Patents by Inventor Jian Ni

Jian Ni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically modified non-human animal with human or chimeric TIM-3
    Patent number: 11240995
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric (e.g., humanized) T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), and methods of use thereof.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: February 8, 2022
    Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
    Inventors: Yuelei Shen, Jian Ni, Yanan Guo, Rui Huang, Meiling Zhang, Lei Zhao, Yang Bai
  • ANTI-PD-1 ANTIBODIES AND USES THEREOF
    Publication number: 20210403570
    Abstract: This disclosure relates to anti-PD-1 (Programmed Cell Death Protein 1) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: September 17, 2021
    Publication date: December 30, 2021
    Inventors: Yi Yang, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Xiaodong Cheng, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen
  • ANTI-CD40 ANTIBODIES AND USES THEREOF
    Publication number: 20210403588
    Abstract: This disclosure relates to anti-CD40 (TNF Receptor Superfamily Member 5) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: September 8, 2021
    Publication date: December 30, 2021
    Inventors: Yi Yang, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen, Jingshu Xie
  • Anti-PD-1 antibodies and uses thereof
    Patent number: 11155625
    Abstract: This disclosure relates to anti-PD-1 (Programmed Cell Death Protein 1) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: October 26, 2021
    Assignee: Eucure (Beijing) Biopharma Co., Ltd
    Inventors: Yi Yang, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Xiaodong Cheng, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen
  • Anti-CD40 antibodies and uses thereof
    Patent number: 11142582
    Abstract: This disclosure relates to anti-CD40 (TNF Receptor Superfamily Member 5) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: October 12, 2021
    Assignee: Eucure (Beijing) Biopharma Co., Ltd
    Inventors: Yi Yang, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen, Jingshu Xie
  • ANTI-PD-1 ANTIBODIES AND USES THEREOF
    Publication number: 20210284735
    Abstract: This disclosure relates to anti-PD-1 (Programmed Cell Death Protein 1) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: May 19, 2021
    Publication date: September 16, 2021
    Inventors: Yi Yang, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen, Jingshu Xie
  • ANTI-CD3e ANTIBODIES AND USES THEREOF
    Publication number: 20210269525
    Abstract: This disclosure relates to anti-CD3e (T-cell surface glycoprotein CD3 epsilon chain) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: June 19, 2019
    Publication date: September 2, 2021
    Inventors: Yi Yang, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Xiaodong Cheng, Yuelei Shen, Jian Ni, Yanan Guo
  • Real-time speech analysis method and system using speech recognition and comparison with standard pronunciation
    Patent number: 11062726
    Abstract: A method of providing real-time speech analysis to a user includes capturing a speech input, performing a real-time recognition of the speech input including converting the speech input to a text, analyzing the recognized speech input to identify an error in a voice of the user, the analyzing including comparing a voice of a correct text generated by an automated speech generation system with the captured speed input, and processing the text to extract a context dialog prompt.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: July 13, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Sasha P. Caskey, Jian Ni, Andrzej Sakrajda, Hui Wan, Cheng Wu
  • ANTI-OX40 ANTIBODIES AND USES THEREOF
    Publication number: 20210206866
    Abstract: This disclosure relates to anti-OX40 (TNF Receptor Superfamily Member 4, or TNFRSF4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: January 5, 2021
    Publication date: July 8, 2021
    Inventors: Yi Yang, Yanan Guo, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Xiaodong Cheng, Yuelei Shen, Jian Ni
  • ANTI-TNFRSF9 ANTIBODIES AND USES THEREOF
    Publication number: 20210206867
    Abstract: This disclosure relates to anti-TNFRSF9 (tumor necrosis factor receptor superfamily member 9) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: March 12, 2021
    Publication date: July 8, 2021
    Inventors: Yi Yang, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen
  • ANTI-CTLA4 ANTIBODIES AND USES THEREOF
    Publication number: 20210188981
