Patents by Inventor Jian-Hwa Guo

Jian-Hwa Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160324735
    Abstract: A topical treatment strip comprising a substrate having two surfaces with a topical composition carried thereupon. The treatment strip can be used to treat two surfaces of subject such as both lips simultaneously. Methods include methods of manufacture and methods of use.
    Type: Application
    Filed: June 17, 2016
    Publication date: November 10, 2016
    Applicant: Wyeth LLC
    Inventor: Jian-Hwa Guo
  • Patent number: 8865202
    Abstract: A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
    Type: Grant
    Filed: February 5, 2004
    Date of Patent: October 21, 2014
    Assignee: LTS LOHMANN Therapie-Systeme AG
    Inventors: Horst Georg Zerbe, Jian-Hwa Guo, Anthony Serino
  • Publication number: 20120114705
    Abstract: A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 10, 2012
    Inventors: Horst Georg ZERBE, Jian-Hwa Guo, Anthony Serino
  • Publication number: 20110027329
    Abstract: A topical treatment strip comprising a substrate having two surfaces with a topical composition carried thereupon. The treatment strip can be used to treat two surfaces of subject as such as both lips simultaneously. Methods include methods of manufacture and methods of use.
    Type: Application
    Filed: May 21, 2010
    Publication date: February 3, 2011
    Applicant: Wyeth LLC
    Inventor: Jian-Hwa GUO
  • Publication number: 20040219210
    Abstract: A polymer or copolymer composition derived from one or more unsaturated carboxylic acids that are cross-linked and nifedipine in conjunction with conventional materials such as fillers, excipients, and optional surface active agents is disclosed. Solid dosage forms of sustained release tablets containing the polymer or copolymer composition can be formed by wet granulation followed by mixing with other tableting ingredients, compression to form a tablet core, and finally coating to form the finished tablets. The polymer or copolymer, as a controlled release agent, can enhance controlled-release properties while meeting acceptable release rates as specified by the USP.
    Type: Application
    Filed: April 22, 2004
    Publication date: November 4, 2004
    Inventor: Jian-Hwa Guo
  • Publication number: 20040191187
    Abstract: A polymeric formulation, and more specifically, a toothpaste formulation, is disclosed containing a highly carboxylated polymer or copolymer derived from one or more unsaturated carboxylic acids in combination with a calcium carbonate abrasive, a galactomannan, and traditional filler materials. The formulation is especially useful where sources of multivalent cations would otherwise cause phase separation and instability of the toothpaste.
    Type: Application
    Filed: January 28, 2004
    Publication date: September 30, 2004
    Inventors: Hong Luo, William Robert Wilber, Jian-Hwa Guo
  • Publication number: 20040156885
    Abstract: A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
    Type: Application
    Filed: February 5, 2004
    Publication date: August 12, 2004
    Inventors: Horst Georg Zerbe, Jian-Hwa Guo, Anthony Serino
  • Patent number: 6762267
    Abstract: The present invention pertains to a method for forming polyacrylic acid granules and granules formed therefrom wherein the granules are flowable, have an increased bulk density relative to the as polymerized polyacrylic acids, and a low amount of dust which is generally characterized herein as particles which pass through a 325 mesh screen. The granules formed by the method of the present invention can be used to prepare controlled release tablets, especially controlled release pharmaceutical tablets. The controlled release properties of the tablets formed from granules prepared according to the present invention are unexpectedly better than tablets prepared from granules formed by other known granulation methods.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: July 13, 2004
    Assignee: Noveon IP Holdings Corp.
    Inventors: Daniel James Adams, David William Weaver, William R. Wilber, Jian-Hwa Guo, Edward S. Greenberg
  • Patent number: 6723781
    Abstract: A blend of one or more crosslinked polymers or copolymers prepared from an olefinically unsaturated polymerizable carboxylic or anhydride monomer and at least one high molecular weight essentially linear polymer prepared from an olefinically unsaturated polymerizable carboxylic acid monomer. The blend is neutralized to typically a low pH, and generally contains a noncovalent, e.g. ionic, crosslinking agent, and a cure rate modifier. The hydrogel blend is capable of containing a large amount of water, has good tack, good adhesion, and can be utilized as an application vehicle having a backing thereon as well as containing various substances such as personal care compounds, pharmaceuticals, active ingredients, and the like. Conversely, the hydrogel blend can be dried and subsequently wetted without substantial loss of properties.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: April 20, 2004
    Assignee: Noveon IP Holdings Corp.
