Abstract: The disclosure relates to a method and system for processing information in a content delivery network (CDN). The method includes: obtaining total bandwidth values at respective sampling time points within a management cycle, and arranging the total bandwidth values in chronological order; determining an interval between a first sampling time point and a second sampling time point as a management interval; determining usage ratios of respective bandwidth users according to a first bandwidth value used within the management interval by the bandwidth users sharing the CDN bandwidth, and a second bandwidth value in total used within the management interval by all of the bandwidth users sharing the CDN bandwidth; and managing, based on the usage ratios, bandwidth usage by the respective bandwidth users.

Abstract: Disclosed are a series of compounds with a nitrogen-containing spiro structure and an application thereof in the preparation of an RET kinase inhibitor. Specifically, disclosed is a compound as shown in formula (II) or a pharmaceutically acceptable salt thereof.

Abstract: A data modulation method, a communication device and a storage medium are disclosed. The data modulation method includes: performing a preset modulation operation on B consecutive data blocks, and configuring the B consecutive data blocks to have a same head-end reference signal sequence and/or a same tail-end reference signal sequence; inserting Z zeros between adjacent time domain data of the B consecutive data blocks; performing a filtering operation on the B consecutive data blocks into which Z zeros have been inserted, and transmitting the filtered data on a physical resource, where B is greater than or equal to 2 (i.e., B?2), and Z is greater than or equal to 0 (i.e., Z?0).

Abstract: The present invention discloses a right-angle turning method for small-diameter TBM exploration adit excavation and belongs to the field of geological exploration of water conservancy and hydropower projects.

Abstract: The present invention generally relates to topical compositions and methods of using the same. A preferred topical pharmaceutical composition comprises a nitric oxide-releasing active pharmaceutical ingredient in admixture with a hydrophilic composition and a hydrophobic composition wherein the nitric oxide-releasing active pharmaceutical ingredient comprises a nitric oxide-releasing compound having a diazeniumdiolate functional group.

Abstract: The invention discloses a design method of a wavenumber linearity dispersion optical system and an imaging spectrometer, including: building an optical system including a grating, a prism and an objective lens that are sequentially arranged, the grating adjoins the prism; defining a linearity evaluation coefficient RMS; assigning a minimum value to the linearity evaluation coefficient RMS through adjustment to the vertex angle of the prism, when the linearity evaluation coefficient RMS is at minimum, the vertex angle of the prism being ?1; acquiring compensations for distortion and longitudinal chromatic aberration of the objective lens based on the interval between equal-difference wavenumbers on the image plane when the vertex angle of the prism is ?1; and optimizing the objective lens based on the compensations for distortion and longitudinal chromatic aberration of the objective lens to obtain an optimized optical system.

Abstract: Provided are a target character video clip playing method, system and apparatus, and a storage medium. The method comprises: using image recognition technology to perform target character recognition on an entire video, positioning a plurality of video clips containing target characters, and obtaining a first playing time period set corresponding to the video clips; according to audio clips corresponding to each character marked within the entire video, obtaining a second playing time period set corresponding to the audio clips of the various characters; merging the time periods included in the playing time period sets, and obtaining a sum playing time period set of the target characters; according to a sorting of various playing timelines within the sum playing time period set, performing video playing of the target characters.

Abstract: Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein.

Abstract: Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein.

Abstract: Provided are a target character video clip playing method, system and apparatus, and a storage medium. The method comprises: using image recognition technology to perform target character recognition on an entire video, positioning a plurality of video clips containing target characters, and obtaining a first playing time period set corresponding to the video clips; according to audio clips corresponding to each character marked within the entire video, obtaining a second playing time period set corresponding to the audio clips of the various characters; merging the time periods included in the playing time period sets, and obtaining a sum playing time period set of the target characters; according to a sorting of various playing timelines within the sum playing time period set, performing video playing of the target characters.

Abstract: The present disclosure discloses a method of interaction between a television and a mobile terminal, including: the server acquiring a current program image and a positioning mark of a smart television; the server identifying the current program image to determine program information, the program being currently played by the smart television; the server sending the program information to a mobile terminal whose positioning mark matches the positioning mark of the smart television; the mobile terminal acquiring live broadcast or live broadcast comment related to the program currently played by the smart television from a mobile live broadcast platform based on the received program information. The present disclosure also provides a system of interaction between a television and a mobile terminal.

