Patents by Inventor Jian Qiu

Jian Qiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Substituted Bicyclic Aromatic Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20150183774
    Abstract: The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: March 3, 2015
    Publication date: July 2, 2015
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Dihydropyrimidin-2(1H)-one compounds as S-nitrosoglutathione reductase inhibitors
    Patent number: 9067893
    Abstract: The present invention is directed to novel dihydropyrimidin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: June 30, 2015
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu
  • Novel Dihydropyridin-2(1H)-One Compounds as S-Nitrosoglutathione Reductase Inhibitors and Neurokinin-3 Receptor Antagonists
    Publication number: 20150157616
    Abstract: The present invention is directed to novel dihydropyridin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors and/or Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: January 15, 2015
    Publication date: June 11, 2015
    Inventors: Xicheng Sun, Jian Qiu
  • Pyrrole inhibitors of S-nitrosoglutathione reductase
    Patent number: 9029402
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: January 2, 2014
    Date of Patent: May 12, 2015
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents
    Publication number: 20150126570
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Application
    Filed: January 15, 2015
    Publication date: May 7, 2015
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Substituted bicyclic aromatic compounds as S-nitrosoglutathione reductase inhibitors
    Patent number: 9012646
    Abstract: The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: April 21, 2015
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Novel Substituted Quinoline Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20150080429
    Abstract: The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: November 13, 2014
    Publication date: March 19, 2015
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
    Patent number: 8957105
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: February 17, 2015
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Dihydropyridin-2(1H)-one compound as S-nirtosoglutathione reductase inhibitors and neurokinin-3 receptor antagonists
    Patent number: 8946434
    Abstract: The present invention is directed to novel dihydropyridin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors and/or Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: February 3, 2015
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Xicheng Sun, Jian Qiu
  • Substituted quinoline compounds as S-nitrosoglutathione reductase inhibitors
    Patent number: 8921562
    Abstract: The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: December 30, 2014
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Dihydropyrimidin-2(1H)-one compounds as neurokinin-3 receptor antagonists
    Patent number: 8906933
    Abstract: The present invention is directed to novel dihydropyrimidin-2(1H)-one compounds useful as Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: December 9, 2014
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Xicheng Sun, Jian Qiu
  • Novel Substituted Bicyclic Aromatic Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20140329821
    Abstract: The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: July 9, 2014
    Publication date: November 6, 2014
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
    Patent number: 8846736
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: September 30, 2014
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Novel S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20140275185
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Application
    Filed: May 30, 2014
    Publication date: September 18, 2014
    Applicant: N30 PHARMACEUTICALS, INC.
    Inventors: Xicheng Sun, Jian Qiu
  • Novel Dihydropyrimidin-2(1H)-one Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20140235640
    Abstract: The present invention is directed to novel dihydropyrimidin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: April 28, 2014
    Publication date: August 21, 2014
    Applicant: N30 PHARMACEUTICALS, INC.
    Inventors: Xicheng Sun, Jian Qiu
  • Substituted bicyclic aromatic compounds as S-nitrosoglutathione reductase inhibitors
    Patent number: 8785643
    Abstract: The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: July 22, 2014
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents
    Publication number: 20140194481
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Application
    Filed: March 11, 2014
    Publication date: July 10, 2014
    Applicant: N30 Pharmaceuticals, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents
    Publication number: 20140194425
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Application
    Filed: March 11, 2014
    Publication date: July 10, 2014
    Applicant: N30 Pharmaceuticals, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • DELTA-SIGMA MODULATION APPARATUS AND DYNAMIC ELEMENT-MATCHING CIRCUIT THEREOF
    Publication number: 20140184433
    Abstract: A delta-sigma modulation apparatus and a dynamic element-matching circuit thereof are disclosed. The dynamic element-matching circuit includes a data aligner, a logic operation circuit, and a delayer. The data aligner receives an input matching data and a pointer signal and shifts the input matching data according to the pointer signal to generate an output matching data. The logic operation circuit receives the output matching data and performs a logic operation on the output matching data to generate a preceding pointer signal. The delayer receives the preceding pointer signal and delays the preceding pointer signal according to a sample clock pulse to generate the pointer signal.
    Type: Application
    Filed: March 12, 2013
    Publication date: July 3, 2014
    Applicants: QUADLINK TECHNOLOGY, INC., QUADLINK TECHNOLOGY, INC.
    Inventor: Jian-Qiu Chen
  • S-nitrosoglutathione reductase inhibitors
    Patent number: 8759548
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: June 24, 2014
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Xicheng Sun, Jian Qiu