Patents by Inventor Jian Ping Lai
Jian Ping Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230392128Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes exhibit improved alpha-glucan product yields and/or lower leucrose yields, for example. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.Type: ApplicationFiled: January 20, 2023Publication date: December 7, 2023Inventors: Yougen Li, Ellen D. Semke, Qiong Cheng, Jian Ping Lai
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Publication number: 20230138517Abstract: Provided herein, inter alia, are compositions comprising oxygen tolerant strains of Megasphaera elsdenii and methods of making and using the same to promote improvement of one or more metrics in an animal, such as increased bodyweight/carcass gain, increased feed intake, decreased feed conversion ratio (FCR), decreased medical costs, decreased transition period, decrease use of antibiotics, and reduced mortality.Type: ApplicationFiled: February 5, 2021Publication date: May 4, 2023Inventors: Marion Bernardeau, Qiong Cheng, Raymond E. Jackson, Jian Ping Lai, Yang-Xiang Li, Wenting Li, Charlotte Horsmans Poulsen, Yixin Ren, Luan Tao, Qiong Wang, Derek Joseph Zimmer, Susan Hennessey
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Patent number: 11560551Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes exhibit improved alpha-glucan product yields and/or lower leucrose yields, for example. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.Type: GrantFiled: December 11, 2020Date of Patent: January 24, 2023Assignee: NUTRITION & BIOSCIENCES USA 4, INC.Inventors: Yougen Li, Ellen D. Semke, Qiong Cheng, Jian Ping Lai
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Publication number: 20220275112Abstract: An enzymatically produced soluble ?-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble ?-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble ?-glucan fiber are also provided.Type: ApplicationFiled: February 25, 2022Publication date: September 1, 2022Inventors: Qiong Cheng, Robert DiCosimo, Arthur Ouwehand, Zheng You, Mark S. Payne, Jian Ping Lai, Kristin Ruebling-Jass, Steven Cary Rothman
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Patent number: 11261264Abstract: An enzymatically produced soluble ?-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble ?-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble ?-glucan fiber are also provided.Type: GrantFiled: June 25, 2019Date of Patent: March 1, 2022Assignee: NUTRITION & BIOSCIENCES USA 4, INC.Inventors: Qiong Cheng, Robert DiCosimo, Arthur Ouwehand, Zheng You, Mark S. Payne, Jian Ping Lai, Kristin Ruebling-Jass, Steven Cary Rothman
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Publication number: 20210254029Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes exhibit improved alpha-glucan product yields and/or lower leucrose yields, for example. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.Type: ApplicationFiled: December 11, 2020Publication date: August 19, 2021Inventors: YOUGEN LI, ELLEN D. SEMKE, QIONG CHENG, JIAN PING LAI
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Patent number: 10907185Abstract: An enzymatically produced soluble ?-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble ?-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble ?-glucan fiber are also provided.Type: GrantFiled: May 22, 2015Date of Patent: February 2, 2021Assignee: DUPONT INDUSTRIAL BIOSCIENCES USA, LLCInventors: Qiong Cheng, Robert Dicosimo, Arthur Ouwehand, Zheng You, Jian Ping Lai, Zheyong Yu, Zhenghong Zhang
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Patent number: 10865393Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes exhibit improved alpha-glucan product yields and/or lower leucrose yields, for example. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.Type: GrantFiled: September 11, 2018Date of Patent: December 15, 2020Assignee: DUPONT INDUSTRIAL BIOSCIENCES USA, LLCInventors: Yougen Li, Ellen D. Semke, Qiong Cheng, Jian Ping Lai
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Publication number: 20190389978Abstract: An enzymatically produced soluble ?-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble ?-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble ?-glucan fiber are also provided.Type: ApplicationFiled: June 25, 2019Publication date: December 26, 2019Inventors: Qiong Cheng, Robert DiCosimo, Arthur Ouwehand, Zheng You, Mark S. Payne, Jian Ping Lai, Kristin Ruebling-Jass, Steven Cary Rothman
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Patent number: 10351633Abstract: An enzymatically produced soluble ?-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble ?-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble ?-glucan fiber are also provided.Type: GrantFiled: May 22, 2015Date of Patent: July 16, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Qiong Cheng, Robert Dicosimo, Arthur Ouwehand, Zheng You, Mark S. Payne, Jian Ping Lai, Kristin Ruebling-Jass, Steven Cary Rothman
