Abstract: The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

Abstract: A layout dependent statistical leakage analyzing method includes providing pre-silicon data, acquiring an i-th pre-silicon leakage value of an i-th cell group according to the pre-silicon data, acquiring an (i,j)-th abutment possibility of a j-th cell group abutted on the i-th cell group according to physical information extracted from the pre-silicon data, acquiring an i-th scaling factor for a Silicon-to-SPICE (S2S) of the i-th cell group according to the pre-silicon data, acquiring an (i,j)-th layout dependent effect (LDE) factor between the i-th cell group and the j-th cell group according to the pre-silicon data and post-silicon data, and generating an estimated silicon leakage of a block according to N pre-silicon leakage values, N2 abutment possibilities, N scaling factors, and N2 LDE factors.

Abstract: The present disclosure provides compounds and compositions thereof which are useful as inhibitors of JAK2 and which exhibit desirable characteristics for the same.

Abstract: The present disclosure provides solid forms of a JAK2 inhibitor, as well as compositions thereof and methods of using and preparing the same.

Abstract: This disclosure describes methods, non-transitory computer readable storage media, and systems that provide secure password sharing across a plurality of users and client devices via a shared folder. For example, in one or more embodiments, the disclosed system retrieves a public key set including public encryption keys for client devices having access to the shared folder. The disclosed system provides the public key set to a client device requesting to share the shared folder. The disclosed system receives an encrypted payload for the shared folder and a shared encryption key that is utilized to encrypt the payload and is encrypted in the shared folder utilizing the public key set. The disclosed system also detects key rotation events and notifies one or more client devices to generate a modified shared encryption key and re-encrypt the payload for storage within the shared folder.

Abstract: The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

Abstract: A cold sensation presentation device includes: a cold stimulus section that contactlessly gives a cold stimulus to a skin; a warm stimulus section that contactlessly gives a warm stimulus to a skin; and a control unit that presents a cold sensation by causing a temporal change in the intensity of the cold stimulus in a cold stimulus state where the intensity of the warm stimulus is relatively small and a temporal change in the intensity of the warm stimulus in a warm stimulus state where the intensity of the warm stimulus is relatively large to be different from each other, and repeating the cold stimulus state and the warm stimulus state in a state of keeping the intensity of the cold stimulus constant.

Abstract: The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

Abstract: Described herein are compounds that are useful in treating a USP7-mediated disorder. In some embodiments, the USP7-mediated disorder is cancer.

Abstract: The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

Abstract: The present disclosure provides heterocyclic amide and urea compounds and compositions thereof useful for inhibiting JAK2.

Abstract: A heave survey platform includes: a body, two fixed wings and two variable wing mechanisms. The two fixed wings are symmetrically disposed on two sides of a middle part of the body, and an axis of the body is located in a plane defined by extension directions of the two fixed wings. Each variable wing mechanism includes a variable wing, and the two variable wings of the two variable wing mechanisms are symmetrically disposed on two sides of a lower end of the body, and each variable wing is configured to swing between a first position coplanar with the plane and a second position forming an angle with the plane to generate a lift force on the body at the second position, thereby to make the body move in a radial direction or change attitude.

Abstract: A driving method is implemented to a lifting device of an underwater survey system, and the lifting device includes a phase-change heat exchange module, an oil bag module, a pressurized energy storage module, and a drive energy storage module. The driving method includes: controlling the pressurized energy storage module to extract hydraulic oil in the oil bag module to descend the lifting device; during a transformation of a phase-change material, the pressurized energy storage module transmitting hydraulic oil to the phase-change heat exchange module; transmitting the hydraulic oil inside the oil bag module to the pressurized energy storage module to descend the lifting device; controlling the drive energy storage module to transmit hydraulic oil to the oil bag module for rising the lifting device; and during a transformation of the phase-change material, transmitting the hydraulic oil in the phase-change heat exchange module to the drive energy storage module.

Abstract: A driving method is implemented to a lifting device of an underwater survey system, and the lifting device includes a phase-change heat exchange module, an oil bag module, a pressurized energy storage module, and a drive energy storage module. The driving method includes: controlling the pressurized energy storage module to extract hydraulic oil in the oil bag module to descend the lifting device; during a transformation of a phase-change material, the pressurized energy storage module transmitting hydraulic oil to the phase-change heat exchange module; transmitting the hydraulic oil inside the oil bag module to the pressurized energy storage module to descend the lifting device; controlling the drive energy storage module to transmit hydraulic oil to the oil bag module for rising the lifting device; and during a transformation of the phase-change material, transmitting the hydraulic oil in the phase-change heat exchange module to the drive energy storage module.

Abstract: The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

Abstract: The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

Abstract: This disclosure describes methods, non-transitory computer readable storage media, and systems that provide secure password sharing across a plurality of users and client devices via a shared folder. For example, in one or more embodiments, the disclosed system retrieves a public key set including public encryption keys for client devices having access to the shared folder. The disclosed system provides the public key set to a client device requesting to share the shared folder. The disclosed system receives an encrypted payload for the shared folder and a shared encryption key that is utilized to encrypt the payload and is encrypted in the shared folder utilizing the public key set. The disclosed system also detects key rotation events and notifies one or more client devices to generate a modified shared encryption key and re-encrypt the payload for storage within the shared folder.

Abstract: The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

Abstract: The present disclosure provides compounds and compositions thereof which are useful as inhibitors of JAK2 and which exhibit desirable characteristics for the same.