Patents by Inventor Jian-Min Fu

Jian-Min Fu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted azepino[4,5b]indoline derivatives
    Patent number: 6828314
    Abstract: The invention provides compounds of Formula (I): wherein R1-R4, p and q have any of the values described in the specification, as well as pharmaceutical salts thereof, and pharmaceutical compositions containing such compounds or salts. The compounds and salts are 5-HT ligands and are useful for treating diseases, disorders, and/or conditions in a mammal wherein activity of a 5-HT receptor is implicated. The compounds and salts are particularly useful for treating diseases of the central nervous system.
    Type: Grant
    Filed: March 20, 2003
    Date of Patent: December 7, 2004
    Assignee: Pfizer
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-min Fu, Eric Jon Jacobsen, William W. McWhorter, Jr., Jeanette K. Morris, Donald Joseph Rogier
  • Pyrrolo[1,2-b]pyridazine compounds
    Publication number: 20040242587
    Abstract: This invention relates to substituted pyrrolo[1,2-b]pyridazine compounds of Formula I, 1
    Type: Application
    Filed: May 5, 2004
    Publication date: December 2, 2004
    Applicant: Pfizer Inc
    Inventor: Jian-Min Fu
  • Pyrrolo[1,2-B]pyridazine compounds and their uses
    Publication number: 20040209887
    Abstract: Disclosed are novel CRF receptor antagonists and their use as treatment of a variety of disorders, including disorders manifesting hypersecretion of CRF or associated with CRF or CRF receptors, such as anxiety, and depression.
    Type: Application
    Filed: March 12, 2004
    Publication date: October 21, 2004
    Applicant: Pfizer Inc
    Inventor: Jian-min Fu
  • Pyrrolo[1,2-B]pyridazine compounds and their uses
    Publication number: 20040204415
    Abstract: Disclosed are novel CRF receptor antagonists and their use as treatment of a variety of disorders, including disorders manifesting hypersecretion of CRF or associated with CRF or CRF receptors, such as anxiety, and depression.
    Type: Application
    Filed: March 12, 2004
    Publication date: October 14, 2004
    Applicant: Pfizer Inc
    Inventor: Jian-min Fu
  • Pyrrolo[1,2-B]pyridazine compounds and their uses
    Publication number: 20040204414
    Abstract: Disclosed are novel CRF receptor antagonists and their use as treatment of a variety of disorders, including disorders manifesting hypersecretion of CRF or associated with CRF or CRF receptors, such as anxiety, and depression.
    Type: Application
    Filed: March 12, 2004
    Publication date: October 14, 2004
    Applicant: Pfizer Inc
    Inventor: Jian-min Fu
  • Arylsulphonyl substituted-tetrahydro-and hexahydro-carbazoles
    Publication number: 20040162332
    Abstract: The invention provides compounds of formula I for use in treating conditions in which 5-HT6 receptors are involved such as in anxiety, depression, schizophrenia, Alzheimer's disease, stress-related disease, panic, a phobia, obsessive compulsive disorder, obesity, post-traumatic stress syndrome, epilepsy, and other CNS disorders.
    Type: Application
    Filed: February 12, 2004
    Publication date: August 19, 2004
    Applicant: Pharmacia & Upjohn Company
    Inventor: Jian-Min Fu
  • Pyrrrolo[1,2-b]pyridazine compounds and their uses
    Publication number: 20040138221
    Abstract: Disclosed are novel CRF receptor antagonists and their use as treatment of a variety of disorders, including disorders manifesting hypersecretion of CRF or associated with CRF or CRF receptors, such as anxiety, and depression.
    Type: Application
    Filed: October 9, 2003
    Publication date: July 15, 2004
    Inventor: Jian-Min Fu
  • Substituted 1,4-pyrazine derivatives
    Publication number: 20040116444
    Abstract: Substituted aryl 1,4-pyrazine derivatives and their use in treating anxiety disorders, depression and stress related disorders are disclosed.
    Type: Application
    Filed: August 27, 2003
    Publication date: June 17, 2004
    Inventors: Jeffrey W. Corbett, Jian-Min Fu, Michael Dalton Ennis, Kristine E. Frank, Robert Louis Hoffman, Patrick R. Verhoest
  • Arylsulphonyl substituted-tetrahydro- and hexahydro-carbazoles
    Patent number: 6727274
    Abstract: The invention provides compounds of formula I for use in treating conditions in which 5-HT6 receptors are involved such as in anxiety, depression, schizophrenia, Alzheimer's disease, stress-related disease, panic, a phobia, obsessive compulsive disorder, obesity, post-traumatic stress syndrome, epilepsy, and other CNS disorders.
