Abstract: The invention provides isoform-selective anti-TGF? antibodies and methods of using the same. In particular, isoform-selective anti-TGF?2, anti-TGF?3, and anti-TGF?2/3 monoclonal antibodies are provided, e.g., for the treatment of fibrosis and other TGF?-related disorders.

Abstract: Methods and compositions for treating a disorder of cardiac muscle and/or skeletal muscle in a subject according to aspects of the present disclosure. Treatment methods include administering a therapeutically effective dose of a C-terminal portion of troponin I capable of reducing sensitivity of cardiac muscle and/or skeletal muscle to Ca2+ without decreasing maximum force production. Assays for identification of compounds capable of reducing sensitivity of cardiac muscle and/or skeletal muscle to Ca2+ without decreasing maximum force production are further provided.

Abstract: Disclosed is a gel material having a high water content and excellent mechanical properties. The gel material includes repeating units derived from the following monomers (A) and (B): (A) an anionic monomer containing a polymerizable carbon-carbon multiple bond and an aromatic ring, and (B) a cationic monomer containing a polymerizable carbon-carbon multiple bond and an aromatic ring. The gel material has a water content of 20% by mass to 95% by mass, a tensile elastic modulus of 9 MPa to 1000 MPa, and a tensile elongation at break of 50% to 5000%.

Abstract: The disclosure describes a method that includes forming a soft magnetic material by a technique including melt spinning. The soft magnetic material includes at least one of: at least one of an ??-Fe16(NxZ1-x)2 phase domain or an ??-Fe8(NxZ1-x), where Z includes at least one of C, B, or O, and where x is a number greater than zero and less than one; or at least one of an ??-Fe16N2 phase domain or an ??-Fe8N phase domain, and at least one of an ??-Fe16Z2 phase domain or an ??-Fe8Z phase domain.

Abstract: In general, the disclosure is directed to bulk iron-nitride materials having a polycrystalline microstructure having pores including a plurality of crystallographic grains surrounded by grain boundaries, where at least one crystallographic grain includes an iron-nitride phase including any of a body centered cubic (bcc) structure, a body centered tetragonal (bct), and a martensite structure. The disclosure further describes techniques producing a bulk iron-nitride material having a polycrystalline microstructure, including: melting an iron source to obtain a molten iron source; fast belt casting the molten iron source to obtain a cast iron source; cooling and shaping the cast iron source to obtain a bulk iron-containing material having a body-centered cubic (bcc) structure; annealing the bulk iron-containing material at an austenite transformation temperature and subsequently cooling the bulk iron-containing material; and nitriding the bulk iron-containing material to obtain the bulk iron-nitride material.

Abstract: Techniques are disclosed concerning applied magnetic field synthesis and processing of iron nitride magnetic materials. Some methods concern casting a material including iron in the presence of an applied magnetic field to form a workpiece including at least one iron-based phase domain including uniaxial magnetic anisotropy, wherein the applied magnetic field has a strength of at least about 0.01 Tesla (T). Also disclosed are workpieces made by such methods, apparatus for making such workpieces and bulk materials made by such methods.

Abstract: A device which includes a free layer and a current channel. The free layer has a configurable magnetization state. The current channel includes a low-symmetry crystal with only one mirror plane. The low-symmetry material has relatively large unconventional spin Hall effect (SHE). A current through the current channel applies a spin-orbit torque that sets the magnetization state of the free layer.

Abstract: A method of making a catalyst layer of a membrane electrode assembly (MEA) for a polymer electrolyte membrane fuel cell includes the step of preparing a porous buckypaper layer comprising at least one selected from the group consisting of carbon nanofibers and carbon nanotubes. Platinum group metal nanoparticles are deposited in a liquid solution on an outer surface of the buckypaper to create a platinum group metal nanoparticle buckypaper. A proton conducting electrolyte is deposited on the platinum group metal nanoparticles by electrophoretic deposition to create a proton-conducting layer on the an outer surface of the platinum nanoparticles. An additional proton-conducting layer is deposited by contacting the platinum group metal nanoparticle buckypaper with a liquid proton-conducting composition in a solvent. The platinum group metal nanoparticle buckypaper is dried to remove the solvent. A membrane electrode assembly for a polymer electrolyte membrane fuel cell is also disclosed.

Abstract: A structured material assembly for removing CO2 from a gas, comprises a substrate, a sorbent for adsorbing CO2 from the gas, and a desorption material integrated into the structured material assembly, which is responsive to inputted energy to generate heat to desorb CO2 from the sorbent. The CO2-containing gas may comprise ambient air.

Abstract: Provided is a resin film that has a stress integral value of greater than 10 MPa and 1000 MPa or less when uniaxially stretched at a tensile speed of 300 mm/min at 25° C. until it breaks. The resin film showing these properties is supple and durable.

