Abstract: The present invention provides a method of identifying a subject as having an increased risk of having or developing aggressive prostate cancer, comprising detecting in the subject the presence of various polymorphisms associated with an increased risk of having or developing aggressive prostate cancer.

Abstract: A data processing method is disclosed, including: twiddling input data, so as to obtain twiddled data; pre-rotating the twiddled data by using a symmetric rotate factor, where the rotate factor is a·W4L2p+1, p=0, . . . , L/2?1, and a is a constant; performing a Fast Fourier (Fast Fourier Transform, FFT) transform of L/2 point on the pre-rotated data, where L is the length of the input data; post-rotating the data that has undergone the FFT transform by using a symmetric rotate factor, where the rotate factor is b·W4L2q+1, q=0, . . . , L/2?1, and b is a constant; and obtaining output data.

Abstract: The invention relates to a method for determining an encoding parameter for an audio channel signal of a multi-channel audio signal, the method comprising: determining for the audio channel signal a set of functions from the audio channel signal and a reference audio signal; determining a first set of encoding parameters based on a smoothing of the set of functions with respect to a frame sequence of the multi-channel audio signal, the smoothing being based on a first smoothing coefficient; determining a second set of encoding parameters based on a smoothing of the set of functions with respect to the frame sequence of the multi-channel audio signal, the smoothing being based on a second smoothing coefficient; and determining the encoding parameter based on a quality criterion with respect to the first set of encoding parameters and/or the second set of encoding parameters.

Abstract: The invention relates to a method for determining an encoding parameter for an audio channel signal of a multi-channel audio signal, the method comprising: determining a frequency transform of the audio channel signal; determining a frequency transform of a reference audio signal; determining inter channel differences for at least each frequency sub-band of a subset of frequency sub-bands, each inter channel difference indicating a phase difference or time difference between a band-limited signal portion of the audio channel signal and a band-limited signal portion of the reference audio signal in the respective frequency sub-band the inter-channel difference is associated to; determining a first average based on positive values of the inter-channel differences and determining a second average based on negative values of the inter-channel differences; and determining the encoding parameter based on the first average and on the second average.

Abstract: The invention relates to a parametric audio encoder, comprising a parameter generator, the parameter generator being configured to determine a first set of encoding parameters and reference audio signal values, wherein the reference audio signal is another audio channel signal or a downmix audio signal derived from at least two audio channel signals of the plurality of multi-channel audio signals, to determine a first encoding parameter average based on the first set of encoding parameters of the audio channel signal, to determine a second encoding parameter average based on the first encoding parameter average of the audio channel signal and at least one other first encoding parameter average of the audio channel signal, and to determine the encoding parameter based on the first encoding parameter average of the audio channel signal and the second encoding parameter average of the audio channel signal.

Abstract: An audio file playing method and an apparatus are disclosed and are used to: when an audio file is played, expand a quantity of audio channel signals in the audio file and improve a playing effect of the audio file. The method is as follows: after the audio file is obtained, determining, whether the audio file includes an audio channel signal that can be played by the mobile device; if the audio file includes the audio channel signal that can be played by the mobile device, directly playing the audio channel signal. Therefore, when multiple mobile devices are used to play a same audio file, the mobile devices can avoid performing a same operation, thereby increasing a quantity of audio channels of the audio file, expanding a sound field of the audio file, and improving a playing effect of the audio file.

Abstract: A method for parametric spatial audio coding of a multi-channel audio signal comprising a plurality of audio channel signals is provided, the method comprising: calculating at least two different spatial coding parameters for an audio channel signal of the plurality of audio channel signals, selecting at least one spatial coding parameter of the at least two different spatial coding parameters associated with the audio channel signal on the basis of the values of the calculated spatial coding parameters; including a quantized representation of the selected spatial coding parameter into a parameter section of an audio bitstream; and setting a parameter type flag in the parameter section of the audio bitstream indicating the type of the selected spatial coding parameter being included into the audio bitstream.

