Patents by Inventor Jianfa Zhang

Jianfa Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240000993
    Abstract: The present disclosure provides a Paenibacillus strain, and a hemostatic polysaccharide produced by same and use thereof. In the present disclosure, a Paenibacillus sp. 1229 has a deposit number of CCTCC NO: M 2022553. A produced exopolysaccharide (EPS) Hemoadhican has a hemostatic function, and can be prepared as a hemostatic material in different dosage forms for different types of hemostasis. The hemostatic material has a high hemostatic speed, no need for applying pressures to the wound for a long time, safety and non-toxicity, desirable biocompatibility, and no requirement of removal after use. The material is suitable for the application of hemostasis in irregular bleeding such as solid organs in vitro or in vivo and diffuse bleeding.
    Type: Application
    Filed: May 12, 2023
    Publication date: January 4, 2024
    Applicant: Nanjing Southern Element Biotechnology Co., Ltd.
    Inventors: Jianfa ZHANG, Changchang KONG, Shijunyin CHEN, Bing LI
  • Patent number: 11819514
    Abstract: Oligosaccharide riclinoctaose is used in preparation of a drug for treating and/or preventing ischemia-reperfusion injury (IRI). The oligosaccharide riclinoctaose has a structural formula as follows: The oligosaccharide riclinoctaose can significantly relieve postoperative liver injury, kidney injury, and brain injury in ischemia-reperfusion mice.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: November 21, 2023
    Assignee: Nanjing Southern Element Biotechnology Co., Ltd.
    Inventors: Jianfa Zhang, Ni Wang, Yang Zhao
  • Publication number: 20230303724
    Abstract: The present disclosure provides a heteropoly oligosaccharide and an application thereof in improving plant disease resistance. The heteropoly oligosaccharide includes seven D-glucose residues and one D-galactose residue.
    Type: Application
    Filed: April 7, 2023
    Publication date: September 28, 2023
    Inventors: Jianfa ZHANG, Renjie FU, Jing LI, Rui CHENG
  • Publication number: 20230144882
    Abstract: The present disclosure provides use of adenosine deaminase (ADA) and an ADA modifier in preparation of a medicament for wound repair in a patient with diabetes. It is found for the first time that the ADA (EC 3.5.4.4) and a polyethylene glycol-modified adenosine deaminase (PEG-ADA) have a significant improvement effect on wound repair of type-2 diabetic mice, and the ADA or the ADA modifier can be developed into a medicament for treating diabetic wounds.
    Type: Application
    Filed: November 8, 2022
    Publication date: May 11, 2023
    Inventors: Jianfa Zhang, Tongyuan Lu
  • Publication number: 20230054546
    Abstract: Oligosaccharide riclinoctaose is used in preparation of a drug for treating and/or preventing ischemia-reperfusion injury (IRI). The oligosaccharide riclinoctaose has a structural formula as follows: The oligosaccharide riclinoctaose can significantly relieve postoperative liver injury, kidney injury, and brain injury in ischemia-reperfusion mice.
    Type: Application
    Filed: August 2, 2022
    Publication date: February 23, 2023
    Inventors: Jianfa ZHANG, Ni WANG, Yang ZHAO
  • Patent number: 9594262
    Abstract: First and second coherent light beams of the same wavelength are propagated in opposite directions to interact on a sub-wavelength thickness metallic metamaterial layer which is structured with a periodicity such that there is a resonance matched to the wavelength of the coherent beams. The first beam is then able to modulate the intensity of the second beam by modulating the phase and/or intensity of the first beam. The interference of the counter- propagating beams can eliminate or substantially reduce Joule loss of light energy in the metamaterial layer or, on the contrary, can lead to a near total absorption of light, depending on the mutual phase and/or intensity of the interacting beams. A modulation is thus provided without using a non-linear effect.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: March 14, 2017
    Assignee: University of Southampton
    Inventors: Nikolay Ivanovich Zheludev, Kevin Francis MacDonald, Jianfa Zhang, David John Richardson
  • Publication number: 20150049377
    Abstract: First and second coherent light beams of the same wavelength are propagated in opposite directions to interact on a sub-wavelength thickness metallic metamaterial layer which is structured with a periodicity such that there is a resonance matched to the wavelength of the coherent beams. The first beam is then able to modulate the intensity of the second beam by modulating the phase and/or intensity of the first beam. The interference of the counter- propagating beams can eliminate or substantially reduce Joule loss of light energy in the metamaterial layer or, on the contrary, can lead to a near total absorption of light, depending on the mutual phase and/or intensity of the interacting beams. A modulation is thus provided without using a non-linear effect.
