Patents by Inventor Jia Tay
Jia Tay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12178855Abstract: Provided herein are compositions and methods for facilitating or enhancing delivery of nucleic acids, such as synthetic mRNAs, into cells or tissues. Such compositions and methods may include use of a targeting moiety-conjugated, such as an N-acetylgalactosamine (GalNAc)-conjugated, oligonucleotide to facilitate or enhance delivery.Type: GrantFiled: January 10, 2019Date of Patent: December 31, 2024Assignee: Translate Bio MA, Inc.Inventors: Balkrishen Bhat, Jia Tay, Saswata Karmakar, Nelson Chau
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Publication number: 20240145163Abstract: A transformer includes a bobbin and a plurality of coils wound on the bobbin. The plurality of coils includes a first primary coil; a second primary coil, located above the first primary coil and electrically connected to the first primary coil; a secondary coil, located between the first primary coil and the second primary; a first auxiliary coil, located above the second primary coil; and a second auxiliary coil, located on the first auxiliary coil and electrically connected to the first auxiliary coil.Type: ApplicationFiled: October 20, 2023Publication date: May 2, 2024Inventors: Chiao FU, Yi-Chao LIN, Yao-Zhong LIU, Jia-Tay KUO
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Publication number: 20230275073Abstract: A package structure is provided herein, which includes a substrate, an integrated transistor, and an encapsulation structure. The integrated transistor is disposed on the substrate and includes a transistor, a capacitor, a resistor, a first Zener diode, and a second Zener diode. The transistor includes a gate, a drain, and a source. The capacitor is electrically connected to the gate, and the resistor is electrically connected to the gate. The first Zener diode includes a first anode and a first cathode electrically connected to the gate. The second Zener diode includes a second anode electrically connected to the first anode and a second cathode electrically connected to the source. The encapsulation structure encapsulates the integrated transistor. The package structure includes a gate terminal, a drain terminal, and a source terminal.Type: ApplicationFiled: February 24, 2023Publication date: August 31, 2023Inventors: Jia-Tay KUO, Chiao FU, Sheng-Bo WANG, Chen-Yu WANG, Yao-Zhong LIU
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Publication number: 20220218829Abstract: Provided herein are conjugates comprising targeting moieties such as sugars, folates and cell-penetrating peptides, which can be used for the improved delivery of agents (e.g., nucleic acids, such as oligonucleotides or mRNAs, or other agents) to cells. The invention provides conjugates and compounds comprising targeting moieties, methods for preparing the same, and intermediates useful in their preparation. In another aspect, the present invention provides formulations (e.g., pharmaceutical compositions) comprising the targeting moiety-containing conjugates and compounds. The present invention also provides methods for delivering agents (e.g., nucleic acids such as oligonucleotides or mRNAs) to a cell, methods for treating and/or preventing a disease or condition in a subject, and methods for modulating gene expression in a cell or a subject. Further, provided herein are kits comprising the conjugates, or formulations thereof; and kits for the preparation of conjugates described herein.Type: ApplicationFiled: December 16, 2021Publication date: July 14, 2022Applicant: Translate Bio MA, Inc.Inventors: Balkrishen Bhat, Saswata Karmakar, Debatosh Majumdar, Jia Tay, Nelson Chau
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Patent number: 11253601Abstract: Provided herein are conjugates comprising targeting moieties such as sugars, folates and cell-penetrating peptides, which can be used for the improved delivery of agents (e.g., nucleic acids, such as oligonucleotides or mRNAs, or other agents) to cells. The invention provides conjugates and compounds comprising targeting moieties, methods for preparing the same, and intermediates useful in their preparation. In another aspect, the present invention provides formulations (e.g., pharmaceutical compositions) comprising the targeting moiety-containing conjugates and compounds. The present invention also provides methods for delivering agents (e.g., nucleic acids such as oligonucleotides or mRNAs) to a cell, methods for treating and/or preventing a disease or condition in a subject, and methods for modulating gene expression in a cell or a subject. Further, provided herein are kits comprising the conjugates, or formulations thereof; and kits for the preparation of conjugates described herein.Type: GrantFiled: July 11, 2017Date of Patent: February 22, 2022Assignee: Translate Bio MA, Inc.Inventors: Balkrishen Bhat, Saswata Karmakar, Debatosh Majumdar, Jia Tay, Nelson Chau
