Abstract: A floor mat with a damp-proof effect includes a base and a mat portion. The base has a bottom plate, a blocking member, a female fastener, and a male fastener. The bottom plate has a top side and a bottom side. Plural supporting legs extend downward from the bottom side. The blocking member runs along the periphery of the bottom plate and extends upward of, and forms a receiving groove together with, the top side. The female fastener is provided on the periphery of the bottom plate and forms an opening. The male fastener is provided on the same periphery and extends downward of the bottom side. The height of the mat portion, which is detachably received in the receiving groove, is flush with or higher than the top edge of the blocking member. The floor mat will not easily get damp.