Abstract: Provided is a masking peptide for an antibody or antigen-binding fragment thereof. Also provided are polypeptides (e.g., antibody masks) that block the binding between an antibody (e.g., an anti-CD3 antibody) and its target, fusion proteins, and protein constructs and uses thereof.

Abstract: Provided are multispecific antibodies (e.g., bispecific antibodies) or antigen-binding fragments thereof. In one aspect, the multispecific antibodies or antigen-binding fragments thereof can bind to a T cell antigen (e.g., CD3) and/or a tumor-associated antigen (e.g., CEACAM5), or a combination thereof.

Abstract: A full-automatic sample pretreatment device includes a frame module, a cap removing module, a blood-collection tube grasping module, a pipette module, a platform module, a handling module, a film sealing module, a magnetic solid phase extraction module, an SPE positive pressure extraction module and a conveyor belt waste transfer module. A conveyor belt waste transfer module is arranged at a bottom of the frame module, the cap removing module, the platform module and the magnetic solid phase extraction module are sequentially arranged in the middle of the frame module from left to right, and the blood-collection tube grasping module, the pipette module, the handling module and the film sealing module are arranged at an upper portion of the frame module. The magnetic solid phase extraction module and the SPE positive pressure extraction module are detachable and interchangeable components.

Abstract: The present invention relates to a mass spectrometry device containing an ion transport channel. The ion transport channel is a gradual ion transport channel, an inner diameter of the ion transport channel is gradually reduced, the strength of an electric field formed in the channel is gradually enhanced, and an area of an effective electric field is gradually reduced. Such a device allows ions to be transported stably in the transport channel and increasingly aggregated, thereby reducing the loss of ions, improving the sensitivity and resolution of later detection, and reducing the cost of the device.

Abstract: A methylation detection method and kit for genomic DNA or cell-free DNA molecules in a biological sample are provided. The method includes: obtaining a converted DNA molecule through a chemical and/or enzymatic reaction; performing a methylation-specific multiplex PCR, through multiple pairs of methylation-specific primers, on one or more methylated areas of one or more genes in the converted DNA molecule serving as a substrate, in order to obtain a PCR amplification product; and detecting the methylation levels of different fragments of the amplification product. The detection method can detect DNA methylation in multiple genes in multiple samples at the same time, requires only a small initial amount of DNA, is suitable for detecting methylated fragments having a small copy number, and has such advantages as high sensitivity, high specificity, high accuracy, a low detection limit, and low detection cost.

Abstract: Embodiments of this application provide a method for subscribing to event streams. The method includes: A first device generates a first message used to subscribe to event streams, where the first message includes a group identifier, and the group identifier corresponds to a plurality of event streams; and the first device sends the first message to a second device, to obtain data of the plurality of event streams corresponding to the group identifier.

Abstract: This application provides a status notification method, an optical module, a network device, and a network system. The method includes: determining a lock status of a logical lane in a first optical module, where the first optical module belongs to a first network device, and the lock status includes a locked state or an unlocked state; and sending uplink notification information when the lock status indicates that the logical lane in the first optical module is locked, where the uplink notification information is used to enable a second optical module to determine that the logical lane in the first optical module is locked, the second optical module belongs to a second network device, and the first optical module is connected to the second optical module.

Abstract: A first server device obtains first device information of the first server device. The first device information may include an event or a device identifier. The first server device determines a first condition corresponding to the first device information of the first server device, and performs a first processing action corresponding to the first device information when determining that the first device information meets the first condition.

Abstract: This disclosure provides an encryption/decryption system, an optical module, and a related apparatus and system, and belongs to the field of network communications technologies. The encryption/decryption system includes an encryption/decryption component, a first interface component, and a second interface component. The encryption/decryption component is configured to encrypt a first physical layer data stream from the first interface component and transmit the encrypted first physical layer data stream to the second interface component, and is configured to decrypt a second physical layer data stream from the second interface component and transmit the decrypted second physical layer data stream to the first interface component. According to this disclosure, a delay caused by encryption/decryption during data transmission can be reduced.

Abstract: A packet transmission method is applied to a communication device including a first MPU, a second MPU, and an LPU. The first MPU is connected to the LPU through a first transmission channel. The second MPU is connected to the LPU through a second transmission channel. During packet transmission, a service flow packet is transmitted through the first transmission channel, and a non-service flow packet is transmitted through the second transmission channel. Therefore, the service flow packet and the non-service flow packet are processed by different MPUs, so that the service flow packet and the non-service flow packet do not compete with each other. In this way, transmission efficiency of the non-service flow packet is improved. In addition, when the first MPU is attacked by an abnormal service flow packet, the second MPU is not affected, and may normally perform operation and maintenance management.