    Abstract: This disclosure relates to anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA4 or CTLA-4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: February 22, 2021
    Publication date: June 24, 2021
    Inventors: Yi Yang, Yanan Guo, Xiaodong Cheng, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni
  • Anti-CTLA4 antibodies and uses thereof
    Patent number: 11034764
    Abstract: This disclosure relates to anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA4 or CTLA-4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: June 15, 2021
    Assignee: Eucure (Beijing) Biopharma Co., Ltd
    Inventors: Yi Yang, Yanan Guo, Xiaodong Cheng, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni
  • ANTI-CD40 ANTIBODIES AND USES THEREOF
    Publication number: 20210155705
    Abstract: This disclosure relates to anti-CD40 (TNF Receptor Superfamily Member 5) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: January 14, 2021
    Publication date: May 27, 2021
    Inventors: Yi Yang, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen, Jingshu Xie
  • Anti-CTLA4 antibodies and uses thereof
    Patent number: 11001632
    Abstract: This disclosure relates to anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA4 or CTLA-4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: May 11, 2021
    Assignee: Eucure (Beijing) Biopharma Co., Ltd
    Inventors: Yi Yang, Yanan Guo, Xiaodong Cheng, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD47
    Publication number: 20210120790
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD47, and methods of use thereof.
    Type: Application
    Filed: November 2, 2020
    Publication date: April 29, 2021
    Inventors: Yuelei Shen, Yang Bai, Jian Ni, Rui Huang, Chengzhang Shang, Yanan Guo
  • Water circulation system for air conditioning system and control method thereof
    Patent number: 10948211
    Abstract: A water circulation system for air conditioning system and a control method thereof, wherein the water circulation loop comprises: a main loop provided with air-conditioning indoor units, air-conditioning outdoor units and an actuator, and a bypass branch connected between upstream and downstream of the air-conditioning outdoor units and provided with a bypass valve; the control method comprises: S100, starting the water circulation system after receiving a start command; S200, executing a PID control step after initialization and a first preset time period of the water circulation system; S300, executing a feed forward control step when the operating states of the air-conditioning indoor units and/or the air-conditioning outdoor units are changed, and going back to execute the PID control step after a second preset time period; and S400, executing a shutdown step of the water circulation system after receiving a shutdown command.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: March 16, 2021
    Assignee: CARRIER CORPORATION
    Inventors: Liang Chang, Jingwei Sun, Pei Sun, Lishan Wang, Jian Ni, Qing Lu
  • Anti-OX40 antibodies and uses thereof
    Patent number: 10934365
    Abstract: This disclosure relates to anti-OX40 (TNF Receptor Superfamily Member 4, or TNFRSF4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: March 2, 2021
    Assignee: Eucure (Beijing) Biopharma Co., Ltd
    Inventors: Yi Yang, Yanan Guo, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Xiaodong Cheng, Yuelei Shen, Jian Ni
  • Genetically modified mice expressing humanized CD47
    Patent number: 10918095
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD47, and methods of use thereof.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: February 16, 2021
    Assignee: Beijing Biocytogen Co., Ltd
    Inventors: Yuelei Shen, Yang Bai, Jian Ni, Rui Huang, Chengzhang Shang, Yanan Guo
  • ANTI-OX40 ANTIBODIES AND USES THEREOF
    Publication number: 20200332018
    Abstract: This disclosure relates to anti-OX40 (TNF Receptor Superfamily Member 4, or TNFRSF4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: May 22, 2020
    Publication date: October 22, 2020
    Inventors: Yi Yang, Yanan Guo, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Xiaodong Cheng, Yuelei Shen, Jian Ni
  • ANTI-PD-1 ANTIBODIES AND USES THEREOF
    Publication number: 20200332007
    Abstract: This disclosure relates to anti-PD-1 (Programmed Cell Death Protein 1) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: July 2, 2020
    Publication date: October 22, 2020
    Inventors: Yi Yang, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Xiaodong Cheng, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen