Abstract: Disclosed are compounds of Formula I, or a salt thereof: where A, B, D, X, R1, R2 and R8 are as defined herein, which compounds have properties for antagonizing PCSK9. Also described are pharmaceutical formulations comprising the compounds of Formula I or their salts, and methods of treating cardiovascular disease and conditions related to PCSK9 activity, e.g. atherosclerosis, hypercholesterolemia, coronary heart disease, metabolic syndrome, acute coronary syndrome, or related cardiovascular disease and cardiometabolic conditions.

Abstract: An adjustable seat includes a seat frame and an adjustable assembly. The seat frame includes a first seat body and a second seat body spaced apart each other to define an adjustment channel between the first and second seat bodies. The adjustable assembly, which supported underneath the seat frame and configured to selectively adjust a distance between the first and second seat bodies, includes an adjustor and first and second adjustable members coupled at the first and second seat bodies respectively and aligned with each other. The adjustor is linked with the first and second adjustable members and configured to be driven to rotate at a rotatable direction along a centerline of the adjustment channel to selectively adjust a width of the adjustment channel so as to selectively adjust the distance between the first and second seat bodies.

Abstract: An electrical responsive graphene-PVDF material and the manufacturing method thereof is disclosed in the present invention. The method includes three steps. Firstly, prepare a mother solution of PVDF. Then, add graphene powders into the mother solution of PVDF to prepare a graphene-PVDF slurry. At last, remove the solvent from the graphene-PVDF slurry to directly form an electrical responsive graphene-PVDF material. Due to the ability of transforming the non-electrical energy into the electrical energy, the electrical responsive graphene-PVDF material can be formed for many different applications in the form of individual film or of film with a substrate via various film formation methods.

Abstract: A robotic cleaner may include one or more driven wheels, at least one environmental sensor, and a mop module. The mop module may include a tank having a tank inlet and a tank outlet, a pad coupled at a bottom side of the tank, the pad configured to contact a surface to be cleaned and to receive liquid from the tank outlet, and a latch configured to transition between a latched position, a release position, and a refill position. When in the latched position and in the release position, at least a portion of the latch may extend over the tank inlet and, when in the refill position, the latch may be displaced from the tank inlet, exposing the tank inlet.

Abstract: A connection manner identification method includes power sourcing equipment separately sending load adjustment indications to powered devices by using data ports, where each load adjustment indication in the load adjustment indications indicates a corresponding powered device to adjust a load. The powered devices are separately connected to power supply ports of the power sourcing equipment by using power supply cables, and the powered devices are separately connected to the data ports of the power sourcing equipment by using data cables. The power sourcing equipment obtains output power changes of the power supply ports caused by load adjustment of the powered devices, and the power sourcing equipment determines, based on the output power changes, a first data port and a power supply port that are connected to a same powered device in the powered devices.

Abstract: The present disclosure generally relates to magnetic recording devices with stable magnetization. The magnetic recording device comprises a lower leading shield, an upper leading shield disposed on the lower leading shield, a main pole disposed above the upper leading shield, a trailing shield disposed above the main pole and upper leading shield, and an upper return pole disposed above the trailing shield. A first non-magnetic layer is disposed between the lower leading shield and the upper leading shield, and a second non-magnetic layer is disposed between the trailing shield and the upper return pole. The lower leading shield has a different domain state than the upper leading shield, and the trailing shield and the upper leading shield have a same domain state. The materials and thickness of the first and second non-magnetic layers result in magnetostatic coupling or anti-ferromagnetic coupling.

Abstract: An electrical responsive graphene-PVDF material and the manufacturing method thereof is disclosed in the present invention. The method includes three steps. Firstly, prepare a mother solution of PVDF. Then, add graphene powders into the mother solution of PVDF to prepare a graphene-PVDF slurry. At last, remove the solvent from the graphene-PVDF slurry to directly form an electrical responsive graphene-PVDF material. Due to the ability of transforming the non-electrical energy into the electrical energy, the electrical responsive graphene-PVDF material can be formed for many different applications in the form of individual film or of film with a substrate via various film formation methods.

Abstract: The present disclosure generally relates to magnetic recording devices with stable magnetization. The magnetic recording device comprises a lower leading shield, an upper leading shield disposed on the lower leading shield, a main pole disposed above the upper leading shield, a trailing shield disposed above the main pole and upper leading shield, and an upper return pole disposed above the trailing shield. A first non-magnetic layer is disposed between the lower leading shield and the upper leading shield, and a second non-magnetic layer is disposed between the trailing shield and the upper return pole. The lower leading shield has a different domain state than the upper leading shield, and the trailing shield and the upper leading shield have a same domain state. The materials and thickness of the first and second non-magnetic layers result in magnetostatic coupling or anti-ferromagnetic coupling.

Abstract: A communication system includes a first device and a second device connected through an electro-optical composite cable. The electro-optical composite cable includes an optical fiber and a power supply cable. The optical fiber is used to transmit a data signal. The power supply cable is used to transmit a direct current. The first device is configured to send a first alternating-current signal to the second device through the power supply cable. The second device is configured to switch a running status based on the first alternating-current signal.