Abstract: Embodiments of this application disclose a data obtaining method. A first device serving as a network management device may generate a first message including a first keyword. The first message is used to indicate a second device to determine a first path in which the second device stores a parameter determined by the first keyword, and send the first path to the first device. The second device may be a device managed by the first device. Then, the first device may send the first message to the second device. After receiving the first message, the second device may determine the first path in which the second device stores the parameter determined by the first keyword, add the determined first path to a second message, and send the second message to the first device.

Abstract: An energy conservation management method includes selecting, by a policy server, a target scenario model from a plurality of scenario models based on a plurality of scenario attribute values of a target network, and configuring, by the policy server, a network device in the target network based on an energy conservation policy of the target scenario model. At least one of the plurality of scenario attribute values is an attribute value of a scenario attribute related to a network power consumption of the target network. The at least one of the plurality of scenario attribute values includes a plurality of attribute values of a corresponding scenario attribute, wherein each of the plurality of attribute values is collected at a different time from other attribute values of the plurality of attribute values that are collected at different times.

Abstract: A system for implementing service function deployment includes an active apparatus and a standby apparatus for a first service, such as an active main processing unit (MPU) and a standby MPU. The active apparatus is configured to process the first service and deploy a first function module (such as a feature extraction module or an inference module) for a second service (such as an artificial intelligence (AI) service) on the standby apparatus. The standby apparatus is configured to process data of the second service by using the first function module. The second service may be implemented by using an idle resource of the standby apparatus for the first service.

Abstract: Embodiments of this application provide a method for subscribing to event streams. The method includes: A first device generates a first message used to subscribe to event streams, where the first message includes a group identifier, and the group identifier corresponds to a plurality of event streams; and the first device sends the first message to a second device, to obtain data of the plurality of event streams corresponding to the group identifier.

Abstract: A first server device obtains first device information of the first server device. The first device information may include an event or a device identifier. The first server device determines a first condition corresponding to the first device information of the first server device, and performs a first processing action corresponding to the first device information when determining that the first device information meets the first condition.

Abstract: The present application provides a reusable powered endoscopic cutter stapler, comprising a controller, a handle, an adapter and a cable component; the adapter is connected with the handle; one end of the cable component is detachably connected with the controller, the other end is detachably connected with the handle to be used for transmitting electric energy and command signals; the controller can be reused for many times, and the cable component can be reused for many times after being sterilized. According to the reusable powered endoscopic cutter stapler disclosed by the present application, at least one or multiple components of a core component can be sterilized repeatedly, and can be used for many times, thereby not only greatly lowering the treatment expense of patients, but also greatly reducing the risk of cross infection when instruments are used, improving the use safety and reliability of the instruments, and greatly lightening the overall mass, so that a doctor can operate more conveniently.

Abstract: An energy conservation management method includes selecting, by a policy server, a target scenario model from a plurality of scenario models based on a plurality of scenario attribute values of a target network, and configuring, by the policy server, a network device in the target network based on an energy conservation policy of the target scenario model. At least one of the plurality of scenario attribute values is an attribute value of a scenario attribute related to a network power consumption of the target network. The at least one of the plurality of scenario attribute values includes a plurality of attribute values of a corresponding scenario attribute, wherein each of the plurality of attribute values is collected at a different time from other attribute values of the plurality of attribute values that are collected at different times.

Abstract: The present invention discloses a mixed herbicide containing aminopyralid and clomazone, which belongs to the technical field of pesticides. The main active ingredients in the herbicide are aminopyralid and clomazone, and the weight ratio of aminopyralid to clomazone is 0.1-80:0.1-80. The present mixed herbicide is useful in weed control in non-arable land, orchards, woodland, corn fields, and rapeseed fields, and has the advantages of quick action, broad herbicidal spectrum, long-lasting effect, thorough weed eradication, low residue, low toxicity, safety, and environmental friendliness, thus being a good chemical herbicide for non-arable land, orchards, woodland, corn fields, and rapeseed fields.

Abstract: The present invention discloses a mixed herbicide containing aminopyralid and clomazone, which belongs to the technical field of pesticides. The main active ingredients in the herbicide are aminopyralid and clomazone, and the weight ratio of aminopyralid to clomazone is 0.1-80:0.1-80. The present mixed herbicide is useful in weed control in non-arable land, orchards, woodland, corn fields, and rapeseed fields, and has the advantages of quick action, broad herbicidal spectrum, long-lasting effect, thorough weed eradication, low residue, low toxicity, safety, and environmental friendliness, thus being a good chemical herbicide for non-arable land, orchards, woodland, corn fields, and rapeseed fields.