    Type: Grant
    Filed: October 8, 2002
    Date of Patent: April 27, 2004
    Assignee: Pharmacia & Upjohn Company
    Inventor: Jian-Min Fu
  • Substituted pyrazine derivatives
    Publication number: 20040053941
    Abstract: The present invention provides substituted pyrazine derivatives of Formula I, 1
    Type: Application
    Filed: April 17, 2003
    Publication date: March 18, 2004
    Inventors: Jeffrey W. Corbett, Michael Dalton Ennis, Kristine E. Frank, Jian-Min Fu, Robert Louis Hoffman, Patrick R. Verhoest
  • Novel pyrazolo[1,5-a]pyridine derivatives and their use as neurotransmitter modulators
    Publication number: 20040002511
    Abstract: The present invention relates to novel pyrazolo[1,5-a]pyridine derivatives of general formula I: 1
    Type: Application
    Filed: March 12, 2003
    Publication date: January 1, 2004
    Inventor: Jian-Min Fu
  • Substituted azepino[4,5b]indoline derivatives
    Publication number: 20030225058
    Abstract: The invention provides compounds of Formula (I): 1
    Type: Application
    Filed: March 20, 2003
    Publication date: December 4, 2003
    Applicant: Pharmacia & UpJohn Company
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-Min Fu, Eric Jon Jacobsen, William W. McWhorter, Jeanette K. Morris, Donald Joseph Rogier
  • Substituted azepino[4,5b]indole derivatives
    Publication number: 20030220321
    Abstract: Disclosed are compounds of Formula (I): 1
    Type: Application
    Filed: March 20, 2003
    Publication date: November 27, 2003
    Applicant: Pharmacia & UpJohn Company
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-Min Fu, William W. McWhorter, Jeanette K. Morris, Donald Joseph Rogier, Eric Jon Jacobsen
  • Azepino[4,5-b]pyrano[3,2-e]indoles
    Publication number: 20030216378
    Abstract: The invention provides a compound of formula (I): 1
    Type: Application
    Filed: January 6, 2003
    Publication date: November 20, 2003
    Inventor: Jian-min Fu
  • Substituted pyrimidinones and pyrimidinthiones
    Publication number: 20030195222
    Abstract: This invention relates to substituted pyrimidinone and pyrimidithione derivatives that bind with high affifnity to CRF1 receptors, including human CRF1 receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety disorders, and depression and stress related disorders.
    Type: Application
    Filed: February 20, 2003
    Publication date: October 16, 2003
    Inventors: Jian-Min Fu, Jeffrey W. Corbett, Michael Dalton Ennis, Kristine E. Frank, Robert Louis Hoffman, Patrick R. Verhoest
  • Therapeutic compounds
    Publication number: 20030181485
    Abstract: The present invention provides compounds, for example, of formula (I): 1
    Type: Application
    Filed: February 27, 2003
    Publication date: September 25, 2003
    Inventor: Jian-Min Fu
  • Therapeutic compounds
    Publication number: 20030149024
    Abstract: The present invention provides compounds of Formula I: 1
    Type: Application
    Filed: November 26, 2002
    Publication date: August 7, 2003
    Inventor: Jian-Min Fu
  • Substituted aryl 1,4-pyrazine derivatives
    Publication number: 20030144297
    Abstract: Substituted aryl 1,4-pyrazine derivatives and their use in treating anxiety disorders, depression and stress related disorders are disclosed.
    Type: Application
    Filed: November 15, 2002
    Publication date: July 31, 2003
    Inventors: Patrick R. Verhoest, Robert Louis Hoffman, Jeffrey W. Corbett, Michael Dalton Ennis, Kristine E. Frank, Jian-Min Fu
  • Substituted azepino[4,5b]indoline derivatives
    Patent number: 6586421
    Abstract: The invention provides compounds of Formula (I): wherein R1-R4, p and q have any of the values described in the specification, as well as pharmaceutical salts thereof, and pharmaceutical compositions containing such compounds or salts. The compounds and salts are 5-HT ligands and are useful for treating diseases, disorders, and/or conditions in a mammal wherein activity of a 5-HT receptor is implicated. The compounds and salts are particularly useful for treating diseases of the central nervous system.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: July 1, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-min Fu, Eric Jon Jacobsen, William W. McWhorter, Jr., Jeanette K. Morris, Donald Joseph Rogier
  • Substituted azepino[4,5b]indole derivatives
    Patent number: 6583135
    Abstract: Disclosed are compounds of Formula (I): wherein R1-R4, p and q have any of the values described in the specification, as well as pharmaceutical salts thereof, and pharmaceutical compositions containing such compounds or salts. The compounds and salts are 5-HT ligands and are useful for treating diseases, disorders, and/or conditions in a mammal wherein activity of a 5-HT receptor is implicated. The compounds and salts are particularly useful for treating diseases of the central nervous system.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: June 24, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-min Fu, William W. McWhorter, Jr., Jeanette K. Morris, Donald Joseph Rogier, Eric Jon Jacobsen