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Publication number: 20210273138Abstract: The present application discloses a light-emitting device comprises a semiconductor light-emitting element, a transparent element covering the semiconductor light-emitting element, an insulating layer which connects to the transparent element, an intermediate layer which connects to the insulating layer; and a conductive adhesive material connecting to the intermediate layer.Type: ApplicationFiled: May 17, 2021Publication date: September 2, 2021Inventors: Chien-Liang LIU, Ming-Chi HSU, Shih-An LIAO, Jen-Chieh YU, Min-Hsun HSIEH, Jia-Tay KUO, Yu-His SUNG, Po-Chang CHEN
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Patent number: 11011681Abstract: The present application discloses a light-emitting device comprises a semiconductor light-emitting element, a transparent element covering the semiconductor light-emitting element, an insulating layer which connects to the transparent element, an intermediate layer which connects to the insulating layer; and a conductive adhesive material connecting to the intermediate layer.Type: GrantFiled: November 14, 2014Date of Patent: May 18, 2021Assignee: Epistar CorporationInventors: Chien-Liang Liu, Ming-Chi Hsu, Shih-An Liao, Jen-Chieh Yu, Min-Hsun Hsieh, Jia-Tay Kuo, Yu-His Sung, Po-Chang Chen
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Publication number: 20210052706Abstract: Provided herein are compositions and methods for facilitating or enhancing delivery of nucleic acids, such as synthetic mRNAs, into cells or tissues. Such compositions and methods may include use of a targeting moiety-conjugated, such as an N-acetylgalactosamine (GalNAc)-conjugated, oligonucleotide to facilitate or enhance delivery.Type: ApplicationFiled: January 10, 2019Publication date: February 25, 2021Applicant: Translate Bio MA, Inc.Inventors: Balkrishen Bhat, Jia Tay, Saswata Karmakar, Nelson Chau
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Patent number: 10412801Abstract: A light-emitting device includes a current source module having a first transistor, a first voltage control module providing a negative voltage and a second voltage control module having a second transistor. The second voltage control module is electrically connected to the current source module and the first voltage control module.Type: GrantFiled: August 23, 2018Date of Patent: September 10, 2019Assignee: EPISTAR CORPORATIONInventors: Chao-Kai Chang, Yi-Chao Lin, Chang-Hseih Wu, Jia-Tay Kuo
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Publication number: 20190224326Abstract: Provided herein are conjugates comprising targeting moieties such as sugars, folates and cell-penetrating peptides, which can be used for the improved delivery of agents (e.g., nucleic acids, such as oligonucleotides or mRNAs, or other agents) to cells. The invention provides conjugates and compounds comprising targeting moieties, methods for preparing the same, and intermediates useful in their preparation. In another aspect, the present invention provides formulations (e.g., pharmaceutical compositions) comprising the targeting moiety-containing conjugates and compounds. The present invention also provides methods for delivering agents (e.g., nucleic acids such as oligonucleotides or mRNAs) to a cell, methods for treating and/or preventing a disease or condition in a subject, and methods for modulating gene expression in a cell or a subject. Further, provided herein are kits comprising the conjugates, or formulations thereof; and kits for the preparation of conjugates described herein.Type: ApplicationFiled: July 11, 2017Publication date: July 25, 2019Applicant: Translate Bio MA, Inc.Inventors: Balkrishen Bhat, Saswata Karmakar, Debatosh Majumdar, Jia Tay, Nelson Chau
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Publication number: 20150129919Abstract: The present application discloses a light-emitting device comprises a semiconductor light-emitting element, a transparent element covering the semiconductor light-emitting element, an insulating layer which connects to the transparent element, an intermediate layer which connects to the insulating layer; and a conductive adhesive material connecting to the intermediate layer.Type: ApplicationFiled: November 14, 2014Publication date: May 14, 2015Inventors: Chien-Liang LIU, Ming-Chi HSU, Shih-An LIAO, Jen-Chieh YU, Min-Hsun HSIEH, Jia-Tay KUO, Yu-His SUNG, Po-Chang CHEN
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Patent number: D1059315Type: GrantFiled: April 27, 2023Date of Patent: January 28, 2025Assignee: GaNrich Semiconductor CorporationInventors: Jia-Tay Kuo, Chen-Yu Wang, Sheng-Bo Wang, Chiao Fu, Yao-Zhong Liu