Patents by Inventor Jianchao Wang

Jianchao Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ?-(Trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl)-trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetic agents
    Patent number: 7371888
    Abstract: Compounds having a formula: or a pharmaceutically acceptable salt or prodrug thereof, are provided, and are useful for the treatment of metabolic disorders.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: May 13, 2008
    Assignee: Metabolex, Inc.
    Inventors: Zuchun Zhao, Xin Chen, Jianchao Wang, Hongbin Sun, Jack Shih-Chieh Liang
  • Certain chemical entities, compositions, and methods
    Publication number: 20070197481
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
    Type: Application
    Filed: May 6, 2005
    Publication date: August 23, 2007
    Inventors: Xiangping Qian, Andrew McDonald, Han-Jie Zhou, Luke Ashcraft, Bing Yao, Hong Jiang, Jennifer Kuo Chen Huang, Jianchao Wang, David Morgans, Bradley Morgan, Gustave Bergnes, Dashyant Dhanak, Steven Knight, Nicholas Adams, Cynthia Parrish, Kevin Duffy, Duke Fitch, Rosanna Tedesco
  • Certain chemical entities, compositions, and methods
    Publication number: 20070161674
    Abstract: Compounds useful for treating cellular proliferative diseases are disclosed.
    Type: Application
    Filed: November 15, 2006
    Publication date: July 12, 2007
    Inventors: Scott Collibee, Zhe Yang, Luke Ashcraft, Gustave Bergnes, Bradley Morgan, David Morgans, Jianchao Wang
  • Certain chemical entities, compositions, and methods
    Publication number: 20070149516
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
    Type: Application
    Filed: November 8, 2006
    Publication date: June 28, 2007
    Inventors: Xiangping Qian, Luke Ashcraft, Jianchao Wang, Bing Yao, Hong Jiang, Gustave Bergnes, Bradley Morgan, David Morgans, Dashyant Dhanak, Steven Knight, Nicholas Adams, Cynthia Parrish, Kevin Duffy, Duke Fitch, Rosanna Tedesco
  • Certain chemical entities, compositions, and methods
    Publication number: 20070135435
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
    Type: Application
    Filed: November 1, 2006
    Publication date: June 14, 2007
    Inventors: Xiangping Qian, Jianchao Wang, Gustave Bergnes, Bradley Morgan, David Morgans, Martha Sarpong, Dashyant Dhanak, Steven Knight
  • Substituted phenylacetic acids
    Publication number: 20060264630
    Abstract: Substituted phenylacetic acids, phenylethanols and related compounds are provided that are useful in treating or controlling a number of diseases associated with glucose metabolism, lipid metabolism and insulin secretion.
    Type: Application
    Filed: January 4, 2006
    Publication date: November 23, 2006
    Applicant: Metabolex, Inc.
    Inventors: Zuchun Zhao, Xin Chen, Jianchao Wang, Hongbin Sun, Jack Liang
  • Certain chemical entities, compositions, and methods
    Publication number: 20060247289
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
    Type: Application
    Filed: November 9, 2005
    Publication date: November 2, 2006
    Inventors: Xiangping Qian, Andrew McDonald, Han-Jie Zhou, Luke Ashcraft, Bing Yao, Hong Jiang, Jennifer Kuo Chen Huang, Jianchao Wang, David Morgans, Bradley Morgan, Gustave Bergnes, Dashyant Dhanak, Steven Knight, Nicholas Adams, Cynthia Parrish, Kevin Duffy, Duke Fitch, Rosanna Tedesco
  • Substituted phenylacetic acids
    Patent number: 7078421
    Abstract: Substituted phenylacetic acids, phenylethanols and related compounds are provided that are useful in treating or controlling a number of diseases associated with glucose metabolism, lipid metabolism and insulin secretion.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: July 18, 2006
    Assignee: Metabolex, Inc.
    Inventors: Zuchun Zhao, Xin Chen, Jianchao Wang, Hongbin Sun, Jack Shih-Chieh Liang
  • Oligonucleotides having alkylphosphonate linkages and methods for their preparation
    Patent number: 7049432
    Abstract: The present invention provides alkylphosphonate dimers and oligonucleotides prepared therefrom. The invention further provides novel methods for the preparation of these alkylphosphonate dimers. Methods for the preparation of substantially diastereomerically pure alkylphosphonate dimers are also provided.
    Type: Grant
    Filed: June 4, 2002
    Date of Patent: May 23, 2006
    Assignees: ISIS Pharmaceuticals, Inc., McGill University
    Inventors: Muthiah Manoharan, George Just, Andrei Guzaev, Arlène Roland, Jianchao Wang, Michael E. Jung
  • Certain chemical entities, compositions, and methods
    Publication number: 20060094708
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
    Type: Application
    Filed: May 3, 2005
    Publication date: May 4, 2006
    Inventors: Xiangping Qian, Andrew McDonald, Han-Jie Zhou, Luke Ashcraft, Bing Yao, Hong Jiang, Jennifer Chen Huang, Jianchao Wang, David Morgans, Bradley Morgan, Gustave Bergnes, Dashyant Dhanak, Steven Knight, Nicholas Adams, Cynthia Parrish
  • Alpha(trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl)-trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetic agents
    Publication number: 20050222213
    Abstract: Compounds having a formula: or a pharmaceutically acceptable salt or prodrug thereof, are provided, and are useful for the treatment of metabolic disorders.