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Publication number: 20190078063Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes exhibit improved alpha-glucan product yields and/or lower leucrose yields, for example. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.Type: ApplicationFiled: September 11, 2018Publication date: March 14, 2019Inventors: YOUGEN LI, Ellen D. Semke, Qiong Cheng, Jian Ping Lai
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Publication number: 20170218093Abstract: An enzymatically produced soluble ?-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble ?-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble ?-glucan fiber are also provided.Type: ApplicationFiled: May 22, 2015Publication date: August 3, 2017Inventors: Qiong Cheng, Robert Dicosimo, Arthur Ouwehand, Zheng You, Mark S. Payne, Jian Ping Lai, Kristin Ruebling-Jass, Steven Cary Rothman
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Publication number: 20170198324Abstract: An enzymatically produced soluble ?-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble ?-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble ?-glucan fiber are also provided.Type: ApplicationFiled: May 22, 2015Publication date: July 13, 2017Inventors: Qiong Cheng, Robert Dicosimo, Arthur Ouwehand, Zheng You, Jian Ping Lai, Zheyong YU, Zhenghong ZHANG
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Publication number: 20140093927Abstract: Variant sucrose transporter polypeptides that enable faster sucrose utilization in bacteria are described. Additionally, variant or recombinant bacteria comprising these variant sucrose transporter polypeptides, and methods of utilizing the bacteria to produce products such as glycerol and glycerol-derived products are provided.Type: ApplicationFiled: December 5, 2013Publication date: April 3, 2014Applicant: E. I. du Pont de Nemours and CompanyInventors: Qi CHEN, Qiong CHENG, Jian Ping LAI, Kristin RUEBLING-JASS
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Patent number: 8673602Abstract: Recombinant bacteria having an improved ability to utilize sucrose are provided. These recombinant bacteria have nucleotide sequences encoding sucrose utilization polypeptides integrated into their genome between the yihP gene or its homolog and the yihO gene or its homolog. Additionally, methods of utilizing the recombinant bacteria to produce products such as glycerol and glycerol-derived products are provided.Type: GrantFiled: August 16, 2011Date of Patent: March 18, 2014Assignee: E I du Pont de Nemours and CompanyInventors: Qi Chen, Qiong Cheng, Jian Ping Lai, Kristin Ruebling-Jass
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Patent number: 8629243Abstract: Variant sucrose transporter polypeptides that enable faster sucrose utilization in bacteria are described. Additionally, variant or recombinant bacteria comprising these variant sucrose transporter polypeptides, and methods of utilizing the bacteria to produce products such as glycerol and glycerol-derived products are provided.Type: GrantFiled: August 16, 2011Date of Patent: January 14, 2014Assignee: E I du Pont de Nemours and CompanyInventors: Qi Chen, Qiong Cheng, Jian Ping Lai, Kristin Ruebling-Jass
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Publication number: 20130045519Abstract: Recombinant bacteria having an improved ability to utilize sucrose are provided. These recombinant bacteria have nucleotide sequences encoding sucrose utilization polypeptides integrated into their genome between the yihP gene or its homolog and the yihO gene or its homolog. Additionally, methods of utilizing the recombinant bacteria to produce products such as glycerol and glycerol-derived products are provided.Type: ApplicationFiled: August 16, 2011Publication date: February 21, 2013Applicant: E. I. DU PONT DE NEMOURS AND COMPANYInventors: Qi Chen, Qiong Cheng, Jian Ping Lai, Kristin Ruebling-Jass
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Publication number: 20130045518Abstract: Variant sucrose transporter polypeptides that enable faster sucrose utilization in bacteria are described. Additionally, variant or recombinant bacteria comprising these variant sucrose transporter polypeptides, and methods of utilizing the bacteria to produce products such as glycerol and glycerol-derived products are provided.Type: ApplicationFiled: August 16, 2011Publication date: February 21, 2013Applicant: E. I. DU PONT DE NEMOURS AND COMPANYInventors: QI Chen, Qiong Cheng, Jian Ping Lai, Kristin Ruebling-Jass
