Abstract: This disclosure relates to conditional double stranded antisense oligonucleotides and uses in managing diseases and conditions. In certain embodiments, the conditional double stranded antisense oligonucleotides are non-naturally occurring double stranded nucleobase polymer complexes comprising a first strand and a second strand, wherein the first strand is an antisense oligonucleotide connected to a segment that is partially identical to cell specific RNA, e.g., microRNA, and the second strand is a locking strand configured to release the first strand when in the presence of the cells specific RNA; thus, releasing the antisense oligonucleotide in a manner limited to cells that express a specific RNA.

Abstract: The present application relates to a method for preparing a pegylated collagen-like protein and the use thereof. The method includes reacting a collagen-like protein and a polyethylene glycol derivative at a molar ratio of the collagen-like protein to the polyethylene glycol derivative of 1 to 16:1 under the conditions of a pH of 6.0-8.0 and a temperature of 2-8° C. to prepare a pegylated collagen-like protein. In some embodiments, the reacting includes a reaction solvent of the collagen-like protein, and the polyethylene glycol derivative is water or a dilute hydrochloric acid solution. In some instances, the method may additionally include a purification step. The purification step may intercept substances with a molecular weight greater than or equal to 30,000 Da in the reaction product by filtration to obtain the PEGylated collagen-like protein.

Abstract: The present disclosure provides a superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery, and a preparation method thereof, belonging to the technical field of engineered nanovesicle drug loading systems. The superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery prepared by the preparation method acts on tumor cell lines. It is found that the superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery can specifically target tumor cells, induce tumor cell apoptosis, and inhibit tumor growth. The biological preparation significantly extends a survival time of mice and improves an efficacy of drugs against cancers.

Abstract: This provides a spatial multiplexing method and apparatus, to introduce WLAN sensing into a conventional spatial multiplexing mechanism and improve communication efficiency. The method includes: An AP sends a first request message to a first station and a second station, to request to measure channel quality in one or more sensing beam directions in a first SP; the AP sends a second request message to a third station and a fourth station, to request to measure channel quality in a communications beam direction in a second SP; the first station, the second station, the third station, and the fourth station separately perform measurement and report respective first measurement results; and the AP receives the first measurement results of the stations, and determines, based on the first measurement results, whether to perform spatial multiplexing on the first SP and the second SP.

Abstract: A temperature control system (300) for a variable frequency drive (10, 100) includes a sealed enclosure (310), a power electronic component (330) and/or a power magnetic component (320) positioned inside the sealed enclosure (310), and a controller (400) configured to control a temperature of the power electronic component (330) and/or the power magnetic component (320) relative to an internal air temperature (Tair) inside the sealed enclosure (310) prior to an electrical energy application and operation of the power electronic component (320) and/or power magnetic component (320) to prevent condensation induced electrical failure of the power electronic component (330) and/or power magnetic component (320) utilizing a cooling system (340) and/or a heating system (350).

Abstract: A method for assisting in locating a target object, a method for locating a target object, and an apparatus. In an embodiment, the method for assisting in locating a target object is applied to a station (STA), and the method includes: receiving a wireless sensing sounding frame including radar measurement indication information from an access point (AP); sending an uplink data packet to the AP, recording a first sending moment, and performing radar measurement on a target object based on the radar measurement indication information to obtain a radar measurement result; receiving a downlink data packet from the AP, and recording a first receiving moment; and sending the first sending moment, the first receiving moment and the radar measurement result to the AP.

Abstract: Embodiments are generally directed to sparse 3D convolution acceleration in a convolutional layer of an artificial neural network model. An embodiment of an apparatus includes one or more processors including a graphics processor to process data; and a memory for storage of data, including feature maps. The one or more processors are to provide for sparse 3D convolution acceleration by applying a shared 3D convolutional kernel/filter to an input feature map to produce an output feature map, including increasing sparsity of the input feature map by partitioning it into multiple disjoint input groups; generation of multiple disjoint output groups corresponding to the input groups by performing a convolution calculation represented by the shared 3D convolutional kernel/filter on all feature values associated with active/valid voxels of each input group to produce corresponding feature values within corresponding output groups; and outputting the output feature map by sequentially stacking the output groups.

Abstract: A temperature control system (300) for a variable frequency drive (10, 100) includes a sealed enclosure (310), a power electronic component (330) and/or a power magnetic component (320) positioned inside the sealed enclosure (310), and a controller (400) configured to control a temperature of the power electronic component (330) and/or the power magnetic component (320) relative to an internal air temperature (Tair) inside the sealed enclosure (310) prior to an electrical energy application and operation of the power electronic component (320) and/or power magnetic component (320) to prevent condensation induced electrical failure of the power electronic component (330) and/or power magnetic component (320) utilizing a cooling system (340) and/or a heating system (350).