Abstract: A degradable biomedical magnesium alloy drug-eluting vascular stent and a preparation method. With the total weight of a magnesium alloy being 100% for calculation, the magnesium alloy comprises the following components in percentage by weight: 3.0-6.0% of Gd, 2.5-5.5% of Y, 1.0-3.0% of Li, 0.3-1.0% of Zn, 0.2-1.0% of Zr, and the balance being Mg. The stent has good radial support strength and strain dispersion capability by means of finite element design. After a protective coating is used, the corrosion resistance of the magnesium alloy stent is greatly improved. An arsenic trioxide/rapamycin and tacrolimus composite drug sustained-release system is used to fully adapt to the damage repair process of blood vessels. An implantation result of large animals shows that the vascular stent system has a good anti-restenosis treatment effect.

Abstract: The invention belongs to magnesium alloy design field, and relates to a low-cost high-plasticity wrought magnesium alloy. The magnesium alloy is made from the raw materials with components as follows: between 0.10% and 1.00% by mass of tin, between 0.10% and 3.00% by mass of aluminum, between 0.10% and 1.00% by mass of manganese, and commercially pure magnesium and inevitable impurities in balance. The magnesium alloy is prepared by the steps of: melting magnesium and aluminum, adding tin and then adding microalloyed element manganese, stirring, refining, casting to form ingots followed by homogenized heat treatment, and extruding to obtain a corresponding profile; or directly extruding to obtain a corresponding profile without homogenization. The invention is characterized by controlling the content of the high-cost raw material tin through using the raw material aluminum that is low in cost and low in melting point to obtain a low-cost high-plasticity wrought magnesium alloy.