Abstract: The present invention relates to novel small molecules Formula I and pharmaceutically acceptable salts thereof as well as the preparation and the use thereof to inhibit FGF13-1b.

Abstract: Provided by the present disclosure are a 4D (four-dimensional) intracardiac echocardiography (ICE) imaging system, an ultrasonic imaging method and an ultrasonic imaging apparatus. The system at least includes an interventional catheter, an external mechanical driving apparatus, and an ultrasonic host. The interventional catheter includes a miniature ultrasonic probe located at a distal end. The ultrasonic host is connected to the miniature ultrasonic probe, and used to output an acoustic wave driving signal. The miniature ultrasonic probe is used to emit the acoustic wave driving signal intermittently. The mechanical driving apparatus is used to drive the probe to rotate unidirectionally and uniformly in the interventional catheter when the probe emits the acoustic wave driving signal, thus performing mechanical 4D scanning imaging. The miniature ultrasonic probe is also used to receive an echo signal of the acoustic wave driving signal, and to transmit the echo signal to the ultrasonic host.

Abstract: Provided is a fan grow light. The fan grow light is configured to be mounted in a tent. The fan grow light includes a lamp board assembly and a fan assembly disposed on the lamp board assembly. The fan assembly is able to promote air circulation in the tent. The fan grow light can promote air circulation in the tent, enable plants to breathe better, inhibit molds, and promote plant growth.

Abstract: A device and method for regulating the release of adenosine in an organism, and the use thereof. The device comprises a stimulus generator for generating stimuli of a specific frequency. The use of the device of the present invention in an organism can effectively increase the concentration of adenosine in the brain of the organism, thereby providing an effective strategy for the improvement of sleep disorders.

Abstract: A first device sends first information to a second device, where the first information includes at least one of an identifier of the first device, position information of the first device, configuration information of the first device, or a time point at which the first device obtains second information, where the second information includes artificial intelligence information and/or sensing information. The second device determines indication information based on the first information and sends the indication information to the first device, where the indication information indicates a type and/or a format of information to be transmitted by the first device. The first device determines third information based on the indication information, where the third information is the second information or a part of the second information, or is determined based on the second information. The first device sends the third information to the second device.

Abstract: An oxygen evolution reduction electrocatalyst includes a pyrochlore compound with the chemical formula Sm2Ru2xM2-2xO7, where M is selected from the group consisting of Ir, Sc, Fe, Cu, Pd, Cr, and Rh, and x is less than 1.0 and greater than or equal to 0.5. Also, a water electrolysis cell includes an anode, a cathode, an electrolyte, and the oxygen evolution reduction electrocatalyst.

Abstract: The present invention relates to an antibody-drug conjugate (ADC) targeting Claudin18.2 and a composition containing the molecule. The present invention further relates to therapeutic and diagnostic uses of the antibodies and antibody fragments.

Abstract: In a memory error processing method, a processor of a computer apparatus obtains from a basic input/output system (BIOS) first error description information that describes a type of a first error that has occurred in a first memory page. Based on the first error description information, the processing device identifies the type of the first error to be a first type, wherein an error of the first type is a corrected error and is not a mirror scrub success error. The processor then determines that a number of errors of the first type that occurred in the first memory page has reached a threshold. In response to the determining, the processing device takes the first memory page offline.

Abstract: A battery cell, a battery, and an electric apparatus are described. A sampling module is connected to a housing and electrically connected to a conductor. At least one conductor is disposed on the housing and electrically connected to an electrode terminal. When status signals from the battery cell are collected, signals from at least one collection point of the sampling module are directly transmitted by the electrode terminal. In this way, the sampling module is integrated on the end cover and at least one conductor is electrically connected to the electrode terminal, which changes the conventional method of transmitting signals to CMC through a flexible circuit board and wiring harness, avoids the transmission of status signals from being affected by factors such as interference coupling and wiring harness short-circuiting, shortens the signal transmission path, and improves the reliability of signal collection by the sampling module.

Abstract: Provide is a wearable device comprising at least two electrodes and a wearable structure. The at least two electrodes are configured to fit against the skin of a human body to collect an electrocardiogram (ECG) signal of the human body, and the wearable structure is configured to carry the at least two electrodes and fit the at least two electrodes to a waist region of the human body. The at least two electrodes are spaced apart on the wearable structure, and disposed on two sides of a mid-sagittal plane of the human body when the human body wears the wearable structure.

