Abstract: Detecting fine-grained similarity in image includes determining a core area of a search image by generating an image salient map from a plurality of layers of the search image and determining a connected area based on the image salient map. Feature descriptors are generated from the core area of the search image. A plurality of capsule vectors are generated from different ones of a plurality of keypoints of the feature descriptors. Capsule vectors of the search image are compared with capsule vectors of each image of the dataset to generate a top-K matrix. Similarity scores for the top-K matrix are calculated. One or more image of the dataset having fine-grained similarity with the search image are selected based a bundled similarity score for each image of the dataset. The bundled similarity score is a summation of the similarity scores of the image.

Abstract: One or more systems, devices, computer program products and/or computer-implemented methods of use provided herein relate to detecting a closed ring in a three-dimensional (3D) point cloud via cycle basis. A system can comprise a memory configured to store computer executable components; and a processor configured to execute the computer executable components stored in the memory, wherein the computer executable components can comprise a filtering component that can filter a first undirected graph of a three-dimensional (3D) point cloud, by eliminating one or more edges of the first undirected graph that are longer than an adaptive threshold, wherein filtering the first undirected graph can produce a second undirected graph; and a detection component that can detect a minimum cycle basis of the second undirected graph to determine a cycle path that can traverse an irregular annular shape that is represented by the 3D point cloud.

Abstract: A distributed data security event detection and response (DDSEDR) system includes a data security management (DSM) system and a client-side data security event confirmation and response (CDSECR) system that manage data security events, such as ransomware attacks. In at least one embodiment, the DDSEDR system provides data security event detection, confirmation, mitigation, alerting, and recovery from malicious processes and other data security events. In at least one embodiment, the DSM system monitors one or more client file event records for information that indicates a potential data security event. If the DSM system detects a potential data security threat, the DSM, sends information to the CDSECR system that causes CDSECR system to inspect one or more files associated with the potential data security event to determine whether an actual data security event occurred and initiate a responsive action when the CDSECR system detects an actual data security event.

Abstract: Provided is a method for preparing a crosslinked polyvinyl chloride structure foamed material by using a physical foaming agent, comprising: melting and mixing a polyvinyl chloride resin, a modified resin, an isocyanate, an anhydride, a nucleating agent and a heat stabilizer to obtain a blank; immersing the blank into a foaming gas for foaming to obtain a foamed body; and subjecting the foamed body to crosslinking curing to obtain a crosslinked polyvinyl chloride structure foamed material. According to the present invention, the crosslinked polyvinyl chloride structure foamed material is prepared by means of a brand-new process route, and the composition and proportion of the PVC resin and other raw materials can be adjusted in a wide range; and carbon dioxide or nitrogen is used for foaming. Further provided is a crosslinked polyvinyl chloride structure foamed material.

Abstract: Image processing for scanning devices based on laser aimer position, wherein a first frame and a second frame of image data related to an object associated with a barcode are captured using a scanning device. A difference between first pixel data for a first grouping of pixels associated with the first frame and second pixel data for a second grouping of pixels associated with the second frame is computed. Additionally, a location of a laser aimer pattern in the first frame or the second frame is determined based on a comparison between respective differences between the first pixel data for the first grouping of pixels and the second pixel data for the second grouping of pixels, where the laser aimer pattern is created by the scanning device.

Abstract: A light guide module includes a cover plate, a light-shielding layer, a light guide plate, and at least one light source. The light-shielding layer is disposed under the cover plate and has a width less than about 4 mm. The light guide plate is disposed under the cover plate. The light guide plate has a reflective surface and a light-exiting surface opposite to each other, and a light-incident surface and three side surfaces connected between the reflective surface and the light-exiting surface. The light source is configured to emit light toward the light-incident surface. A surface roughness of the three side surfaces ranges from about 300 nm to about 400 nm, so that a change rate of brightness measured by any adjacent two of measuring points evenly distributed on the light-exiting surface is between about 8% and about 12%.