Abstract: A power supply detection apparatus includes a power sourcing equipment (PSE) circuit, a power supply module, and a reverse circuit. The PSE circuit is configured to send a first sounding electrical signal and a second sounding electrical signal to the reverse circuit. The reverse circuit outputs the first sounding electrical signal to a wire-pair group of an Ethernet cable, performs reverse processing on the second sounding electrical signal, and outputs a reverse-processed second sounding electrical signal to the wire-pair group. The PSE circuit is configured to determine, using the first sounding electrical signal, a forward sounding result of a to-be-detected device; and determine a reverse sounding result of the to-be-detected device based on the second sounding electrical signal. The power supply detection apparatus is configured to determine that the to-be-detected device is a non-PD when the forward sounding result or the reverse sounding result is a short circuit.

Abstract: An adjustable seat includes a seat frame and an adjustable assembly. The seat frame includes a first seat body and a second seat body spaced apart each other to define an adjustment channel between the first and second seat bodies. The adjustable assembly, which supported underneath the seat frame and configured to selectively adjust a distance between the first and second seat bodies, includes an adjustor and first and second adjustable members coupled at the first and second seat bodies respectively and aligned with each other.

Abstract: An electrical responsive graphene-PVDF material and the manufacturing method thereof is disclosed in the present invention. The method includes three steps. Firstly, prepare a mother solution of PVDF. Then, add graphene powders into the mother solution of PVDF to prepare a graphene-PVDF slurry. At last, remove the solvent from the graphene-PVDF slurry to directly form an electrical responsive graphene-PVDF material. Due to the ability of transforming the non-electrical energy into the electrical energy, the electrical responsive graphene-PVDF material can be formed for many different applications in the form of individual film or of film with a substrate via various film formation methods.

Abstract: The present invention relates to smoking articles, for example electronic cigarettes (herein referred to as “e-cigarettes”), and fluid reservoirs for use therewith or therein.

Abstract: An adjustable seat includes a seat frame and an adjustable assembly. The seat frame includes a first seat body and a second seat body spaced apart each other to define an adjustment channel between the first and second seat bodies. The adjustable assembly is supported underneath the seat frame for selectively adjusting a distance between the first and second seat bodies, wherein the adjustable assembly includes two adjustable members coupled at the first and second seat bodies respectively, and an adjustor rotatably coupled between the adjustable shafts. The adjustor is driven to rotate at a rotatable direction along a centerline of the adjustment channel to selectively adjust a width of the adjustment channel so as to selectively adjust the distance between the first and second seat bodies.

Abstract: A connection manner identification method includes power sourcing equipment separately sending load adjustment indications to powered devices by using data ports, where each load adjustment indication in the load adjustment indications indicates a corresponding powered device to adjust a load. The powered devices are separately connected to power supply ports of the power sourcing equipment by using power supply cables, and the powered devices are separately connected to the data ports of the power sourcing equipment by using data cables. The power sourcing equipment obtains output power changes of the power supply ports caused by load adjustment of the powered devices, and the power sourcing equipment determines, based on the output power changes, a first data port and a power supply port that are connected to a same powered device in the powered devices.

Abstract: The present invention relates to smoking articles, for example electronic cigarettes (h referred to as “e-cigarettes”), and fluid reservoirs for use therewith or therein.

Abstract: A light emitting device including a light emitting unit, two electrodes, a reflective member, and a light transmissive member is provided. The two electrodes are disposed on one side of the light emitting unit, and electrically connected to the light emitting unit. The reflective member is disposed on the other side of the light emitting unit, and has at least one reflective surface. The light transmissive member is disposed between the reflective member and the light emitting unit, and covers a part of the light emitting unit. A lateral surface of the light transmissive member is served as a light emitting surface of the light emitting device. A manufacturing method of a light emitting device is also provided.

Abstract: A method and system of providing decision support to first responders. One method includes identifying, with an electronic processor, a first plurality of characteristics of a first responder. The method further includes generating, with the electronic processor, a first score for the first responder based on the first plurality of characteristics. The method further includes identifying with the electronic processor, a suspect at an incident area. The method further includes identifying, with the electronic processor, a second plurality of characteristics of the suspect. The method further includes generating, with the electronic processor, a second score for the suspect based on the second plurality of characteristics. The method further includes comparing, with the electronic processor, the first score and the second score. The method further includes outputting, with an output device electrically connected to the electronic processor, a recommended action.

Abstract: A method and system of providing decision support to first responders. One method includes identifying, with an electronic processor, a first plurality of characteristics of a first responder. The method further includes generating, with the electronic processor, a first score for the first responder based on the first plurality of characteristics. The method further includes identifying with the electronic processor, a suspect at an incident area. The method further includes identifying, with the electronic processor, a second plurality of characteristics of the suspect. The method further includes generating, with the electronic processor, a second score for the suspect based on the second plurality of characteristics. The method further includes comparing, with the electronic processor, the first score and the second score. The method further includes outputting, with an output device electrically connected to the electronic processor, a recommended action.