Patents by Inventor Jianfei Wang

Jianfei Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12358927
    Abstract: Provided are a crystal of a compound of formula (I), salt thereof, a crystal of the salt thereof, and a preparation method for the crystal. Also comprised are applications of the compound and the crystal in preparation of drugs for treating IRAK4-related diseases.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: July 15, 2025
    Assignee: Chia Tai Tianqing Pharmaceutical Group Co., Inc.
    Inventors: Yang Zhang, Jianfei Wang, Haizhong Tan, Yuhai Xing, Jian Li, Shuhui Chen
  • Publication number: 20250213869
    Abstract: A method for detecting atrial tachycardia includes monitoring a total number of historical detection intervals belonging to atrial tachycardia intervals within a set time of a target pacemaker in a tracking mode. If the total number is within a first preset number range threshold an atrioventricular delay interval duration of the target pacemaker is delayed. The method further includes determining whether the total number of the historical detection intervals belonging to the atrial tachycardia intervals within the set time after the atrioventricular delay interval duration of the target pacemaker is adjusted is greater than an upper limit value of the first preset number range threshold. If the total monitored number of the historical detection intervals is greater than the upper limit value of the first preset number range threshold a determination is made that an atrial tachycardia event has occurred.
    Type: Application
    Filed: April 25, 2023
    Publication date: July 3, 2025
    Applicant: CORERHYTHM MEDICAL TECHNOLOGY (HANGZHOU) CO., LTD
    Inventors: Min HUANG, Jianqu XIONG, Guiling LI, Jianfei WANG, Cheng FANG, Lian JIN, Zhen ZHOU
  • Publication number: 20250179087
    Abstract: The present invention disclose novel compounds; methods for the production of the compounds of the invention; pharmaceutical compositions comprising the compounds of the invention; as well as uses and methods for treating a disease mediated by LPAR5 by administering the compounds of the invention. In particular, the compounds of the invention may be used as LPAR5 inhibitors.
    Type: Application
    Filed: March 3, 2023
    Publication date: June 5, 2025
    Inventors: Jianbei XI, Yue LI, Guohuang FAN, Jianfei WANG
  • Patent number: 12322926
    Abstract: A tunable laser assembly housed in a single enclosure and a method of control is described wherein the tunable laser, pump and semiconductor optical amplifier do not share a common optical axis but are all aligned to optical waveguides on an intervening planar lightwave circuit (PLC). Wavelength monitoring circuitry is included on the PLC to enable monitoring and control of the tunable laser center wavelength and optical bandwidth. The design of the PLC does not introduce perturbations into the swept-source laser output spectrum that would cause artifacts in imaging applications such as optical coherence tomography (OCT).
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: June 3, 2025
    Assignee: Thorlabs Quantum Electronics, Inc.
    Inventors: Peter J. S. Heim, John Hryniewicz, Jacob Mertz, Jianfei Wang
  • Publication number: 20250108222
    Abstract: Disclosed in the present invention is a pacing device for preventing occurrence of atrial fibrillation following premature atrial contraction, including: adjusting values of the number M of atrial events and the number N of premature atrial contraction events to control a pacing control process for preventing the occurrence of atrial fibrillation following premature atrial contraction to take place after a single or more than one premature atrial contraction events, and on the basis of a current p-p? interval, an atrial safe pacing interval and an average atrial interval, setting a smooth transition pacing sequence. The smooth transition pacing sequence avoids atrial compensation intervals caused by the premature atrial contraction and avoids occurrence of a “short-long-short” sequence.
    Type: Application
    Filed: April 4, 2023
    Publication date: April 3, 2025
    Inventors: LIAN JIN, MIN HUANG, GUILING LI, JIANFEI WANG, ZHEN ZHOU, JIANQU XIONG
  • Patent number: 12261413
    Abstract: A tunable laser assembly housed in a single enclosure and a method of control is described wherein the tunable laser, pump and semiconductor optical amplifier do not share a common optical axis but are all aligned to optical waveguides on an intervening planar lightwave circuit (PLC). Wavelength monitoring circuitry is included on the PLC to enable monitoring and control of the tunable laser center wavelength and optical bandwidth. The design of the PLC does not introduce perturbations into the swept-source laser output spectrum that would cause artifacts in imaging applications such as optical coherence tomography (OCT).
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: March 25, 2025
    Assignee: Thorlabs Quantum Electronics, Inc.
    Inventors: Peter J. S. Heim, John Hryniewicz, Jacob Mertz, Jianfei Wang
  • Publication number: 20250084097
    Abstract: A series of macrocyclic amide compounds and an application thereof. Specifically disclosed are a compound as represented by formula (V) or a pharmaceutically acceptable salt thereof and an application thereof.
    Type: Application
    Filed: July 15, 2022
    Publication date: March 13, 2025
    Applicant: Medshine Discovery Inc.
    Inventors: Jianfei Wang, Shulun Chen, Guangwen Yang, Yang Zhang, Shuhui Chen
  • Patent number: 12223275
    Abstract: A method of training a model, an electronic device, and a storage medium are provided, which relate to a field of artificial intelligence, and in particular to a field of reinforcement learning, NLP, etc. The method includes: acquiring a dialogue information; obtaining a predicted information based on the dialogue information by using a first intention recognition model, a first recurrent neural network and a first named entity recognition model; obtaining a machine behavior information based on the predicted information by using a first behavior decision model; acquiring a feedback information for the machine behavior; storing at least one of the predicted information, the machine behavior information, or the feedback information as training data in a database; and performing a model optimization training online based on the training data by using a reinforcement learning algorithm, in response to an amount of the training data reaching a preset data amount.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: February 11, 2025
    Assignee: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
    Inventors: Weijie Ren, Jianfei Wang, Cheng Peng
  • Publication number: 20250034121
    Abstract: The disclosure relates to the compounds as GPR183 inhibitors, the methods for preparing these compounds, and the compositions and their uses as treatment or prevention of cancers, autoimmune diseases, pain, and osteoporosis using GPR 183 inhibitors targeted immune cells.
