Patents by Inventor Jian Cheng Tu

Jian Cheng Tu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein encoded by a nucleic acid
    Patent number: 7378498
    Abstract: A method is provided for identifying a compound that modulates a cellualr response associated with Homer and mediated by a cell-surface or an intracellular receptor. A method is further provided for identifying a compound that modulates receptor activated calcium mobilization associated with Homer. A method is provided for identifying a compound that inhibits Homer protein activity based on the crystal structure coordinates of Homer protein binding domain. A method is also provided for identifying a compound that affects the formation of cell surface receptors into clusters. Also provided are nucleic acids encoding Homer proteins as well as Homer proteins, and Homer interacting proteins.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: May 27, 2008
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: Paul F. Worley, Jian Cheng Tu, Bo Xiao, Daniel Leahy, Jutta Beneken, Anthony A. Lanahan, Paul R. Brakeman
  • Nucleic acid molecule encoding homer 2a protein
    Patent number: 6864083
    Abstract: A method is provided for identifying a compound that modulates a cellualr response associate with Homer and mediated by a cell-surface or an intracellular receptor. A method is further provided for identifying a compound that modulates receptor activated calcium mobilization associated with Homer. A method is provided for identifying a compound that inhibits Homer protein activity based on the crystal structure coordinates of Homer protein binding domain. A method is also provided for identifying a compound that affects the formation of cell surface receptors into clusters. Also provided are nucleic acids encoding Homer proteins as well as Homer proteins, and Homer interacting proteins.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: March 8, 2005
    Inventors: Paul F. Worley, Jian Cheng Tu, Bo Xiao, Daniel Leahy, Jutta Beneken, Anthony A. Lanahan, Paul R. Brakeman
  • Nucleic acid molecule encoding homer 1B protein
    Patent number: 6720175
    Abstract: A method is provided for identifying a compound that modulates a cellular response associated with Homer and mediated by a cell-surface or an intracellular receptor. A method is further provided for identifying a compound that modulates receptor activated calcium mobilization associated with Homer. A method is provided for identifying a compound that inhibits Homer protein activity based on the crystal structure coordinates of Homer protein binding domain. A method is also provided for identifying a compound that affects the formation of cell surface receptors into clusters. Also provided are nucleic acids encoding Homer proteins as well as Homer proteins, and Homer interacting proteins.
    Type: Grant
    Filed: August 18, 1999
    Date of Patent: April 13, 2004
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: Paul F. Worley, Jian Cheng Tu, Bo Xiao, Daniel Leahy, Jutta Beneken, Anthony A. Lanahan, Paul R. Brakeman
  • Nucleic acid molecule encoding homer 1b protein
    Publication number: 20030170807
    Abstract: A method is provided for identifying a compound that modulates a cellualr response associate with Homer and mediated by a cell-surface or an intracellular receptor. A method is further provided for identifying a compound that modulates receptor activated calcium mobilization associated with Homer. A method is provided for identifying a compound that inhibits Homer protein activity based on the crystal structure coordinates of Homer protein binding domain. A method is also provided for identifying a compound that affects the formation of cell surface receptors into clusters. Also provided are nucleic acids encoding Homer proteins as well as Homer proteins, and Homer interacting proteins.
    Type: Application
    Filed: July 9, 2002
    Publication date: September 11, 2003
    Applicant: The Johns Hopkins University School of Medicine
    Inventors: Paul F. Worley, Jian Cheng Tu, Bo Xiao, Daniel Leahy, Jutta Beneken, Anthony A. Lanahan, Paul R. Brakeman