Abstract: This disclosure relates to VIP antagonist for uses in managing the treatment or prevention of cancer and viral infections. In certain embodiments, this disclosure relates to chimeric variants of VIP antagonists, as peptides disclosed herein, and pharmaceutical composition comprising the same. In certain embodiments, this disclosure contemplates methods of stimulating immune cells to target cancer by mixing immune cells in vitro with peptides disclosed herein and further administering an effective amount of stimulated immune cells to a subject in need of cancer treatment.

Abstract: The present invention relates generally to methods and systems that can be used to analyse the mouth condition of an individual. The methods and systems can be used in the identification of an oral condition or disease to provide a personalised holistic treatment care plan for the individual. More particularly, the present invention relates to methods and systems that employ artificial intelligence capabilities for generating a treatment plan for an identified oral condition or disease.

Abstract: An auto-line-division system for handwriting manuscript for line-division of a handwriting manuscript from an electronic handwriting input panel is provided. Generally, in writing, various conditions will generate, such too large or too small words, isolation words, reversal strokes, etc. The system could process these problems in writing based on the setting of a standard line height and a standard line width. The edges and features in division of lines are detected and some values are calculated for correction of the line division so that efficiency of line division is 10 promoted. Another, problems induced in the first line division is taken into consideration, and the problem of multiple lines due to mistake line division can be further correct to one single line. These problems could is corrected so as to promote the accuracy in line division.

Abstract: A surface-treated copper foil includes a bulk copper foil and a first surface treatment layer. The first surface treatment layer is disposed on a first surface of the bulk copper foil and includes a roughening layer, where the outermost surface of the first surface treatment layer is a treating surface of the surface-treated copper foil. The material volume (Vm) of the treating surface is 0.06 to 1.45 ?m3/?m2, and the five-point peak height (S5p) of the treating surface is 0.15 to 2.00 ?m.

Abstract: A device for combining different colors on a computer screen by using an electronic pen includes: an electronic pen having a pen head; a palette capable of being displayed in a screen of a display; the palette including a plurality of color sections of various colors; a touch detector serving to detect a contact angle and pressure of the pen head touching one color section of the palette for determining an amount of a dye and the hue of the color touched; a touch converter serving for converting the angle and the pressure to a hue and an amount of dye so that when the electronic pen is used to writer or draw, the output from the pen head having the color; a color combiner used to mix different colors of the color sections which are touched by the pen head continuously so as to obtain a mixing color.

Abstract: A system of automatically monitoring an electronic billboard to immediately responding a production abnormality and a method thereof are disclosed. In the system, a monitoring device performs an image pattern analysis on a monitoring image to analyze at least one analysis area, and captures the at least one analysis area as a to-be-analyzed image; at least one image analysis method is set to transform the to-be-analyzed image into an image characteristic according to an image pattern of the to-be-analyzed image. When a comparison between the image characteristic and a preset characteristic indicates an abnormality, a monitoring device generates, records and transmits a warning message and/or issues an alarm, thereby achieving the technical effect of automatically monitoring the electronic billboard and immediately responding a production abnormality.

Abstract: A handwriting numbered musical notation recognition system includes: a coding rules database; a music file database for storing a large numbers of music expression files which are collected and edited by computer used formats; a conversion unit for converting music expression files into numbered musical notation files; a handwriting database for storing relations between music symbols and handwriting trace data for numbered musical notations, and a handwriting combination unit connected to the handwriting trace database and the numbered musical notation coding sequences database; and a handwriting numbered musical notation recognition model used for recognition of the handwriting sequence. The music creation can be easily retained by electronic forms, while the creators still can create his (or her) music creations by handwriting. Furthermore, the recognition of the present invention supports the use of MusicXML formats, MIDI formats, or other computer formats.

Abstract: This disclosure relates to VIP antagonist for uses in managing the treatment or prevention of cancer and viral infections. In certain embodiments, this disclosure relates to chimeric variants of VIP antagonists, as peptides disclosed herein, and pharmaceutical composition comprising the same. In certain embodiments, this disclosure contemplates methods of stimulating immune cells to target cancer by mixing immune cells in vitro with peptides disclosed herein and further administering an effective amount of stimulated immune cells to a subject in need of cancer treatment.

Abstract: This technology relates to a method of isolating adipose-derived cell lines from an animal, a method of isolating adipocytes from an animal, and isolated adipose-derived cell lines thereof.

Abstract: A method for forming soluble polymer is provided. The method includes polymerizing a dianhydride monomer, a diamine monomer, and solvent to form soluble polymer. The dianhydride monomer includes 4,4?-4,4?-oxydiphthalic anhydrid, 3,3?,4,4?-biphenyltetracarboxylic dianhydride, and 4,4?-(Hexafluoroisopropylidene) diphthalic anhydride. The diamine monomer includes 3,4?-oxydianiline, 2,2?-Bis(trifluoromethyl)benzidine, and 3,3?-dimethylbenzidine.

