Patents by Inventor Jiamin Gu

Jiamin Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline form of 3-((L-valyl)amino))-3,3-dideuterium-1-propanesulfonic acid, preparation method and uses thereof
    Patent number: 11186543
    Abstract: The present invention relates to a crystalline form of compound 3-((L-valyl)amino)-3,3-dideuterium-1-propanesulfonic acid, preparation method and uses thereof.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: November 30, 2021
    Assignee: RISEN (SUZHOU) PHARMA TECH CO., LTD.
    Inventors: Jiasheng Lu, Jiamin Gu, Daiqiang Hu, Xianqi Kong
  • ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF
    Publication number: 20210347731
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Application
    Filed: January 4, 2021
    Publication date: November 11, 2021
    Inventors: Jiasheng LU, Jiamin GU, Xinyong LV, Guowei SONG, Dongdong WU, Daiqiang HU, Jun GU, Gang CHEN, Xiang JI, Xiuchun ZHANG, Jinchao AI, Xianqi KONG
  • CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF
    Publication number: 20210139526
    Abstract: CD73 (also known as ecto-5?-nucleotidase) inhibitor compounds are provided, as well as compositions and uses thereof for treating or preventing CD73-associated or related diseases, disorders and conditions, including cancer- and immune-related disorders. CD73 inhibitor compounds include compounds having the structure set forth in Formula I and pharmaceutically acceptable esters or salts thereof.
    Type: Application
    Filed: December 23, 2020
    Publication date: May 13, 2021
    Inventors: Jiasheng LU, Jiamin GU, Gang CHEN, Feng ZHOU, Qiguo ZHANG, Xuli WANG, Xiang JI, Lin WANG, Xianqi KONG
  • Isotope-enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof
    Patent number: 10954188
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: March 23, 2021
    Assignee: RISEN (SUZHOU) PHARMA TECH CO., LTD.
    Inventors: Jiasheng Lu, Jiamin Gu, Xinyong Lv, Guowei Song, Dongdong Wu, Daiqiang Hu, Jun Gu, Gang Chen, Xiang Ji, Xiuchun Zhang, Jinchao Ai, Xianqi Kong
  • PRODRUGS OF THE TYROSINE KINASE INHIBITOR FOR TREATING CANCER
    Publication number: 20210078970
    Abstract: There are provided compounds of Formula I, and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, useful for inhibition or modulation of the activity of tyrosine kinases and treatment of disease states or conditions mediated by tyrosine kinases, including cancers.
    Type: Application
    Filed: August 28, 2020
    Publication date: March 18, 2021
    Inventors: Jiasheng LU, Jiamin GU, Gang CHEN, Qiguo ZHANG, Chengyong SUN, Xianqi KONG
  • GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS
    Publication number: 20210079033
    Abstract: There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.
    Type: Application
    Filed: December 17, 2018
    Publication date: March 18, 2021
    Inventors: Xianqi KONG, Jiasheng LU, Jiamin GU, Xiang JI, Daiqiang HU, Xiuchun ZHANG, Xinyong LV, Jinchao AI, Dongdong WU, Lin WANG, Dongqing ZHU, Xiaolin HE
  • CRYSTALLINE FORM OF 3- ((L-VALYL) AMINO)) -3, 3-DIDEUTERIUM-1-PROPANESULFONIC ACID, PREPARATION METHOD AND USES THEREOF
    Publication number: 20210053914
    Abstract: The present invention relates to a crystalline form of compound 3-((L-valyl)amino)-3,3-dideuterium-1-propanesulfonic acid, preparation method and uses thereof.
    Type: Application
    Filed: December 28, 2018
    Publication date: February 25, 2021
    Inventors: Jiasheng LU, Jiamin GU, Daiqiang HU, Xianqi KONG
  • CD73 inhibitors and pharmaceutical uses thereof
    Patent number: 10881681
    Abstract: CD73 (also known as ecto-5?-nucleotidase) inhibitor compounds are provided, as well as compositions and uses thereof for treating or preventing CD73-associated or related diseases, disorders and conditions, including cancer- and immune-related disorders. CD73 inhibitor compounds include compounds having the structure set forth in Formula I and pharmaceutically acceptable esters or salts thereof.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: January 5, 2021
    Assignee: RISEN (SUZHOU) PHARMA TECH CO., LTD.
