Abstract: Disclosed are a class of compounds having a new structure as an ATR inhibitor, and a stereoisomer, an optical isomer, a pharmaceutical salt, a prodrug and a solvate thereof. An in-vitro enzyme inhibitory activity study shows that the compounds have a strong inhibitory effect on an ATR enzyme, and can be used as prospecting compounds for treating ATR-mediated diseases.

Abstract: The present disclosure provides compounds that can inhibit the type III secretion system (TTSS) to decrease the pathogenesis of gram-negative bacteria. These compounds may have wide applications for treating bacteria diseases caused by gram-negative bacteria in a host species, including but not limited to, plants and animals. The present invention further relates to compositions that inhibit pathogenesis of gram-negative bacteria without killing the bacteria. Methods relating to preventing and/or treating infection of a host species by bacterial pathogens are also provided herein.

Abstract: Provided include a microfluidic device capable of performing reagent exchange, a gas-flow control device, a cell reaction module, and a device for preparing cell samples, such as a single-cell sample, and method of use thereof.

Abstract: A method for adjusting a window includes: in response to detecting a first operation for triggering a specified position of the window, obtaining at least one candidate proportion of the current window based on a type of the window, and obtaining an actual proportion of the window that varies with the first operation; in response to detecting a second operation for stopping triggering the window, obtaining a difference between the at least one candidate proportion and the actual proportion, and determining a candidate proportion with the smallest difference as a target proportion; and adjusting a proportion of the window from the actual proportion to the target proportion.

Abstract: A method is provided for obtaining display data. The method includes: obtaining rendering data corresponding to an application program surface; obtaining, in response to detecting an operation of adjusting a dimension of the application program surface, a transformation coefficient corresponding to the application program surface, where the transformation coefficient is a scale value between a dimension of the application program surface after adjustment and a dimension before adjustment; and obtaining display data of a corresponding masking layer of the application program surface according to the transformation coefficient and the rendering data.

Abstract: A method for taping a wafer is disclosed. A wafer taping device comprising a wafer stage is provided. A wafer is mounted and secured on the wafer stage. A tape is delivered along a first direction over the wafer. The tape is forced into adhesion with a surface of the wafer in a non-contact manner. The tape is cut along a perimeter of the wafer.

Abstract: A method for adjusting a window includes: in response to detecting a first operation for triggering a specified position of the window, obtaining at least one candidate proportion of the current window based on a type of the window, and obtaining an actual proportion of the window that varies with the first operation; in response to detecting a second operation for stopping triggering the window, obtaining a difference between the at least one candidate proportion and the actual proportion, and determining a candidate proportion with the smallest difference as a target proportion; and adjusting a proportion of the window from the actual proportion to the target proportion.

Abstract: A method is provided for obtaining display data. The method includes: obtaining rendering data corresponding to an application program surface; obtaining, in response to detecting an operation of adjusting a dimension of the application program surface, a transformation coefficient corresponding to the application program surface, where the transformation coefficient is a scale value between a dimension of the application program surface after adjustment and a dimension before adjustment; and obtaining display data of a corresponding masking layer of the application program surface according to the transformation coefficient and the rendering data.

Abstract: A method for taping a wafer is disclosed. A wafer taping device comprising a wafer stage is provided. A wafer is mounted and secured on the wafer stage. A tape is delivered along a first direction over the wafer. The tape is forced into adhesion with a surface of the wafer in a non-contact manner. The tape is cut along a perimeter of the wafer.

Abstract: A method for taping a wafer is disclosed. A wafer taping device comprising a wafer stage is provided. A wafer is mounted and secured on the wafer stage. A tape is delivered along a first direction over the wafer. The tape is forced into adhesion with a surface of the wafer in a non-contact manner. The tape is cut along a perimeter of the wafer.

