Patents by Inventor Jiali Du

Jiali Du has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210054079
    Abstract: This disclosure relates to formulations and compositions of an antibody directed against human anti-PD-L1, such as durvalumab.
    Type: Application
    Filed: April 24, 2019
    Publication date: February 25, 2021
    Inventors: James Biddlecombe, Jenny Main, Jiali Du, Methal Albarghouthi
  • Publication number: 20190382494
    Abstract: Provided herein are compositions comprising coformulation of anti-PD-L1 and anti-CTLA-4 antibodies, or antigen-binding fragments thereof, and methods of making and using such compositions. In various aspects, stable coformulations of the anti-PD-L1 antibody durvalumab (MEDI4736) and the anti-CTLA-4 antibody tremelimumab are provided.
    Type: Application
    Filed: August 28, 2019
    Publication date: December 19, 2019
    Inventors: JIALI DU, AMBARISH SHAH
  • Patent number: 10421811
    Abstract: Provided herein are compositions comprising coformulation of anti-PD-L1 and anti-CTLA-4 antibodies, or antigen-binding fragments thereof, and methods of making and using such compositions. In various aspects, stable coformulations of the anti-PD-L1 antibody durvalumab (MEDI4736) and the anti-CTLA-4 antibody tremelimumab are provided.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: September 24, 2019
    Assignee: MEDIMMUNE, LLC
    Inventors: Jiali Du, Ambarish Shah
  • Publication number: 20170306025
    Abstract: Provided herein are compositions comprising coformulation of anti-PD-L1 and anti-CTLA-4 antibodies, or antigen-binding fragments thereof, and methods of making and using such compositions. In various aspects, stable coformulations of the anti-PD-L1 antibody durvalumab (MEDI4736) and the anti-CTLA-4 antibody tremelimumab are provided.
    Type: Application
    Filed: April 24, 2017
    Publication date: October 26, 2017
    Inventors: Jiali DU, Ambarish Shah
  • Publication number: 20150239970
    Abstract: The present invention relates to a stable, low viscosity antibody formulation, wherein the formulation comprises a high concentration of anti-IL6 antibody. In some embodiments, the invention is directed to a stable, low viscosity antibody formulation comprising about 50 mg/mL to about 400 mg/mL of an anti-IL6 antibody, and arginine, wherein the antibody formulation is in an aqueous solution and has a viscosity of less than 20 cP at 23° C. Also provided are methods of making and methods of using such antibody formulations.
    Type: Application
    Filed: October 23, 2013
    Publication date: August 27, 2015
    Inventors: Jared Bee, Paul Santacroce, Jiali Du, Mariana Dimitrova