Patents by Inventor Jian Yuan Luo

Jian Yuan Luo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sir2a-based therapeutic and prophylactic methods
    Publication number: 20080119434
    Abstract: This invention provides methods for treating and for inhibiting the onset of cancer in a subject comprising administering an agent that inhibits the ability of Sir2? to inhibit p53-dependent apoptosis. This invention also provides a related method for inducing the death of a cell. This invention further provides a method for decreasing the amount of damage to a subject's cells caused by physical stress comprising administering agent that increases the amount of Sir2? in the subject's cells and/or the ability of Sir2? to inhibit p53-dependent apoptosis in the subject's cells. This invention further provides related methods for prolonging the life-span of a subject, decreasing the amount of damage to a cell caused by physical stress, and prolonging the life-span of a cell. Finally, this invention provides two articles of manufacture for performing the instant methods.
    Type: Application
    Filed: July 9, 2007
    Publication date: May 22, 2008
    Applicant: The Trustees of Colubia University
    Inventors: Wei Gu, Jian Yuan Luo
  • Sir2?-based therapeutic and prophylactic methods
    Patent number: 7241743
    Abstract: This invention provides methods for treating and for inhibiting the onset of cancer in a subject comprising administering an agent that inhibits the ability of Sir2? to inhibit p53-dependent apoptosis. This invention also provides a related method for inducing the death of a cell. This invention further provides a method for decreasing the amount of damage to a subject's cells caused by physical stress comprising administering agent that increases the amount of Sir2? in the subject's cells and/or the ability of Sir2? to inhibit p53-dependent apoptosis in the subject's cells. This invention further provides related methods for prolonging the life-span of a subject, decreasing the amount of damage to a cell caused by physical stress, and prolonging the life-span of a cell. Finally, this invention provides two articles of manufacture for performing the instant methods.
    Type: Grant
    Filed: June 14, 2002
    Date of Patent: July 10, 2007
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Wei Gu, Jian Yuan Luo
  • Sir2alpha-based therapeutic and prophylactic methods
    Publication number: 20030124101
    Abstract: This invention provides methods for treating and for inhibiting the onset of cancer in a subject comprising administering an agent that inhibits the ability of Sir2&agr; to inhibit p53-dependent apoptosis. This invention also provides a related method for inducing the death of a cell. This invention further provides a method for decreasing the amount of damage to a subject's cells caused by physical stress comprising administering agent that increases the amount of Sir2&agr; in the subject's cells and/or the ability of Sir2&agr; to inhibit p53-dependent apoptosis in the subject's cells. This invention further provides related methods for prolonging the life-span of a subject, decreasing the amount of damage to a cell caused by physical stress, and prolonging the life-span of a cell. Finally, this invention provides two articles of manufacture for performing the instant methods.
    Type: Application
    Filed: June 14, 2002
    Publication date: July 3, 2003
    Inventors: Wei Gu, Jian Yuan Luo