Abstract: A light guide module includes a cover plate, a light-shielding layer, a light guide plate, and at least one light source. The light-shielding layer is disposed under the cover plate and has a width less than about 4 mm. The light guide plate is disposed under the cover plate. The light guide plate has a reflective surface and a light-exiting surface opposite to each other, and a light-incident surface and three side surfaces connected between the reflective surface and the light-exiting surface. The light source is configured to emit light toward the light-incident surface. A surface roughness of the three side surfaces ranges from about 300 nm to about 400 nm, so that a change rate of brightness measured by any adjacent two of measuring points evenly distributed on the light-exiting surface is between about 8% and about 12%.

Abstract: The disclosed embodiments disclose techniques for accessing a scale-out block interface in a cloud-based distributed computing environment (CBDCE). During operation, an instance of a block device service (BDS) receives a data request from a client. The BDS instance translates the data request into a set of data block accesses, and then sends the translated data request to a data processing layer service (DPL). The DPL instance services the data request using a set of data operations that leverage one or more of a distributed cache, a distributed database, and a cloud storage system. The BDS service leverages the DPL instance to provide to the client an abstraction of a highly-available block storage device with unlimited storage space via the scale-out block interface.

Abstract: The disclosed embodiments disclose techniques for journaling data received in a cloud-based distributed computing environment (CBDCE). Multiple services simultaneously execute on the CBDCE compute nodes, with each service comprising multiple service instances that simultaneously execute on multiple, distinct compute nodes of the CBDCE. The CBDCE includes a distributed database that enables coordination between the service instances of services that execute in the CBDCE; this distributed database also includes multiple distributed database instances that simultaneously executing on multiple different CBDCE compute nodes. During operation, a service instance executing on one of these compute nodes receives a client request. The service instance submits this client request to a distributed database instance and, in parallel, also submits the client request and its associated user data to a distributed journaling service.

Abstract: Benzyl derivative compounds having peroxisome proliferator-activated receptor ? (PPAR?) agonistic activity, kits and compositions containing such compounds, and methods of their use in enhancing PPAR? activity for treating diseases and/or conditions involving inflammation and/or angiogenesis, particularly ocular diseases and/or conditions such as but not limited to retinal inflammation, retinal neovascularization, retinal vascular leakage, retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, and diabetic macular edema.

Abstract: The disclosed embodiments disclose techniques for managing a distributed cache in a cloud-based distributed computing environment (CBDCE). During operation, an instance of a data processing layer service (DPL) receives a data request from a client that specifies an address and an operation for a target data block. The DPL instance uses these to determine a first cache instance of the distributed cache that is assigned to cache a metadata entry that links the address with a data block fingerprint for the target data block. The DPL instance then uses the data block fingerprint and the cache mapping to determine a second cache instance that is assigned to store the target data block, and then accesses the second cache instance to complete the operation for the target data block.

Abstract: The disclosed embodiments disclose techniques for managing a cloud-based distributed computing environment (CBDCE) that comprises multiple geographically-distributed compute nodes. Multiple services simultaneously execute on the CBDCE compute nodes, with each service comprising multiple service instances that simultaneously execute on multiple distinct compute nodes of the CBDCE. During operation, the system uses a distributed database to track the status of the CBDCE to ensure the ongoing stability and scalability of the CBDCE. Upon receiving a request that is associated with the configuration of the CBDCE, a service accesses CBDCE status information from the distributed database to respond to the request.

Abstract: Benzyl derivative compounds having peroxisome proliferator-activated receptor ? (PPAR?) agonistic activity, compositions containing such compounds, and methods of their use in enhancing PPAR? activity for treating diseases and/or conditions involving inflammation and/or angiogenesis, particularly ocular diseases and/or conditions such as but not limited to retinal inflammation, retinal neovascularization, retinal vascular leakage, retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, and diabetic macular edema are disclosed.

