Abstract: A transgenic strain for producing 3-hydroxy-3-methylbutyric acid is provided. The transgenic strain comprises a host cell with an anabolic pathway for converting carbon sources into acetyl-CoA and a plurality of exogenous genes. These exogenous genes comprise genes encoding acetyl-CoA acetyltransferase (AtoB) or acetoacetyl-CoA thiolase (NphT7), and genes encoding hydroxymethylglutaryl-CoA synthetase (MvaS), a gene encoding 3-hydroxy-3-methylglutaconyl-CoA dehydratase (LiuC), a gene encoding 3-methylglutaryl-CoA decarboxylase (AibAB), a gene encoding thioester hydrolase (YciA, TesB, MenI or YqiA). A method for producing 3-hydroxy-3-methylbutyric acid using the above genetically modified strain is also provided.

Abstract: A dendritic cell (DC)-targeting M13 phage vaccine platform is provided herewith, where spy-tagged neoantigens can be attached to the phage surface with spy-catchers. By expressing DC-targeting peptides and spy-catchers as foreign antigens on the phage surface, its therapeutic and antigenic properties can be enhanced to combat solid cancers. SLS-spy catcher phage (SCP), with or without neoantigen conjugation, significantly repressed tumour growth by boosting systemic anti-tumour immunity and increasing intratumoral infiltration of both innate and adaptive immune cells. Intratumoral administration of SCP also hugely reduced PDL1 expression on tumour cells, making them more susceptible to immune attacks. Additionally, SCP administration restricted the size of blood vessels inside the tumour mass, suggesting multiple factors contribute to restrict tumour growth.

Abstract: A vision-based target tracking method, a system, an equipment, and a storage medium. The method includes: acquiring face positions and body positions in a current image frame; acquiring a current position of a time-series tracking target by a time-series tracking algorithm; determining, when a face matching the face of a to-be-tracked target does not exist outside a region corresponding to the current position of the time-series tracking target, whether the time-series tracking target is in an intersecting state; determining whether a body matching the body of the to-be-tracked target in other persons intersecting the times-series tracking target when in the intersecting state, or using the current position of the time-series tracking target as a current target position if not in the intersecting state; and taking the current target position as the position of the to-be-tracked target in the previous frame, and returning to the above steps.

Abstract: Embodiments relate to dynamic horizontal autoscaling for a multi-tenant service. According to an aspect, a computer-implemented method includes configuring a network computing element to route a plurality of requests from two or more clients to a service in a containerized-networked system. A horizontal service-level autoscaler monitors one or more aspects of the requests to the service from the two or more clients. A new pod including a set of running containers with shared resources in the containerized-networked system is created based at least in part on the horizontal service-level autoscaler determining that at least one of the one or more aspects of the requests exceeds a threshold. A new service mapping is created to accept subsequent requests from one of the two or more clients that triggered creation of the new pod.

Abstract: A system may include a memory and a processor in communication with the memory. The processor may be configured to perform operations. The operations may include calculating a priority factor with a node autonomous center in a node and computing a node service capability with the node autonomous center. The operations may further include selecting, with the node autonomous center, a task based on the priority factor and the node service capability. The operations may further include directing the task to the node.

Abstract: A flash memory method includes: classifying data into a plurality of groups of data; respectively executing error code encoding to generate first corresponding parity check code to store the groups of data and first corresponding parity check code into flash memory module as first blocks; reading out the groups of data from first blocks; executing error correction and de-randomize operation upon read out data to generate de-randomized data; executing randomize operation upon de-randomized data according to a set of seeds to generate randomized data; performing error code encoding upon randomized data to generate second corresponding parity check code; and, storing randomized data and second corresponding parity check code into flash memory module as second block; a cell of first block is used for storing data of first bit number which is different from second bit number corresponding to a cell of second block.

Abstract: Described herein are liquid, organosilicon compounds that including a substituent that is a cyano (—CN), cyanate (—OCN), isocyanate (—NCO), thiocyanate (—SCN) or isothiocyanate (—NCS). The organosilicon compounds are useful in electrolyte compositions and can be used in any electrochemical device where electrolytes are conventionally used.

Abstract: A bike trainer includes a base seat unit including an axle member, a swing member including a main body, a first wing portion, and a second wing portion, a shock absorber unit including a first elastic member, and a second elastic member, and an accessory structure connected to the axle member and adapted to provide resistance to an exercise of a user. When the accessory structure swings the axle member rotates and the swing member swings between a left-leaning position and a right-leaning position. When the swing member is in the left-leaning position, the first wing portion compresses the first elastic member to generate a biasing force acting on the swing member in the clockwise direction. When the swing member is in the right-leaning position, the second wing portion compresses the second elastic member to generate a biasing force acting on the swing member in the anti-clockwise direction.

Abstract: An aerospace wiring harness inspection system comprises a mobile personal computing device; a camera system connected to the mobile personal computing device, a machine learning model running in the mobile personal computing device; and a controller. The machine learning model is trained to detect anomalies in a set of images of a wiring harness in an aerospace vehicle. The controller configured to control the camera system to generate a set of images of the wiring harness; send the set of images of the wiring harness to the machine learning model; and receive a result from the machine learning model indicating whether an anomaly is present in the wiring harness.

