUCCI
  • COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING CROHN'S DISEASE
    Publication number: 20220370509
    Abstract: Described herein are compositions and methods for treating a subject having or at risk of developing Crohn's disease. Using the compositions and methods of the disclosure, a patient, such as an adult human patient, may be provided one or more agents that elevate the expression and/or activity levels of Nucleotide-binding oligomerization domain-containing protein 2 (NOD2). Exemplary agents that may be used in conjunction with the compositions and methods of the disclosure for this purpose include cells, such as pluripotent cells, that express NOD2.
    Type: Application
    Filed: November 12, 2020
    Publication date: November 24, 2022
    Inventors: Bobby GASPAR, Jia L. WOLFE, Pervinder SAGOO
  • HPV specific oligonucleotides
    Publication number: 20030055240
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Application
    Filed: May 1, 2002
    Publication date: March 20, 2003
    Inventors: Peter C. Roberts, Bruce L. Frank, David E. Szymkowski, John S. Mills, John Goodchild, Jia L. Wolfe, Robert E. Kilkuskie, Isobel M. Greenfield, Veronica Sullivan
  • HPV-specific oligonucleotides
    Patent number: 6509149
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 21, 2003
    Assignee: Hybridon, Inc.
    Inventors: Peter C. Roberts, Bruce L. Frank, David E. Szymkowski, John S. Mills, John Goodchild, Jia L. Wolfe, Robert E. Kilkuskie, Isobel M. Greenfield, Veronica Sullivan
  • HPV-specific oligonucleotides
    Patent number: 6458940
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Grant
    Filed: July 2, 1997
    Date of Patent: October 1, 2002
    Assignee: Hybridon, Inc.
    Inventors: Peter C. Roberts, Bruce L. Frank, David E. Szymkowski, John S. Mills, John Goodchild, Jia L. Wolfe, Robert E. Kilkuskie, Isobel M. Greenfield, Veronica Sullivan
  • OLIGONUCLEOTIDES SPECIIFIC FOR HEPATITIS C VIRUS
    Publication number: 20020081577
    Abstract: The present invention discloses synthetic oligonucleotides complementary to contiguous and non-contiguous regions of the HCV RNA. Also disclosed are methods and kits for inhibiting the replication of HCV, inhibiting the expression of HCV nucleic acid and protein, and for treating HCV infections.
    Type: Application
    Filed: July 2, 1997
    Publication date: June 27, 2002
    Inventors: ROBERT L. KILKUSKIE, BRUCE L. FRANK, JOHN GOODCHILD, JIA L. WOLFE, PETER C. ROBERTS, HENRY A. HAMLIN, NOEL A. ROBERTS, DEBRA M. WALTHER
  • HPV-SPECIFIC OLIGONUCLEOTIDES
    Publication number: 20020068820
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Application
    Filed: June 6, 1995
    Publication date: June 6, 2002
    Inventors: PETER C. ROBERTS, BRUCE L. FRANK, DAVID E. SZYMKOWSKI, JOHN S. MILLS, JOHN GOODCHILD, JIA L. WOLFE, ROBERT E. KILKUSKIE, ISOBEL M. GREENFIELD, VERONICA SULLIVAN
  • HPV-SPECIFIC OLIGONUCLEOTIDES
    Publication number: 20010010899
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Application
    Filed: July 2, 1997
    Publication date: August 2, 2001
    Inventors: PETER C ROBERT, BRUCE L. FRANK, DAVID E. SZYMKOWSKI, JOHN S. MILLS, JOHN GOODCHILD, JIA L. WOLFE, ROBERT E. KILKUSKIE, ISOBEL M. GREENFIELD, VERONIA SULLIVAN