Abstract: Disclosed is a microreactor for continuous flow synthesis of 2,5-furandicarboxylic acid, the microreactor includes a first container, a collection device, an injection pump, a first flow pump, a second flow pump, a first microreactor substrate, ion exchange resin adsorption pipes, activated carbon adsorption pipes, a second microreactor substrate, an oxygen source, a first T-connector, a second T-connector, and a third T-connector; where the first container is connected to the first T-connector via the first flow pump, the injection pump is connected to the first T-connector, the third T-connector is connected to the first T-connector and the first microreactor substrate, respectively, the first microreactor substrate is connected to the ion exchange resin adsorption pipes, the activated carbon adsorption pipes, the second T-connector, and the second microreactor substrate in sequence, and the oxygen source is connected to the second T-connector.