Abstract: Pharmaceutical particles having an inner portion comprising an agonist of peroxisome proliferator-activated receptor ? (PPAR?) and a biodegradable polymer; and an outer coating comprising an emulsifier which surrounds the inner portion, wherein the agonist may be a fibrate, and the particle contains at least about 5 wt % to about 25 wt % of the agonist, and wherein the particle has a sustained delayed release of the agonist in a range of at least about 1 to 12 months when in an aqueous solution or physiological environment. The pharmaceutical particles may be used, for example, to treat diseases and conditions such as ocular disorders which benefit from PPAR? agonism.

Abstract: Compositions containing a phenylquinoline derivative compound having peroxisome proliferator-activated receptor a (PPAR?) agonistic activity, and methods of their use in enhancing PPAR? activity in retinal cells, and in treating ocular disorders or conditions, such as but not limited to retinal inflammation, retinal neovascularization, retinal vascular leakage, retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, and diabetic macular edema are disclosed.

Abstract: The disclosed embodiments disclose techniques for managing cloud-based storage using a time-series database. A distributed cloud data management system (DCDMS) manages objects stored in a cloud storage system. The DCDMS leverages a distributed time-series database to track objects accessed via the DCDMS. During operation, the DCDMS receives a request to access an object using a path identifier and an object identifier. The DCDMS determines from the path identifier that the request is associated with one of its supported extended capabilities, and uses the previously tracked object operations that are stored in the time-series database to determine the actual target bucket in the cloud storage system that contains the requested object; the target bucket that contains the object may be different from the bucket identified in the path identifier that is received. The object identifier is then used to access the requested object from the target bucket to service the request.

Abstract: A structural non-gradient topology optimization method based on a sequential Kriging surrogate model mainly comprises three parts: reduced series expansion of a material field of design domain, building of a non-gradient topology optimization model and solving optimization model using a sequential Kriging surrogate model algorithm. Design variables of the topology optimization problem are considerably reduced through the series expansion of a material-field function, and then the topology optimization problem involving fewer than 50 design variables can be effectively solved using the sequential Kriging surrogate model algorithm with an adaptive design space adjustment strategy. Without requiring the information of design sensitivity of a performance function, this method is suitable for solving complex multi-physical, multidisciplinary and highly nonlinear topology optimization problems.

Abstract: Benzyl derivative compounds having peroxisome proliferator-activated receptor ? (PPAR?) agonistic activity, compositions containing such compounds, and methods of their use in enhancing PPAR? activity for treating diseases and/or conditions involving inflammation and/or angiogenesis, particularly ocular diseases and/or conditions such as but not limited to retinal inflammation, retinal neovascularization, retinal vascular leakage, retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, and diabetic macular edema are disclosed.

Abstract: The present invention relates to a system and method for providing a failover of storage for media content, including media content used for broadcasting in cinema. One embodiment of the invention stores copies of digital cinema packages (“DCPs”) to both a central storage facility as well as a local storage facility. When a server module reading DCPs in central storage module encounters abnormalities, it switches reading operations to the local storage module, at the same frame location from which interruption occurred. The present invention provides a multi-layered storage system for cinema broadcasting of a movie to decrease likelihood of interruptions during a broadcast that may be caused by failure of the central storage facility.

Abstract: Pharmaceutical particles having an inner portion comprising an agonist of peroxisome proliferator-activated receptor ? (PPAR?) and a biodegradable polymer; and an outer coating comprising an emulsifier which surrounds the inner portion, wherein the agonist may be a fibrate, and the particle contains at least about 5 wt % to about 25 wt % of the agonist, and wherein the particle has a sustained delayed release of the agonist in a range of at least about 1 to 12 months when in an aqueous solution or physiological environment. The pharmaceutical particles may be used, for example, to treat diseases and conditions such as ocular disorders which benefit from PPAR? agonist.