Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid. A blood indicator panel (BIP) device is provided for rapid blood volume measurement (in mls.) in a fluid (e.g., a collected surgical fluid). An RBC flocculant (e.g., polyDADMAC) may be used to induce more rapid sedimentation of red blood cells from the fluid. A series of markings is provided on one side of the BIP, each marking corresponding to a volume of blood (in milliliters). The markings are calculated by use of a formula: Vb=Vm/(Hct×1.2), wherein Hct is an average blood hematocrit, and 1.2 is an RBC packing ratio value for a conventional 1,200 ml waste collection canister (1.2 alternatively referenced as “?”). The BIP does not employ centrifugation, electronic image transmission or analysis, is temperature independent, and is accurate to about +/?10%.

Abstract: The design, fabrication and applications of a three-dimensional (3D) bioreactor with filled void structure. The bioreactor comprises non-random voids filled with a non-random internal structure where the voids are interconnected through non-random pore channels. The 3D bioreactor provides a three-dimensional surface area for cell adherence and growth.

Abstract: Disclosed are methods, materials and devices for approximating blood volume in a fluid obtained from a subject, such as blood in a biological fluid collected during a surgical procedure. In particular applications, methods of estimating blood volume in a sample as part of a method for estimating blood loss from a subject are provided. The methods provide for a much accelerated technique for determining blood volume and/or packed red blood cell units in a sample (within about 5-10 minutes). The method and devices (canisters) may include a red blood cell (RBC) flocculant, such as polyDADMAC, and employ a formula that includes a value for an approximate blood hematocrit, and an approximate red blood cell packing ratio (“?”) for a collection container.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

Abstract: New data class generation is provided. A dimension score is generated for each respective dimension of a plurality of predefined dimensions as relating to column attributes of a data asset while performing a static reference data analysis of the data asset. The dimension score of each respective dimension is added together to obtain a total dimension score for the data asset. It is determined whether the total dimension score of the data asset is greater than a predefined minimum dimension score threshold level. The data asset is identified as new static reference data in response to determining that the total dimension score of the data asset is greater than the predefined minimum dimension score threshold level. A new data class is generated based on the new static reference data.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. In particular applications, methods of estimating blood loss from a subject are provided. The method and devices may include a RBC flocculant, such as polyDADMAC, and provide for an approximate blood hematocrit for a selected type of animal, as well as provide for a calculated RBC packing ratio corresponding to the collection device receiving the fluid. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood cell sedimentation volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that may include a RBC flocculant, for use in approximating blood volume in a fluid.

Abstract: Described herein is a beads-free bioprocessor as an automated and cost-effective T cell processing and manufacturing platform. T cells are a core component in CAR T cell therapies for cancer treatment, but are difficult to manufacture to scale in clinically relevant quantities. The 3D bioprocessor provides an alternative device that is scalable, beads-free, easy-to-use, and cost-effective for using CAR T cell therapy in cancer immunotherapy. Besides CAR T cell application, this platform technology has potential for many other applications such as cancer cell isolation.

Abstract: An approach is disclosed that receives a new ETL job. The job includes a number of intermediate database files descriptors corresponding to a plurality of intermediate database files that are used to accomplish the new ETL. A new data lineage graph is created that pertains to the new ETL job. The new data lineage graph is compared to a number of existing data lineage graphs with each of the existing data lineage graphs corresponding to an existing ETL job. The approach substitutes existing database files found in the existing data lineage graphs for one or more intermediate database files found in the new data lineage graph. The new ETL job is then run by utilizing the substituted database files, the result being a new final database file.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices may include a RBC flocculant, such as polyDADMAC, and provide for an approximate blood hematocrit for a selected type of animal, as well as provide for a calculated RBC packing ratio corresponding to the collection device receiving the fluid. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood cell sedimentation volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that may include a RBC flocculant, for use in approximating blood volume in a fluid.

Abstract: Methods, systems, computer program products for determining the source of activity during interaction with a user interface are provided. The method comprises selecting one or more input devices from a plurality of available input devices coupled to the user interface and receiving respective measurements for the selected one or more input devices. Based on the received respective measurements, respective feature vectors for the one or more input devices are generated and then inputted to a pre-defined regression model. Then, the source of activity is determined based on a result received from the regression model.

Abstract: Design, fabrication and applications of three-dimensional (3D) bioreactor for cell expansion and cell secreted substance production. The bioreactors have relatively low levels of potentially cytotoxic compounds, can be coated with substituted or unsubstituted poly(p-xylene) type coatings and can also be separately formed from liquid crystal photopolymerizable monomers.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices may include the use of an RBC flocculant, for example polyDADMAC, and an approximate blood hematocrit from the type of animal blood being evaluated, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal blood hematocrit, and a calculated RBC packing ratio “ii” value for the collection device. A collection device with a BIP is disclosed. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. In particular applications, methods of estimating blood loss from a subject are provided. The method and devices may include a RBC flocculant, such as polyDADMAC, and provide for an approximate blood hematocrit for a selected type of animal, as well as provide for a calculated RBC packing ratio corresponding to the collection device receiving the fluid. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood cell sedimentation volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that may include a RBC flocculant, for use in approximating blood volume in a fluid.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices may include the use of an RBC flocculant, for example polyDADMAC, and an approximate blood hematocrit from the type of animal blood being evaluated, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal blood hematocrit, and a calculated RBC packing ratio “?” value for the collection device. A collection device with a BIP is disclosed. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

Abstract: An approach is provided that retrieves fingerprint configuration sets corresponding to a received data source and uses the configuration sets to generate fingerprints that correspond to the data source. These fingerprints are compared to a number of fingerprints that are stored in a repository. If a match is found, then the data quality configuration set is retrieved from the repository and used to perform a data quality analysis. On the other hand, if a match is not found, then one of the configuration sets is selected to perform the data quality analysis on the received data source and the repository is updated so that the selected fingerprint configuration set corresponds to the received data source.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

Abstract: Devices and methods suitable for cell separation. The devices herein include non-random voids interconnected through non-random pores and/or non-random solid geometrical structures optionally connected through solid non-random interconnecting elements. Such devices are preferably suitable for affinity-based cell isolation techniques which rely upon binding interactions.

Abstract: Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. In particular applications, methods of estimating blood loss from a subject are provided. The method and devices may include a RBC flocculant, such as polyDADMAC, and provide for an approximate blood hematocrit for a selected type of animal, as well as provide for a calculated RBC packing ratio corresponding to the collection device receiving the fluid. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood cell sedimentation volume, the average animal type hematocrit, and a calculated RBC packing ratio “?” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that may include a RBC flocculant, for use in approximating blood volume in a fluid.