Abstract: The present disclosure provides formulations for pharmacologically active reagents, including formulations based on particulates formed from a biodegradable polymer (e.g., a polysaccharide such as dextran) linked to a vitamin or related agent (e.g., folic acid). Hydrophobic pharmaceutically active agents (such as anti-cancer drugs, e.g., paclitaxel) are encapsulated into the polysaccharide-vitamin conjugate for the administration of paclitaxel. The active agent is in a core portion of the particulate, instead of on the surface of the particulate. Processes for making and using the particulates and compositions comprising the same are also disclosed. In particular, methods of cancer diagnosis and treatment are provided.

Abstract: Dual blade wide-format lawn mower, with an engine on the chassis, and a grass cutter disc that includes two parallel cutter shafts, each with a cutting blade on an lower end; each with a cutter shaft bevel gear on the top end, each engaged with a transmission bevel gear on an outer end of a horizontal shaft; both horizontal shafts are co-axial, each shaft and same side cutter shaft supported by a bearing in a cutter shaft seat; fixed onto the chassis, and opposing ends of both shafts extend from the respective cutter shaft seat and mounted with a drum-type gear, both engaged respectively with spline internal teeth at both ends of an internally toothed sleeve; one cutter shaft upper end extends the cutter shaft seat and is mounted with a cutter shaft pulley transmission connected with an engine pulley via driving belt.

Abstract: The present invention generally relates to topical compositions and methods of using the same. The topical compositions may comprise a hydrophilic composition and a hydrophobic composition in admixture. The hydrophobic composition may include a nitric oxide-releasing compound such as, for example, a diazeniumdiolate functionalized co-condensed silica particle. In some embodiments, the topical composition may be self-emulsifying. Further described herein are kits comprising a hydrophilic composition and a hydrophobic composition.

Abstract: The present disclosure provides formulations for pharmacologically active reagents, including formulations based on particulates formed from a biodegradable polymer (e.g., a polysaccharide such as dextran) linked to a vitamin or related agent (e.g., folic acid). Hydrophobic pharmaceutically active agents (such as anti-cancer drugs, e.g., paclitaxel) are encapsulated into the polysaccharide-vitamin conjugate for the administration of paclitaxel. The active agent is in a core portion of the particulate, instead of on the surface of the particulate. Processes for making and using the particulates and compositions comprising the same are also disclosed. In particular, methods of cancer diagnosis and treatment are provided.

Abstract: Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein.

Abstract: The present application discloses a pharmaceutical composition for in vivo delivery. The pharmaceutical composition includes a pharmacologically active agent and a pharmaceutically acceptable carrier. The pharmaceutically acceptable carrier includes a biocompatible polymer. The biocompatible polymer and the pharmacologically active agent are formulated as particles. The pharmaceutical composition is free of a water-immiscible solvent.

Abstract: The present disclosure provides formulations for pharmacologically active reagents, including formulations based on particulates formed from a biodegradable polymer (e.g., a polysaccharide such as dextran) linked to a vitamin or related agent (e.g., folic acid). Hydrophobic pharmaceutically active agents (such as anti-cancer drugs, e.g., paclitaxel) are encapsulated into the polysaccharide-vitamin conjugate for the administration of paclitaxel. The active agent is in a core portion of the particulate, instead of on the surface of the particulate. Processes for making and using the particulates and compositions comprising the same are also disclosed. In particular, methods of cancer diagnosis and treatment are provided.

Abstract: The present invention generally relates to topical compositions and methods of using the same. The topical compositions may comprise a hydrophilic composition and a hydrophobic composition in admixture. The hydrophobic composition may include a nitric oxide-releasing compound such as, for example, a diazeniumdiolate functionalized co-condensed silica particle. In some embodiments, the topical composition may be self-emulsifying. Further described herein are kits comprising a hydrophilic composition and a hydrophobic composition.

Abstract: Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein.