Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: Disclosed are an electric wheel assembly applicable for a parallelly mounted dual-tire wheel, an axle, and a vehicle. The electric wheel assembly includes a wheel and support axle assembly, an internal-rotor hub motor, a planetary gear reducer and a brake system. A planetary carrier is connected to a hub. The hub is connected to a spoke and a rim. The wheel support axle passes through a rotor sleeve and is provided with a hub bearing to support the hub and a whole wheel. A sun gear disposed at an end of the rotor sleeve of the internal-rotor hub motor is a power input of the planetary gear speed reducer, and the planetary carrier is a power output. A planetary gear of the planetary gear reducer is a tower-shaped gear and realizes a relatively high transmission ratio under a condition that an axial length is relatively small.

Abstract: A method for diagnosing degradation of a fuel cell stack, including: S10, qualitatively determining a degradation type of the fuel cell stack according to a voltage-current curve of the fuel cell stack; S20, quantitatively measuring parameter values of each of individual cells of the fuel cell stack according to the degradation type, and quantitatively determining a degradation degree of each of the individual cells according to the parameter values; S30, determining a uniformity degradation degree among the individual cells of the fuel cell stack according to a non-uniformity degree of a voltage distribution of the individual cells. By qualitatively determining the degradation type of the fuel cell stack, the degradation condition of the entire fuel cell stack may be obtained.

Abstract: A low-floor electric axle assembly including: an axle housing, two hub motors, two planetary gear reducers, two hubs, a brake system, two C-shaped beams, and a suspension system. Mechanical mounting of the suspension system is compatible with a conventional axle. The axle housing has a left and right symmetrical dumbbell-shaped structure configured to bear a weight of a vehicle. The hub motors are inner rotor type motors and are separately arranged at two ends of the axle housing left and right symmetrically. The hub motors are arranged coaxially with two wheels respectively. Two hub motor rotors are connected to the planetary gear reducers respectively. Each of the planetary gear reducers is a single-stage planetary gear reducer. A sun gear of each of the planetary gear reducers receives power outputted by each of the hub motor. Two planetary gear reducer housings are power output ends connected to two rims respectively.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: Provided is a method for preparing a crosslinked polyvinyl chloride structure foamed material by using a physical foaming agent, comprising: melting and mixing a polyvinyl chloride resin, a modified resin, an isocyanate, an anhydride, a nucleating agent and a heat stabilizer to obtain a blank; immersing the blank into a foaming gas for foaming to obtain a foamed body; and subjecting the foamed body to crosslinking curing to obtain a crosslinked polyvinyl chloride structure foamed material. According to the present invention, the crosslinked polyvinyl chloride structure foamed material is prepared by means of a brand-new process route, and the composition and proportion of the PVC resin and other raw materials can be adjusted in a wide range; and carbon dioxide or nitrogen is used for foaming. Further provided is a crosslinked polyvinyl chloride structure foamed material.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: A network call method, a server, a call terminal, a network call system, and a storage medium are provided. The network call method includes: receiving a reservation request transmitted by a call reservation terminal, the reservation request including a first communication identifier of a first call terminal; generating a chat room identifier of a chat room in a social network application; generating a call reservation notification, the call reservation notification including an access link generated according to the chat room identifier; and transmitting the call reservation notification to a communication client of the first call terminal according to the first communication identifier of the first call terminal.

Abstract: Provided are certain cellulose ester compositions which serve as improved anti-tack additives for various thermoplastic polymers, in applications such as woven and non-woven fibers, laminates including the composition, fabrics including the composition, apparel and garments, textiles including the composition, etc.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: Embodiments of the present disclosure provide a method and apparatus for displaying measurement parameters. The method comprises: in response to receiving an input signal indicating to display one or more measurement parameters of an electrical device, reading from a memory a first data associated with the one or more measurement parameters for display, and generating an update request for the first data; sending the update request to the electrical device; and in response to receiving, from the electrical device, a second data associated with the one or more measurement parameters, writing the second data to the memory as updated data to replace the first data. According to embodiments of the present disclosure, a large amount of measurement data of a power distribution system can be collected and displayed, data display is decoupled from data communication, and the impact of communication delay is eliminated, thereby improving the user's experience.

Abstract: A multi-environment integrative thermal management method for a fuel cell vehicle is provided. The method can ensure the accuracy and the stability of the control for a temperature of a fuel cell system of the fuel cell vehicle in a complicated and changeable environment, decrease the energy consumption of the entire vehicle, and increase the economical efficiency of the entire vehicle.

Abstract: The present disclosure relates to, among other things, antibody-drug conjugates comprising a STING agonist cyclic di-nucleotide conjugated to an antibody, preparation methods therefor, and uses therefor.

Abstract: A multi-environment integrative thermal management method for a fuel cell vehicle is provided. The method can ensure the accuracy and the stability of the control for a temperature of a fuel cell system of the fuel cell vehicle in a complicated and changeable environment, decrease the energy consumption of the entire vehicle, and increase the economical efficiency of the entire vehicle.