Patents by Inventor Jiajin FENG

Jiajin FENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9018373
    Abstract: A method for preparing temsirolimus, the method including: using a substituted aromatic aldehyde to protect 2,2-dimethylol propionic acid to produce intermediate II; carrying out reaction between the intermediate II and 2,4,6-trichlorobenzoyl chloride; carrying out condensation reaction between a resulting product and rapamycin to produce intermediate III; and finally using sulfuric acid to remove a protecting group from the intermediate III to yield temsirolimus.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: April 28, 2015
    Assignee: Tianjin Weijie Technology Co., Ltd.
    Inventors: Honghai Song, Long Tang, Wei Chen, Zheng Li, Jinzhou Li, Zhicun Sun, Jiajin Feng
  • Patent number: 8822678
    Abstract: A method for synthesizing temsirolimus, the method including: using a substituted boric acid to protect 2,2-dimethylol propionic acid to produce intermediate II; carrying out a reaction between the intermediate II and 2,4,6-trichlorobenzoyl chloride; carrying out condensation reaction between a resulting product and rapamycin to produce intermediate III; and finally using a diol to remove a protecting group from the intermediate III to yield temsirolimus.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: September 2, 2014
    Assignee: Tianjin Wiejie Technology Co., Ltd.
    Inventors: Honghai Song, Long Tang, Wei Chen, Zheng Li, Jinzhou Li, Zhicun Sun, Jiajin Feng
  • Publication number: 20130296572
    Abstract: A method for preparing temsirolimus, the method including: using a substituted aromatic aldehyde to protect 2,2-dimethylol propionic acid to produce intermediate II; carrying out reaction between the intermediate II and 2,4,6-trichlorobenzoyl chloride; carrying out condensation reaction between a resulting product and rapamycin to produce intermediate III; and finally using sulfuric acid to remove a protecting group from the intermediate III to yield temsirolimus.
    Type: Application
    Filed: July 3, 2013
    Publication date: November 7, 2013
    Inventors: Honghai SONG, Long TANG, Wei CHEN, Zheng LI, Jinzhou LI, Zhicun SUN, Jiajin FENG
  • Publication number: 20130296550
    Abstract: A method for synthesizing temsirolimus, the method including: using a substituted boric acid to protect 2,2-dimethylol propionic acid to produce intermediate II; carrying out a reaction between the intermediate II and 2,4,6-trichlorobenzoyl chloride; carrying out condensation reaction between a resulting product and rapamycin to produce intermediate III; and finally using a diol to remove a protecting group from the intermediate III to yield temsirolimus.
    Type: Application
    Filed: July 1, 2013
    Publication date: November 7, 2013
    Inventors: Honghai SONG, Long TANG, Wei CHEN, Zheng LI, Jinzhou LI, Zhicun SUN, Jiajin FENG