Abstract: The present application relates to a silicone oil-based immersion coolant for an electronic component. The silicone oil-based immersion coolant for an electronic component includes a base oil and an additive. The base oil includes a low-viscosity silicone oil. The additive includes a silicone oil diluent and a thermally conductive inorganic filler. The viscosity of the low-viscosity silicone oil is less than or equal to 1000 cSt. The thermally conductive inorganic filler is an insulating filler. Based on the mass of the immersion coolant, a mass percentage content of the base oil is in a range from 70% to 85%, a mass percentage content of the silicone oil diluent is in a range from 10% to 20%, and a mass percentage content of the thermally conductive inorganic filler is in a range from 5% to 10%.

Abstract: The present disclosure provides a wearable device. The wearable device comprises at least two electrodes, configured to be attached to a human skin to collect an electrocardiograph (ECG) signal of a human body; a wearable structure, configured to carry the at least two electrodes and attach the at least two electrodes to two sides of a midsagittal plane of the human body; and a processor, configured to determine a heart rate variability (HRV) of the human body based on the ECG signal, and determine a physical state of the human body based at least on the HRV.

Abstract: A magnetic attraction assembly for the plant monitoring device is configured to detachably mount a plant monitoring device on an outer side of a tent and includes: a first connection member and a second connection member. The first connection member is arranged on an inner side surface of the tent or is integrated inside the tent. The second connection member is arranged on an outer side surface of the tent. One side surface of the second connection member is fixed to the plant monitoring device, at least one of the first connection member and the second connection member is a magnetic member, and the other side surface of the second connection member is attracted to the first connection member.

Abstract: Provided are a high-intensity focused ultrasound apparatus (10) and a control method. According to the high-intensity focused ultrasound apparatus (10), by providing a focusing transducer (120) having a freely transformable shape, after an entire transducer assembly (100) extends into an inner cavity of an object to be treated, the transducer assembly (100) can extend through a narrow part into the inner cavity of an object to be treated, and after extending into the inner cavity of the object to be treated, the shape of the focusing transducer (120) in the transducer assembly (100) changes, so that the effective area of the focusing transducer (120) increases, and the ultrasonic energy produced increases, thereby enhancing the irradiation intensity for a region to be treated, and satisfying normal operation requirements of the transducer assembly (100).

Abstract: Disclosed are an aromatic heterocyclic compound and an application thereof. The aromatic heterocyclic compound is represented by formula I, and the compound has good LSD1 enzyme inhibitory activity, and can be used as an LSD1 inhibitor for treatment of tumors etc.

Abstract: An electrocatalyst for the production of hydrogen from water includes a pyrochlore compound with a composition or chemical formula of RE2(Ru)2xM2-2xO7, RE2(Ir)2xM2-2xO7or RE2(Ir,Ru)2xM2-2xO7, where RE is a rare earth element, M is an alkali metal, alkaline carth metal, transition metal, post-transition metal, Ge, or Sb, and x is less than 1.0 and greater than 0.0.

Abstract: The embodiments of the present disclosure disclose a signal measurement circuit and method. The signal measurement circuit include: a plurality of electrodes configured to be attached to a human body and collect physiological signals of the human body; a contact impedance detection circuit electrically connected with the plurality of electrodes, the contact impedance detection circuit being configured to measure a contact impedance between each of the plurality of electrodes and the human body; and a switching circuit configured to control a conduction state between the plurality of electrodes and the contact impedance detection circuit, such that only a portion of the plurality of electrodes are in the conduction state with the contact impedance detection circuit simultaneously.

Abstract: Embodiments of the present disclosure provide a signal acquisition system including a wearable body; a plurality of electrodes fixed on the wearable body and in contact with the skin of a user, and a processing circuit. The plurality of electrodes include a first electrode set and a second electrode set, and the first electrode set is configured to acquire a physiological signal and the second electrode set is configured to acquire a detection signal. The processing circuit configured to eliminate, based on the detection signal, motion artifacts in the physiological signal.

Abstract: A preparation method of a Lentinula edodes polysaccharide rich in ?-glucan includes: (1) extracting the Lentinula edodes polysaccharide to obtain a filtrate; (2) concentrating the filtrate to obtain a supernatant; (3) precipitating a crude Lentinula edodes polysaccharide from the supernatant using anhydrous ethanol to obtain a first precipitate; and (4) purifying the first precipitate to obtain the Lentinula edodes polysaccharide. The Lentinula edodes polysaccharide rich in the ?-glucan has stable quality, and its yield, polysaccharide content and ?-glucan content are significantly improved compared with water extraction and alcohol precipitation methods in the related art. In vitro pharmacological experiments prove that the Lentinula edodes polysaccharide rich in the ?-glucan has good anti-inflammatory activity and can be applied to preparation of drugs or health foods.

Abstract: The present application provides, in some aspects, methods of treating cancers, such as homologous recombination (HR)-deficient cancers. In some embodiments, the disclosure provides a method for treating cancer by administering to a subject a compound of Formula (I):(I), or a pharmaceutically acceptable salt thereof.