Abstract: A heating mode control method of an air conditioner, comprises: obtaining an indoor temperature and calculating the difference between the indoor temperature and an indoor target temperature to obtain an indoor temperature difference as air conditioner running at heating mode; performing a coil temperature control process as the indoor temperature difference in a set indoor temperature difference range, wherein the coil temperature control process including: obtaining an indoor coil temperature and controlling the frequency of the compressor according to the indoor coil temperature and a coil target temperature. The application of the method can achieve the purpose of improving the heating effect by increasing the outlet air temperature, thus improving the heating performance of an air-conditioner.

Abstract: A method for taping a wafer is disclosed. A wafer taping device comprising a wafer stage is provided. A wafer is mounted and secured on the wafer stage. A tape is delivered along a first direction over the wafer. The tape is forced into adhesion with a surface of the wafer in a non-contact manner. The tape is cut along a perimeter of the wafer.

Abstract: A heating mode control method of an air conditioner, comprises: obtaining an indoor temperature and calculating the difference between the indoor temperature and an indoor target temperature to obtain an indoor temperature difference as air conditioner running at heating mode; performing a coil temperature control process as the indoor temperature difference in a set indoor temperature difference range, wherein the coil temperature control process including: obtaining an indoor coil temperature and controlling the frequency of the compressor according to the indoor coil temperature and a coil target temperature. The application of the method can achieve the purpose of improving the heating effect by increasing the outlet air temperature, thus improving the heating performance of an air-conditioner.

Abstract: This invention relates to the cosmetic use of at least one compound of formula (I) wherein A1 is the radical corresponding to D- or L-Ser A2 is the radical corresponding to D- or L-Asp or Glu, A3 is the radical corresponding to D- or L-Lys, Arg or Orn, A4 is the radical corresponding to D- or L-pro, R1, R2 and R3 are as defined in the claims as anti-aging and restructuring agents.

Abstract: The invention relates to a compound of the formula (I) in which: R1, R2 and R3 are independently a methoxy group optionally substituted by one or more fluorine atoms; R4 is a hydrogen atom; R5 and R6 are identical and each represent a hydrogen or fluorine atom; A is a cycle selected from the group including aryl and heteroaryl groups, wherein said groups can be substituted.

Abstract: The present invention relates to compounds of formula (I) below in which: —R1 and R3 represent, independently of one another, a methoxy group optionally substituted by one or more fluorine atoms, —R2 and R4 represent, independently of one another, a hydrogen atom or a methoxy group optionally substituted by one or more fluorine atoms, —A represents a ring chosen from the group comprising aryl and heteroaryl groups, said ring possibly being substituted by or fused to a heterocycle, —X represents a nitrogen atom or a CH group, and —Z1 represents a hydrogen atom or a halogen atom, preferably fluorine, and —Z2 represents a hydrogen atom, a halogen atom, preferably fluorine, a C1 to C4 alkyl group, an aryl group or a —CN, —SO2NR12R13, —SO2R9, —COOR15 or —COR15 group, and also to the pharmaceutically acceptable salts thereof, the isomers thereof and the prodrugs thereof.

Abstract: The invention relates to a compound of the formula (I) in which: R1, R2 and R3 are independently a methoxy group optionally substituted by one or more fluorine atoms; R4 is a hydrogen atom; R5 and R6 are identical and each represent a hydrogen or fluorine atom; A is a cycle selected from the group including aryl and heteroaryl groups, wherein said groups can be substituted.

Abstract: This invention relates to the cosmetic use of at least one compound of formula (I) wherein A1 is the radical corresponding to D- or L-Ser A2 is the radical corresponding to D- or L-Asp or Glu, A3 is the radical corresponding to D- or L-Lys, Arg or Orn, A4 is the radical corresponding to D- or L-pro, R1, R2 and R3 are as defined in the claims as anti-aging and restructuring agents.

Abstract: A method for forming carbon nanostructures is disclosed. The method includes the steps of: (a) synthesising a microporous template material comprising crystals having no dimension greater than about 2 ?m, (b) heating the crystals in the presence of an inert gas or a mixture of an inert gas and a carbon-containing gas at a temperature of between 500° C. and 900° C., and (c) recovering carbon nanostructures by washing the heated crystals in an acid to remove the template material.