    Inventors: Jiasheng Lu, Jiamin Gu, Dongdong Wu, Gang Chen, Chengyong Sun, Xiang Ji, Lin Wang, Feng Zhou, Xiuchun Zhang, Xianqi Kong
  • PRODRUGS OF A CDK INHIBITOR FOR TREATING CANCERS
    Publication number: 20200339615
    Abstract: There are provided compounds of Formula I, and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for inhibition or modulation of the activity of cyclin dependent kinases (CDK) and/or glycogen synthase kinase-3 (GSK-3), for the treatment of disease states or conditions mediated by cyclin dependent kinases and/or glycogen synthase kinase-3, including cancers.
    Type: Application
    Filed: April 23, 2020
    Publication date: October 29, 2020
    Inventors: Jiasheng LU, Jiamin GU, Gang CHEN, Xiaolin ZHANG, Feng ZHOU, Xianqi KONG
  • ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF
    Publication number: 20200223793
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Application
    Filed: October 17, 2019
    Publication date: July 16, 2020
    Inventors: Jiasheng LU, Jiamin GU, Xinyong LV, Guowei SONG, Dongdong WU, Daiqiang HU, Jun GU, Gang CHEN, Xiang JI, Xiuchun ZHANG, Jinchao AI, Xianqi KONG
  • CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF
    Publication number: 20200078388
    Abstract: CD73 (also known as ecto-5?-nucleotidase) inhibitor compounds are provided, as well as compositions and uses thereof for treating or preventing CD73-associated or related diseases, disorders and conditions, including cancer- and immune-related disorders. CD73 inhibitor compounds include compounds having the structure set forth in Formula I and pharmaceutically acceptable esters or salts thereof.
    Type: Application
    Filed: September 10, 2019
    Publication date: March 12, 2020
    Inventors: Jiasheng LU, Jiamin GU, Dongdong WU, Gang CHEN, Chengyong SUN, Xiang JI, Lin WANG, Feng ZHOU, Xiuchun ZHANG, Xianqi KONG
  • Isotope-enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof
    Patent number: 10472323
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: November 12, 2019
    Assignee: RISEN (SUZHOU) PHARMA TECH CO., LTD.
    Inventors: Jiasheng Lu, Jiamin Gu, Xinyong Lv, Guowei Song, Dongdong Wu, Daiqiang Hu, Jun Gu, Gang Chen, Xiang Ji, Xiuchun Zhang, Jinchao Ai, Xianqi Kong
  • GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF
    Publication number: 20190185502
    Abstract: There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.
    Type: Application
    Filed: December 17, 2018
    Publication date: June 20, 2019
    Inventors: Jiasheng LU, Jiamin GU, Xiang JI, Daiqiang HU, Xiuchun ZHANG, Xinyong LV, Jinchao AI, Dongdong WU, Xianqi KONG, Lin WANG, Dongqing ZHU, Xiaolin HE
  • ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF
    Publication number: 20180273471
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Application
    Filed: March 31, 2017
    Publication date: September 27, 2018
    Inventors: Jiasheng Lu, Jiamin Gu, Xinyong Lv, Guowei Song, Dongdong Wu, Daiqiang Hu, Jun Gu, Gang Chen, Xiang Ji, Xiuchun Zhang, Jinchao Ai, Xianqi Kong
  • COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM
    Publication number: 20130287700
    Abstract: Subject of the present invention are compounds with high affinity for the A? protein, ?-synuclein or for Tau-PHF aggregates, which are suitable as preferably fluorescent probes for the in vivo diagnosis of neurodegenerative disorders like e.g. Alzheimer's disease and Parkinson's disease. The compounds are characterized by suitable physicochemical properties (excitation wavelength, emission wavelength, Stokes shift, extinction) as well as a high affinity and selectivity for the target proteins.
    Type: Application
    Filed: September 20, 2011
    Publication date: October 31, 2013
    Applicants: KLINIKUM DARMSTADT GMBH, TECHNISCHE UNIVERSITAT DARMSTADT, LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN
    Inventors: Boris Schmidt, Daniel Kieser, Alexander Boländer, Jochen Herms, Roland Heyny-Von Haussen, Jiamin Gu