Patents by Inventor Jia L. Wolfe

Jia L. Wolfe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030055240
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Application
    Filed: May 1, 2002
    Publication date: March 20, 2003
    Inventors: Peter C. Roberts, Bruce L. Frank, David E. Szymkowski, John S. Mills, John Goodchild, Jia L. Wolfe, Robert E. Kilkuskie, Isobel M. Greenfield, Veronica Sullivan
  • Patent number: 6509149
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 21, 2003
    Assignee: Hybridon, Inc.
    Inventors: Peter C. Roberts, Bruce L. Frank, David E. Szymkowski, John S. Mills, John Goodchild, Jia L. Wolfe, Robert E. Kilkuskie, Isobel M. Greenfield, Veronica Sullivan
  • Patent number: 6458940
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Grant
    Filed: July 2, 1997
    Date of Patent: October 1, 2002
    Assignee: Hybridon, Inc.
    Inventors: Peter C. Roberts, Bruce L. Frank, David E. Szymkowski, John S. Mills, John Goodchild, Jia L. Wolfe, Robert E. Kilkuskie, Isobel M. Greenfield, Veronica Sullivan
  • Publication number: 20020081577
    Abstract: The present invention discloses synthetic oligonucleotides complementary to contiguous and non-contiguous regions of the HCV RNA. Also disclosed are methods and kits for inhibiting the replication of HCV, inhibiting the expression of HCV nucleic acid and protein, and for treating HCV infections.
    Type: Application
    Filed: July 2, 1997
    Publication date: June 27, 2002
    Inventors: ROBERT L. KILKUSKIE, BRUCE L. FRANK, JOHN GOODCHILD, JIA L. WOLFE, PETER C. ROBERTS, HENRY A. HAMLIN, NOEL A. ROBERTS, DEBRA M. WALTHER
  • Publication number: 20020068820
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Application
    Filed: June 6, 1995
    Publication date: June 6, 2002
    Inventors: PETER C. ROBERTS, BRUCE L. FRANK, DAVID E. SZYMKOWSKI, JOHN S. MILLS, JOHN GOODCHILD, JIA L. WOLFE, ROBERT E. KILKUSKIE, ISOBEL M. GREENFIELD, VERONICA SULLIVAN
  • Publication number: 20010010899
    Abstract: The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
    Type: Application
    Filed: July 2, 1997
    Publication date: August 2, 2001
    Inventors: PETER C ROBERT, BRUCE L. FRANK, DAVID E. SZYMKOWSKI, JOHN S. MILLS, JOHN GOODCHILD, JIA L. WOLFE, ROBERT E. KILKUSKIE, ISOBEL M. GREENFIELD, VERONIA SULLIVAN