Abstract: A flash memory method includes: classifying data into a plurality of groups of data; respectively executing error code encoding to generate first corresponding parity check code to store the groups of data and first corresponding parity check code into flash memory module as first blocks; reading out the groups of data from first blocks; executing error correction and de-randomize operation upon read out data to generate de-randomized data; executing randomize operation upon de-randomized data according to a set of seeds to generate randomized data; performing error code encoding upon randomized data to generate second corresponding parity check code; and, storing randomized data and second corresponding parity check code into flash memory module as second block; a cell of first block is used for storing data of first bit number which is different from second bit number corresponding to a cell of second block.

Abstract: Apparatus for controlling multi-rotor vehicle vibrations and related methods are disclosed herein. An example apparatus includes a vibration level detector to determine a vibration level of a frame of a vehicle based on data received from a sensor of the vehicle, the vehicle including a rotor. The apparatus includes a rotor operation analyzer to determine an operational parameter of the rotor based on the vibration level. The apparatus includes a communicator to transmit an instruction including the operational parameter to a controller of the rotor.

Abstract: A method for stripping an encapsulation layer of a steel pipe is provided, which relates to the technical field of encapsulation layer stripping. The method mainly includes the following steps 1 to 6: step 1, a left part of the encapsulation layer is pre-stripped; step 2, a right part of the encapsulation layer is pre-stripped; step 3, an upper part of the encapsulation layer is pre-stripped; step 4, the upper part of the encapsulation layer is secondarily stripped; step 5, the lower part of the encapsulation layer is stripped, and the right and left parts of the encapsulation layer are secondarily stripped; and step 6, the encapsulation layer is completely stripped and the central pipe body of the steel pipe is completely exposed.

Abstract: Systems and methods are provided for receiving, from an access point, attributes of an Internet of Things (IoT) device connected to the access point, determining a stored device, in a database of a server, sharing a subset of the attributes of the IoT device, and generating a code bundle based on the subset of the shared attributes between the stored device and the IoT device.

Abstract: A pneumatic stripping tool is provided. A top end of a main base is connected with an upper plate through screws; a middle part of a top end of the upper plate is connected with a handle through screws; one end of the upper plate is connected with a pneumatic-wrench fixing seat collar through screws; a pneumatic wrench is connected between the handle and the pneumatic-wrench fixing seat collar; the outer side of one end of the pneumatic wrench is connected with a power wrench sleeve; mounting holes are formed in portions of the main base which are corresponding to the power wrench sleeve; the inner side of one end of the power wrench sleeve is connected with a bottom wheel; and the bottom wheel extends into an inside of the mounting hole.

Abstract: In an approach to improve workload orchestration in a multi-cloud environment, embodiments orchestrate and manage a workload in a decentralized multi-cloud environment using one or more smart contracts. Additionally, embodiments measure, by a competency measurement component, competency of cloud services based on one or more predefined cloud benchmarks, a consensus network, and the one or more smart contracts, and generate an orchestration plan that is a best fit for the workload. Furthermore, embodiments validate and update, by the consensus network and the one or more smart contracts, the generated orchestration plan, and executing the generated orchestration plan.

Abstract: Highly efficient process for the preparation of 4-Fluoro-1H-pyrazole or salts thereof by reaction of pyrazole with an electrophilic fluorinating reagent is disclosed.

Abstract: Embodiments relate to dynamic horizontal autoscaling for a multi-tenant service. According to an aspect, a computer-implemented method includes configuring a network computing element to route a plurality of requests from two or more clients to a service in a containerized-networked system. A horizontal service-level autoscaler monitors one or more aspects of the requests to the service from the two or more clients. A new pod including a set of running containers with shared resources in the containerized-networked system is created based at least in part on the horizontal service-level autoscaler determining that at least one of the one or more aspects of the requests exceeds a threshold. A new service mapping is created to accept subsequent requests from one of the two or more clients that triggered creation of the new pod.

Abstract: Equipment for stripping package includes a supporting frame, a driving air motor, a pressing assembly and a feeding carrier plate, wherein the pressing assembly is mounted in an interior of the supporting frame, an output end of the driving air motor is in transmission connection with the pressing assembly, and a feeding end of the supporting frame is connected with the feeding carrier plate. The pressing assembly includes a first transmission shaft and a second transmission shaft, the first transmission shaft is sleeved with a lower peeling roller, pressing tooth on the lower peeling roller and pressing tooth on the second transmission shaft are arranged in a staggered mode, and tearing operation of external packaging layers of cables is achieved by up-and-down pressing.

Abstract: A processor may automatically generate one or more transcripts based on a media context. The processor may append at least one of the one or more transcripts to the media. The processor may modify the at least one of the one or more transcripts based on an adjustment to a weight factor.

Abstract: Examples described herein relate to configuration of access points including Internet-of-Things (IoT) radio. An access point identifier list is received from a network administration node in a network. Each access point identifier in the access point identifier list is uniquely associated with an access point, which includes an IoT radio. A first rules list is received from the network administration node. Each rule in the first rules list indicates a constraint and access point configuration values. An objective function is used to identify access point identifiers satisfying one or more of the constraints in the rules. The access points associated with the identified access point identifiers are configured with the access point configuration values as indicated in the rules.