Abstract: The disclosure is directed to an iron-nitride material having a polycrystalline microstructure including a plurality of elongated crystallographic grains with grain boundaries, the iron-nitride material including at least one of an ??-Fe16N2 phase and a body-center-tetragonal (bct) phase comprising Fe and N. The disclosure is also directed a method producing an iron-nitride material.

Abstract: Processes are described for removal of CO2 from a CO2-containing gas comprising water vapor, including: (a) contacting the CO2-containing gas comprising water vapor with an alkali metal carbonate adsorbent under conditions causing (i) the water vapor in the CO2-containing gas comprising water vapor to react with the alkali metal carbonate to form a corresponding alkali metal carbonate hydrate, and (ii) the corresponding alkali metal carbonate hydrate to react with CO2 in the CO2-containing gas comprising water vapor to form a corresponding alkali metal sesquicarbonate; and (b) reacting the alkali metal sesquicarbonate under conditions effective to recover CO2 and to regenerate alkali metal carbonate hydrate adsorbent therefrom. Systems for carrying out such process are also described, which are applicable to direct air capture (DAC) of CO2, as well as to treatment of CO2-containing flue gases from power plants and other oxidation and combustion sources.

Abstract: All example composition may include a plurality of grains including an iron nitride phase. The plurality of grains may have an average wain size between about 10 nm and about 200 nm. An example technique may include treating a composition including a plurality of grains including au iron-based phase to adjust an average grain size of the plurality of grains to between about 20 nm and about 100 ma. The example technique may include nitriding the plurality of grains to form or grow an iron nitride phase.

Abstract: The invention provides isoform-selective anti-TGF? antibodies and methods of using the same. In particular, isoform-selective anti-TGF?2, anti-TGF?3, and anti-TGF?2/3 monoclonal antibodies are provided, e.g., for the treatment of fibrosis and other TGF?-related disorders.

Abstract: The present invention relates to microfluidic or millifluidic chips (1) comprising at least one pressure sensing unit (4) able to measure a fluid flow pressure. The present invention also relates to a method for a direct and contact-free measuring of a local pressure of a fluid circulating in a microfluidic circuit, using a microfluidic or millifluidic chips (1) according to the invention.

Abstract: A circuit includes a first two-state device, a second two-state device and a third two-state device, each two-state device having a first resistance in a first state and a second resistance in a second state. First control elements are configured to apply a first voltage to the first two-state device to stochastically place the first two-state device in either the first state or the second state. Second control elements are configured to apply a second voltage to the second two-state device to stochastically place the second two-state device in either the first state or the second state. Third control elements are configured to send respective currents through the first two-state device and the second two-state device so as to place the third two-state device in either the first state or the second state based on the state of the first two-state device and the state of the second two-state devices.

Abstract: Example nanoparticles may include an iron-based core, and a shell. The shell may include a non-magnetic, anti-ferromagnetic, or ferrimagnetic material. Example alloy compositions may include an iron-based grain, and a grain boundary. The grain boundary may include a non-magnetic, anti-ferromagnetic, or ferrimagnetic material. Example techniques for forming iron-based core-shell nanoparticles may include depositing a shell on an iron-based core. The depositing may include immersing the iron-based core in a salt composition for a predetermined period of time. The depositing may include milling the iron-based core with a salt composition for a predetermined period of time. Example techniques for treating a composition comprising core-shell nanoparticles may include nitriding the composition.

Abstract: An instrument holder and a method for aligning an instrument for accessing a target within a subject, comprising a first layer, a second layer, an instrument guide with an entry and an exit point, connecting between the two layers and configured to guide the instrument from the entry point to the exit point, wherein the instrument holder is transparent to an imaging system except that the first layer and second layer include markings that are visible by the imaging system.

Abstract: A hybrid lithium-ion battery-capacitor (H-LIBC) energy storage device includes a hybrid composite cathode electrode having a lithium ion battery (LIB) cathode active material and a lithium ion capacitor (LIC) cathode active material. An anode electrode having a surface is pre-loaded and pressed with a lithium (Li) thin film source. The anode electrode is pre-lithiated with the lithium film source by positioning the Li film source on the surface of anode electrode after electrolyte filling and soaking processes, a separator and an organic solvent electrolytic solution including a lithium salt electrolyte are also provided. A method of making a hybrid lithium-ion battery-capacitor and a method of making a hybrid composite cathode for a hybrid lithium-ion battery-capacitor are also disclosed.

Abstract: Embodiments of the disclosure provide an information display method and apparatus, an electronic device, and a computer storage medium. The method includes: obtaining a motion status of a target object at a current moment in a virtual scene and a first operation for controlling the target object to move in the virtual scene; predicting a first moving track along which the target object is to move within a period of time after the current moment based on the motion status of the target object at the current moment and the first operation; and displaying the first moving track and a second moving track, the second moving track being a moving track along which the target object has moved before the current moment.