Abstract: The present invention belongs to animal experiments field, disclosed a single factor modeling-constraint method and device for mice chronic fatigue syndrome, the modeling-constraint method is specifically using mineral water bottle to restraint mice; the mineral water bottle is divided into upper, middle and lower parts; the body of mineral water bottle is uniformly drilled for mice to breathe; the inner of the mineral water bottle is blocked by a cardboard to reduce the move space of mice; cover the mice through the divided bottle; one end of the opening is tightly attach to the wall, the other end is tightly attach to the mice feeding box, and keeping 30 minutes to restraint. The present invention utilizes mineral water bottle to make three simple restraint tube, not only saves the costs of experiment, but also turns waste into treasure, which is a simple operation, and increases the possibility of the experiment.

Abstract: A high-efficiency yield-increasing exploitation method for natural gas hydrates includes steps of drilling of natural gas hydrate reservoirs along horizontal wells, seepage increasing by fracturing for fracture forming and stability improvement by grouting in the natural gas hydrate reservoirs, and yield improvement by combined exploitation of depressurization of the horizontal wells and heat injection; according to the present invention, drilling time is shortened by rapid drilling along the horizontal wells, the permeability of the reservoirs can be effectively improved by fracturing for fracture forming, the stability of the reservoirs can be improved by injecting foam cement slurry into the reservoirs, and the yield of the natural gas hydrates can be improved by the combined exploitation method of depressurization of the horizontal wells and heat injection.

Abstract: A high-efficiency yield-increasing exploitation method for natural gas hydrates includes steps of drilling of natural gas hydrate reservoirs along horizontal wells, seepage increasing by fracturing for fracture forming and stability improvement by grouting in the natural gas hydrate reservoirs, and yield improvement by combined exploitation of depressurization of the horizontal wells and heat injection; according to the present invention, drilling time is shortened by rapid drilling along the horizontal wells, the permeability of the reservoirs can be effectively improved by fracturing for fracture forming, the stability of the reservoirs can be improved by injecting by the combined exploitation method of depressurization of the horizontal wells and heat injection.