    Type: Application
    Filed: March 12, 2013
    Publication date: February 19, 2015
    Inventors: Nikolay Ivanovich Zheludev, Kevin Francis MacDonald, Jianfa Zhang, David John Richardson
  • Publication number: 20120293854
    Abstract: A non-linear optical device comprising a non-linear element made of a plasmonic material with a periodic structure having a period smaller than the wavelength of a non-linear process intrinsic to the plasmonic material. The plasmonic material is implemented as a gold film which is structured with a periodic array of asymmetric split ring slits. The metamaterial framework of the plasmonic material itself is used as the source of a strong and fast non-linearity. The cubic non-linear response is resonantly enhanced through the effect of the metamaterial structuring by more than two orders of magnitude and its sign and magnitude can be controlled by varying the metamaterial pattern.
    Type: Application
    Filed: May 16, 2012
    Publication date: November 22, 2012
    Inventors: Nikolay Ivanovich Zheludev, Eric Plum, Jun-Yu Ou, Kevin Macdonald, Andrey Nikolaenko, Jianfa Zhang, Mengxin Ren, Baohua Jia
  • Publication number: 20120015118
    Abstract: A method and a device are disclosed for changing the color of a metal surface in a given part of the electromagnetic spectrum. It is achieved by creating a surface relief as an array of raised or indented repeated elements without breaking the continuity of the metal surface. The characteristic size of the elements is smaller than the shortest wavelength in that part of spectrum. In particular, the method uses excitation of surface plasmons on the metal surface. The relief may be optionally covered by a layer of dielectric or semiconductor for further fixed or externally controlled change of the metal surface color. The device may be used to detect the intensity or color or phase of incident light. It may be used to detect another substance in proximity of the surface by changing the color or phase or intensity of reflected light.
    Type: Application
    Filed: July 13, 2011
    Publication date: January 19, 2012
    Inventors: Nikolay I. Zheludev, Kevin Francis MacDonald, Nikitas Papasimakis, Jianfa Zhang, Jun-Yu Ou
  • Publication number: 20110059916
    Abstract: The present invention relates to the discovery the 5?-AMP and analogues thereof can be used to induce a state of torpor or suspended animation in subjects, as exemplified by studies carried out in laboratory mice. In these studies; mice were injected with high doses of 5?-AMP, which was found to result in a decoupling of the animals' body temperature regulation mechanism accompanied by a reduction in the animals' core body temperature, which tended to lower towards the ambient environmental temperature. It was further discovered that the introduction of high levels of 5?-AMP resulted in an induction of fat regulation genes such as procolipase (Clps) in tissues and organs that do not normally express Clps, this in turn was accompanied by a shift in metabolism from a primarily glycolytic energy metabolism (which is inhibited at lower temperatures) to one that relied primarily on the liberation and metabolism of free fatty acids.
    Type: Application
    Filed: May 17, 2010
    Publication date: March 10, 2011
    Inventors: Cheng Chi Lee, Jianfa Zhang
  • Publication number: 20070213295
    Abstract: The present invention relates to the discovery the 5?-AMP and analogues thereof can be used to induce a state of torpor or suspended animation in subjects, as exemplified by studies carried out in laboratory mice. In these studies, mice were injected with high doses of 5?-AMP, which was found to result in a decoupling of the animals' body temperature regulation mechanism accompanied by a reduction in the animals' core body temperature, which tended to lower towards the ambient environmental temperature. It was further discovered that the introduction of high levels of 5?-AMP resulted in an induction of fat regulation genes such as procolipase (Clps) in tissues and organs that do not normally express Clps, this in turn was accompanied by a shift in metabolism from a primarily glycolytic energy metabolism (which is inhibited at lower temperatures) to one that relied primarily on the liberation and metabolism of free fatty acids.
    Type: Application
    Filed: January 16, 2007
    Publication date: September 13, 2007
    Inventors: Cheng Lee, Jianfa Zhang