    Type: Application
    Filed: October 17, 2022
    Publication date: January 30, 2025
    Inventors: Jianbei Xi, Guohuang Fan, Jianfei Wang
  • Publication number: 20240352134
    Abstract: The present invention relates to anti-CCR8 antibodies and to methods of using anti-CCR8 antibodies. The anti-CCR8 antibodies described herein are useful for the diagnosis and treatment of diseases mediated by CCR8 and/or CCL1, such as various cancers and neuropathic pain associated with abnormal CCL1/CCR8 axis.
    Type: Application
    Filed: June 24, 2022
    Publication date: October 24, 2024
    Inventors: Guohuang Fan, Jianfei Wang, Juan DU, Na Wang
  • Publication number: 20240254113
    Abstract: Provided are compounds of Formula I which can be used as CD38 inhibitors; methods for the production of the compounds; pharmaceutical compositions comprising the compounds; as well as uses and methods for treating a disease mediated by CD38 by administering the compounds.
    Type: Application
    Filed: April 28, 2022
    Publication date: August 1, 2024
    Inventors: Jianbei Xi, Guohuang Fan, Jianfei Wang, Kin Chiu Fong
  • Publication number: 20240083912
    Abstract: The present invention provides compounds of Formula I which can be used as macrophage migration inhibitory factor (MIF) inhibitors; methods for the production of the compounds of the invention; pharmaceutical compositions comprising the compounds of the invention; as well as uses and methods for treating a disease mediated by MIF by administering the compounds of the invention.
    Type: Application
    Filed: October 27, 2023
    Publication date: March 14, 2024
    Inventors: Gouhuang Fan, Kin Chiu Fong, Hongyu Yang, Jianfei Wang
  • Patent number: 11884682
    Abstract: The present invention provides compounds of Formula I which can be used as macrophage migration inhibitory factor (MIF) inhibitors; methods for the production of the compounds of the invention; pharmaceutical compositions comprising the compounds of the invention; as well as uses and methods for treating a disease mediated by MIF by administering the compounds of the invention.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: January 30, 2024
    Assignee: NANJING IMMUNOPHAGE BIOTECH CO., LTD.
    Inventors: Guohuang Fan, Kin Chiu Fong, Hongyu Yang, Jianfei Wang
  • Publication number: 20230391776
    Abstract: Provided is an amide oxazole compound, in particular a compound, as represented by formula (IV), or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 20, 2021
    Publication date: December 7, 2023
    Inventors: Jianfei WANG, Haizhong TAN, Yang ZHANG, Jian LI, Shuhui CHEN
  • Publication number: 20230219902
    Abstract: Disclosed is a method for preparing a chlorinated compound, and specifically disclosed is a method for preparing a compound represented by formula (I).
    Type: Application
    Filed: June 10, 2021
    Publication date: July 13, 2023
    Inventors: Jianfei WANG, Yang ZHANG, Shuhui CHEN
  • Publication number: 20230159446
    Abstract: The present invention provides compounds of Formula (I) which can be used as CCR8 inhibitors, which can be used as treatment or prevention of cancer using CCR8 inhibitors targeted tumor specific T regulatory cells.
    Type: Application
    Filed: December 23, 2022
    Publication date: May 25, 2023
    Inventors: Guohuang FAN, Hongyu YANG, Kin Chiu FONG, Jianfei WANG
  • Publication number: 20230060905
    Abstract: Provided are a crystal of a compound of formula (I), salt thereof, a crystal of the salt thereof, and a preparation method for the crystal. Also comprised are applications of the compound and the crystal in preparation of drugs for treating IRAK4-related diseases.
    Type: Application
    Filed: January 21, 2021
    Publication date: March 2, 2023
    Inventors: Yang ZHANG, Jianfei WANG, Haizhong TAN, Yuhai XING, Jian LI, Shuhui CHEN
  • Publication number: 20230038589
    Abstract: The present invention provides compounds of Formula (I) which can be used as CCR8 inhibitors, which can be used as treatment or prevention of cancer using CCR8 inhibitors targeted tumor specific T regulatory cells.
    Type: Application
    Filed: July 3, 2020
    Publication date: February 9, 2023
    Applicant: Nanjing Immunophage BioTech Co., Ltd.
    Inventors: Guohuang Fan, Hongyu Yang, Kin Chiu Fong, Jianfei Wang
  • Publication number: 20230002410
    Abstract: Disclosed are a class of compounds having a highly selective inhibition of ROS1, and the use thereof in the preparation of drugs for treating diseases related to abnormal ROS1 kinase expression. Specifically disclosed are compounds represented by formula (IV) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 18, 2020
    Publication date: January 5, 2023
    Inventors: Jianfei WANG, Guangwen YANG, Jikui SUN, Zhihua AO, Peng LI, Yang ZHANG, Qiu LI, Jian LI, Shuhui CHEN
  • Patent number: D1025661
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: May 7, 2024
    Assignee: Huangshan Spring Trading Co., Ltd.
    Inventor: Jianfei Wang