    Inventors: Dean M. Frate, Jian-Hwa Guo
  • Patent number: 6709671
    Abstract: A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: March 23, 2004
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Horst Georg Zerbe, Jian-Hwa Guo, Anthony Serino
  • Publication number: 20030187167
    Abstract: The present invention pertains to a method for forming polyacrylic acid granules and granules formed therefrom wherein the granules are flowable, have an increased bulk density relative to the as polymerized polyacrylic acids, and a low amount of dust which is generally characterized herein as particles which pass through a 325 mesh screen. The granules formed by the method of the present invention can be used to prepare controlled release tablets, especially controlled release pharmaceutical tablets. The controlled release properties of the tablets formed from granules prepared according to the present invention are unexpectedly better than tablets prepared from granules formed by other known granulation methods.
    Type: Application
    Filed: March 31, 2003
    Publication date: October 2, 2003
    Applicant: Noveon IP Holdings Corp.
    Inventors: Daniel James Adams, David William Weaver, William R. Wilber, Jian-Hwa Guo, Edward S. Greenberg
  • Patent number: 6623756
    Abstract: Solid dosage articles such as pharmaceutical tablets for the controlled release of a desired compound such as an active ingredient are directly compressed from a flowable, compressible mixture of the active ingredient, a slightly cross-linked rheology modifying polymer or copolymer, and one or more excipients. The rheology modifying polymer or copolymer is a granulated powder of suitable particle size and is generally made from one or more unsaturated (di)carboxylic acids, half ester thereof, and other optional monomers.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: September 23, 2003
    Assignee: Noveon IP Holdings Corp.
    Inventors: William R. Wilber, Jian-Hwa Guo, Edward S. Greenberg
  • Patent number: 6623754
    Abstract: A directly-compressed, controlled release tablet contains N-acetyl cysteine as the active ingredient.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: September 23, 2003
    Assignee: Noveon IP Holdings Corp.
    Inventors: Jian-Hwa Guo, William Robert Wilber
  • Patent number: 6592887
    Abstract: A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: July 15, 2003
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Horst Georg Zerbe, Jian-Hwa Guo, Anthony Serino
  • Patent number: 6572889
    Abstract: A polymer or copolymer composition derived from one or more unsaturated carboxylic acids that is cross-linked and carbamazepine in conjunction with conventional materials such as fillers, excipients, and surface active agents is disclosed. Solid dosage forms of immediate and sustained release tablets containing the polymer or copolymer composition can be formed by wet granulation or wet granulation followed by blending with direct compression ingredients. The polymer or copolymer, as a controlled release agent, can enhance controlled-release properties while meeting acceptable release rates as specified by the USP.
    Type: Grant
    Filed: March 7, 2002
    Date of Patent: June 3, 2003
    Assignee: Noveon IP Holdings Corp.
    Inventor: Jian-Hwa Guo
  • Publication number: 20030003148
    Abstract: A directly-compressed, controlled release tablet contains N-acetyl cysteine as the active ingredient.
    Type: Application
    Filed: May 21, 2001
    Publication date: January 2, 2003
    Inventors: Jian-Hwa Guo, William Robert Wilber
  • Publication number: 20020150544
    Abstract: A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
    Type: Application
    Filed: June 5, 2002
    Publication date: October 17, 2002
    Inventors: Horst Georg Zerbe, Jian-Hwa Guo, Anthony Serino
  • Publication number: 20020127190
    Abstract: A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
    Type: Application
    Filed: May 14, 2002
    Publication date: September 12, 2002
    Inventors: Horst Georg Zerbe, Jian-Hwa Guo, Anthony Serino
  • Patent number: 6358525
    Abstract: A pharmaceutical composition has a blend of at least first and second components and a medicament in a sufficient amount to be therapeutic where the first component is hydroxypropylcellulose (HPC) and the second component is at least one other polymer selected from the group consisting of methylcellulose (MC), ethylhydroxyethylcellulose (EHEC), hydroxyethylmethylcellulose (HEMC), hydrophobically modified hydroxyethylcellulose (HMHEC), hydrophobically modified ethylhydroxyethylcellulose (HMEHEC), carboxymethylhydroxyethylcellulose (CMHEC), carboxymethyl hydrophobically modified hydroxyethylcellulose (CMHMHEC), guar, pectin, carrageenan, agar, algin, gellan gum, acacia, starch and modified starches, co-polymers of carboxyvinyl monomers, co-polymers of acrylate or methacrylate monomers, mono- and co-polymers of oxyethylene and oxypropylene and mixtures thereof and a medicament in a sufficient amount to be therapeutic, with the proviso that low-substituted hydroxypropylcellulose (L-HPC) is excluded from said firs
    Type: Grant
    Filed: June 30, 1999
    Date of Patent: March 19, 2002
    Assignee: Hercules Incorporated
    Inventors: Jian Hwa Guo, George William Skinner
  • Publication number: 20010046511
    Abstract: A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
    Type: Application
    Filed: August 13, 2001
    Publication date: November 29, 2001
    Inventors: Horst Georg Zerbe, Jian-Hwa Guo, Anthony Serino