Abstract: A method for estimating refrigerant charge for an HVACR system is provided. The method includes obtaining one or more system parameters during operation. The one or more system parameters include at least one of compressor suction superheat, system mass flow, expansion device mass flow or opening degree, compressor suction saturated temperature, and compressor discharge saturated temperature. The method also includes conducting a regression analysis on the one or more system parameters to determine one or more predictive parameters for estimating the refrigerant charge. The method further includes determining a predictive model based on regression analysis. The predictive model establishes a relationship between the refrigerant charge and the one or more predictive parameters. Also the method includes estimating the refrigerant charge based on the predictive model.

Abstract: This disclosure relates to compositions and methods of reversing senescence in T cells by interrupting vasoactive intestinal peptide (VIP) signalling and/or inhibiting phosphatidylinositol-3-kinase (PI3 kinase) inhibitor signalling and uses in managing cancer and chronic viral infections. In certain embodiments, the disclosure contemplates methods of reversing T cell senescence by mixing T cell in vitro with an agent that prevents VIP from interacting with VIP receptors and/or a PI3 Kinase inhibitor. In certain embodiments, the disclosure contemplates the expansion of senescent T cells by mixing with a PI3 kinase inhibitor, an agent that block VIP and VIP receptor signalling, a VIP degrading enzyme, and combinations thereof.

Abstract: Disclosed are VIP-R antagonists for uses in managing the treatment or prevention of cancer and viral infections. In certain embodiments, this disclosure relates to chimeric variants of VIP-R antagonists, as peptides disclosed herein, and pharmaceutical composition comprising the same. In certain embodiments, this disclosure contemplates methods of treating subjects with cancer or infection with VIP-R antagonists or stimulating immune cells to target cancer by mixing immune cells in vitro with peptides disclosed herein and further administering an effective amount of stimulated immune cells to a subject in need of cancer treatment.

Abstract: Disclosed is an attachment for a hair care appliance that has an air inlet end for receiving an airflow from the appliance, an air outlet end for emitting the airflow from the attachment, a wall defining and extending about an airflow path for the airflow and a noise attenuation member surrounded by the wall. The noise attenuation member is configured to guide the airflow along at least part of the airflow path.

Abstract: A haircare appliance includes a pressure sensor for generating a pressure signal indicative of air pressure within an airflow path, the pressure sensor being upstream of an airflow generator. A controller is configured to estimate, based at least partly on the pressure signal, a blockage factor corresponding to an amount by which the airflow path is blocked. When the estimated blockage factor exceeds a blockage warning threshold, a warning indicative of a partial blockage is output. When the estimated blockage factor exceeds a critical threshold, the critical threshold being higher than the blockage warning threshold, a power output of at least one component of the haircare appliance is turned off or reduced.

Abstract: A power converter includes an upper-gate circuit, a lower-gate circuit, an inductor, a first current sensor, a second current sensor, a weight adjustment circuit, and a PWM (Pulse Width Modulation) controller. The upper-gate circuit receives an input voltage. The lower-gate circuit is coupled to a ground node. The upper-gate circuit and the lower-gate circuit are operated according to the PWM voltage. The inductor is coupled to the upper-gate circuit and the lower-gate circuit. The first current sensor monitors the upper-gate circuit, so as to generate a first detection current. The second current sensor monitors the lower-gate circuit, so as to generate a second detection current. The weight adjustment circuit generates a control current according to the first detection current and the second detection current. The PWM controller generates the PWM voltage according to the control current.

Abstract: This disclosure relates to compositions and methods of reversing senescence in T cells by interrupting vasoactive intestinal peptide (VIP) signaling and/or inhibiting phosphatidylinositol-3-kinase (PI3 kinase) inhibitor signaling and uses in managing cancer and chronic viral infections. In certain embodiments, the disclosure contemplates methods of reversing T cell senescence by mixing T cell in vitro with an agent that prevents VIP from interacting with VIP receptors and/or a PI3 Kinase inhibitor. In certain embodiments, the disclosure contemplates the expansion of senescent T cells by mixing with a PI3 kinase inhibitor, an agent that block VIP and VIP receptor signaling, a VIP degrading enzyme, and combinations thereof.

Abstract: Provided herein are methods of using niflumic acid and derivatives thereof for treating a disease or condition associated with elevated serum uric levels in a subject. The methods include administering to the subject an effective amount of a pharmaceutical composition as described herein. The disease or condition associated with elevated serum uric levels can include, for example, gout, hyperuricemia, or cardiovascular disease. Also provided herein are methods of reducing serum uric acid levels in a subject and methods for inhibiting xanthine oxidase activity in a cell. Novel pharmaceutical compositions are also provided herein.

Abstract: An electronic device is provided. The electronic device includes a substrate, a plurality of first pads, a plurality of second pads, a first data line and a touch signal line. The substrate has a first bonding area and a second bonding area. The first pads are disposed in the first bonding area and arranged along a first direction. The second pads are disposed in the second bonding area and arranged along a second direction. There is an included angle between the first direction and the second direction. The first data line is disposed on the substrate and electrically connected to at least one of the first pads or the second pads. The touch signal line is disposed on the substrate and electrically connected to at least another one of the first pads or the second pads. The first data line at least partially overlaps the touch signal line.