    Type: Application
    Filed: February 17, 2005
    Publication date: October 6, 2005
    Applicant: Metabolex, Inc.
    Inventors: Zuchun Zhao, Xin Chen, Jianchao Wang, Hongbin Sun, Jack Liang
  • Preparation of phosphorothioate oligomers
    Patent number: 6861518
    Abstract: Methods and Intermediates for the Preparation of Oligomers Containing Diastereomerically Enriched Phosphorothioate Linkages are Disclosed.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: March 1, 2005
    Assignee: McGill University
    Inventors: George Just, Zhili Xin, Eric Marsault, Yi Jin, Jianchao Wang
  • Substituted phenylacetic acids
    Publication number: 20040029933
    Abstract: Substituted phenylacetic acids, phenylethanols and related compounds are provided that are useful in treating or controlling a number of diseases associated with glucose metabolism, lipid metabolism and insulin secretion.
    Type: Application
    Filed: March 19, 2003
    Publication date: February 12, 2004
    Applicant: Metabolex, Inc.
    Inventors: Zuchun Zhao, Xin Chen, Jianchao Wang, Hongbin Sun, Jack Shih-Chieh Liang
  • Preparation of phosphorothioate oligomers
    Publication number: 20030114660
    Abstract: Methods and Intermediates for the Preparation of Oligomers Containing Diastereomerically Enriched Phosphorothioate Linkages are Disclosed.
    Type: Application
    Filed: September 24, 2002
    Publication date: June 19, 2003
    Inventors: George Just, Zhili Xin, Eric Marsault, Yi Jin, Jianchao Wang
  • Oligonucleotides having alkylphosphonate linkages and methods for their preparation
    Publication number: 20030078414
    Abstract: The present invention provides alkylphosphonate dimers and oligonucleotides prepared therefrom. The invention further provides novel methods for the preparation of these alkylphosphonate dimers. Methods for the preparation of substantially diastereomerically pure alkylphosphonate dimers are also provided.
    Type: Application
    Filed: June 4, 2002
    Publication date: April 24, 2003
    Applicant: Isis Pharmaceuticals, Inc.
    Inventors: Muthiah Manoharan, George Just, Andrei Guzaev, Arlene Roland, Jianchao Wang, Michael E. Jung
  • Oligonucleotides having alkylphosphonate linkages and methods for their preparation
    Patent number: 6486313
    Abstract: The present invention provides alkylphosphonate dimers and oligonucleotides prepared therefrom. The invention further provides novel methods for the preparation of these alkylphosphonate dimers. Methods for the preparation of substantially diastereomerically pure alkylphosphonate dimers are also provided.
    Type: Grant
    Filed: February 18, 1999
    Date of Patent: November 26, 2002
    Assignees: ISIS Pharmaceuticals, Inc., McGill University
    Inventors: Muthiah Manoharan, George Just, Andrei Guzaev, Arlène Roland, Jianchao Wang, Michael E. Jung
  • Preparation of phosphorothioate oligomers
    Patent number: 6476216
    Abstract: The present invention is directed to methods for solid phase nucleotide synthesis utilizing substituted imidazole catalysts.
    Type: Grant
    Filed: December 3, 1998
    Date of Patent: November 5, 2002
    Assignee: McGill University
    Inventors: George Just, Zhili Xin, Eric Marsault, Yi Jin, Jianchao Wang
  • Method and apparatus for constructing a latin square matrix for network communication
    Patent number: 6456620
    Abstract: Disclosed is a method for all-to-all personalized exchange for a class of multistage interconnecting networks (MINs). The method is based on a Latin square matrix corresponding to a set of admissible permutations of a multistage interconnecting network. Disclosed are first and second methods for constructing a Latin square matrix used in the personalized exchange technique. Also disclosed is a generic method for decomposing all-to-all personalized exchange patterns into admissible permutations to form the Latin square matrix for self-routing networks which are a subclass of the MINs.
    Type: Grant
    Filed: February 17, 1999
    Date of Patent: September 24, 2002
    Assignees: Verizon Laboratories Inc., The University of Vermont
    Inventors: Jianchao Wang, Yuanyuan Yang
  • Generic approach to generating permutations for all-to-all personalized exchange for self-routing multistage interconnection networks
    Patent number: 6456838
    Abstract: Disclosed is a method for all-to-all personalized exchange for a class of multistage interconnecting networks (MINs). The method is based on a Latin square matrix corresponding to a set of admissible permutations of a multistage interconnecting network. Disclosed are first and second methods for constructing a Latin square matrix used in the personalized exchange technique. Also disclosed is a generic method for decomposing all-to-all personalized exchange patterns into admissible permutations to form the Latin square matrix for self-routing networks which are a subclass of the MINs.
    Type: Grant
    Filed: February 17, 1999
    Date of Patent: September 24, 2002
    Assignees: Verizon Laboratories Inc., The University of Vermont
    Inventors: Jianchao Wang, Yuanyuan Yang
  • 14-membered macrolides derived from leucomycins
    Publication number: 20020128212
    Abstract: There is described a novel class of ring contracted 14-membered macrolides, and pharmaceutically acceptable salts, esters and prodrugs thereof, having antibacterial activity, compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier as well as a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention.
    Type: Application
    Filed: December 22, 2000
    Publication date: September 12, 2002
    Inventors: Yat Sun Or, Tsvetelina Lazarova, Sophie Binet, Jianchao Wang