Patents by Inventor Jianfeng Mou

Jianfeng Mou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic compound as a caspase inhibitor
    Patent number: 11434212
    Abstract: A compound represented by formula (I), a pharmaceutically acceptable salt or tautomer thereof, and an application of the compound as a caspase inhibitor.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: September 6, 2022
    Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Jianfeng Mou, Songliang Wu, Haiying He, Fengying Guo, Chuan Wang, Jie Li, Jian Li, Shuhui Chen
  • Bicyclic Compound as a Caspase Inhibitor
    Publication number: 20210332019
    Abstract: A compound represented by formula (I), a pharmaceutically acceptable salt or tautomer thereof, and an application of the compound as a caspase inhibitor.
    Type: Application
    Filed: January 23, 2018
    Publication date: October 28, 2021
    Inventors: Jianfeng MOU, Songliang WU, Haiying HE, Fengying GUO, Chuan WANG, Jie LI, Jian LI, Shuhui CHEN
  • Crystal of a caspase inhibitor
    Patent number: 11091450
    Abstract: Disclosed herein a crystal structure of a caspase inhibitor, and more specifically a crystal structure of an (S)-3-((S)-2-(5-(2-chlorophenyl)isoxazole-3-formylamide)proponamide)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)valeric acid, a preparation method therefor, a crystal polymer, a pharmaceutical composition and uses thereof. The compound A of formula (I) disclosed herein exhibits high crystal structure stability, low hygroscopicity, and advantageously shows physical properties, safety and metabolic stability while having relatively high pharmaceutical value.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: August 17, 2021
    Assignee: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
    Inventors: Songliang Wu, Jianfeng Mou, Haiying He
  • Caspase inhibitor and pharmaceutical composition, use and therapeutic method thereof
    Patent number: 10981860
    Abstract: Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: April 20, 2021
    Assignees: Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Medshine Discovery Inc.
    Inventors: Haiying He, Songliang Wu, Zhi Luo, Jianfeng Mou, Fengying Guo, Chuan Wang, Guoqing Li, Minggao Zeng, Shuhui Chen
  • A CRYSTAL OF A CASPASE INHIBITOR
    Publication number: 20210002235
    Abstract: Disclosed herein a crystal structure of a caspase inhibitor, and more specifically a crystal structure of an (S)-3-((S)-2-(5-(2-chlorophenyl)isoxazole-3-formylamide)proponamide)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)valeric acid, a preparation method therefor, a crystal polymer, a pharmaceutical composition and uses thereof. The compound A of formula (I) disclosed herein exhibits high crystal structure stability, low hygroscopicity, and advantageously shows physical properties, safety and metabolic stability while having relatively high pharmaceutical value.
    Type: Application
    Filed: March 13, 2019
    Publication date: January 7, 2021
    Inventors: Songliang Wu, Jianfeng Mou, Haiying He
  • CASPASE INHIBITOR AND PHARMACEUTICAL COMPOSITION, USE AND THERAPEUTIC METHOD THEREOF
    Publication number: 20190135733
    Abstract: Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.
    Type: Application
    Filed: May 11, 2017
    Publication date: May 9, 2019
    Inventors: Haiying He, Songliang Wu, Zhi Luo, Jianfeng Mou, Fengying Guo, Chuan Wang, Guoqing Li, Minggao Zeng, Shuhui Chen