Abstract: A detachable electric fireplace includes a base, at least one artificial firewood assembly detachably disposed on a top of the base, at least one light source assembly detachably disposed on the base, and a flame simulation assembly disposed inside the base. The at least one artificial firewood assembly includes a firewood support and an artificial firewood. The firewood support is detachably disposed on the base. A light-transmitting hole is defined on the firewood support. The artificial firewood is detachably disposed on the firewood support and is disposed above the light-transmitting hole. The artificial firewood is a light-transmitting hollow structure. The at least one light source assembly is disposed below the light-transmitting hole. Light emitted by the at least one light source assembly penetrates through the light-transmitting hole to light up the artificial firewood. The detachable electric fireplace is able to be disassembled for storage.

Abstract: In various aspects and embodiments the invention provides a method of treating epilepsy in a subject in need thereof the method comprising contacting a target cell of the subject with an effective amount of an HCN4 disrupting agent.