Abstract: The present invention discloses a data storage space processing method and processing system, and a data storage server. The data storage space processing method includes: dividing a disk and memory resource into tablets; dividing memory space of a tablet into different logical objects; and dividing, according to a fixed size, disk space of the tablet into multiple data blocks that are of a same size. According to the data storage space processing system and method provided in embodiments of the present invention, a disk and memory resource on a storage server is divided into independent tablets, and the tablets are used as basic service resource allocating and managing units, which can implement multiplexing of a single-node resource on multiple services. Besides, by using hybrid indexing and associated write combining and block recycling technologies, random write IOPS of a system is improved, and index memory space can also be significantly saved.

Abstract: The present invention provides methods of assessing an individual subject's risk of developing different types of cancer, comprising calculating a genetic risk score (GRS) for the subject.

Abstract: A voice quality enhancement (VQE) detector for a network element receiving an audio signal from a previous network element of a network, wherein said voice quality enhancement detector is adapted: to perform a voice quality enhancement detection based on the received audio signal, wherein said voice quality enhancement detection comprises detecting that at least one voice quality enhancement function, VQEE comprising of a noise cancellation or an echo cancellation function using a Gaussian Mixture Model was applied to the received audio signal by at least one previous network element of the network; and to control a voice quality enhancement processing of the received audio signal depending on the detection result.

Abstract: Methods and devices for a low complex inter-channel difference estimation are provided. A method for the estimation of inter-channel differences (ICDs), comprises applying a transformation from a time domain to a frequency domain to a plurality of audio channel signals, calculating a plurality of ICD values for the ICDs between at least one of the plurality of audio channel signals and a reference audio channel signal over a predetermined frequency range, each ICD value being calculated over a portion of the predetermined frequency range, calculating, for each of the plurality of ICD values, a weighted ICD value by multiplying each of the plurality of ICD values with a corresponding frequency-dependent weighting factor, and calculating an ICD range value for the predetermined frequency range by adding the plurality of weighted ICD values.

Abstract: The present invention provides a method of identifying a subject as having an increased risk of having or developing aggressive prostate cancer, comprising detecting in the subject the presence of various genetic markers associated with an increased risk of having or developing aggressive prostate cancer.

Abstract: Methods and devices for a low complex inter-channel difference estimation are provided. A method for the estimation of inter-channel differences (ICDs), comprises applying a transformation from a time domain to a frequency domain to a plurality of audio channel signals, calculating a plurality of ICD values for the ICDs between at least one of the plurality of audio channel signals and a reference audio channel signal over a predetermined frequency range, each ICD value being calculated over a portion of the predetermined frequency range, calculating, for each of the plurality of ICD values, a weighted ICD value by multiplying each of the plurality of ICD values with a corresponding frequency-dependent weighting factor, and calculating an ICD range value for the predetermined frequency range by adding the plurality of weighted ICD values.

Abstract: A pitch detection method and apparatus are disclosed. The method includes: performing pitch detection on an input signal in a signal domain, and obtaining a candidate pitch; performing linear prediction (LP) on the input signal, and obtaining an LP residual signal; setting a candidate pitch range that includes the candidate pitch; searching the candidate pitch range for the LP residual signal, and obtaining a selected pitch.

Abstract: The invention relates to an audio signal synthesizer, the audio signal synthesizer comprises a transformer for transforming the down-mix audio signal into frequency domain to obtain a transformed audio signal; a signal generator for generating a first auxiliary signal, for generating a second auxiliary signal, and for generating a third auxiliary signal upon the basis of the transformed audio signal; a de-correlator for generating a first de-correlated signal, and for generating a second de-correlated signal from the third auxiliary signal, the first de-correlated signal and the second de-correlated signal being at least partly de-correlated; and a combiner for combining the first auxiliary signal with the first de-correlated signal to obtain a first audio signal, and for combining the second auxiliary signal with the second de-correlated signal to obtain the second audio signal, the first audio signal and the second audio signal forming the multi-channel audio signal.

Abstract: The present invention discloses a data storage space processing method and processing system, and a data storage server. The data storage space processing method includes: dividing a disk and memory resource into tablets; dividing memory space of a tablet into different logical objects; and dividing, according to a fixed size, disk space of the tablet into multiple data blocks that are of a same size. According to the data storage space processing system and method provided in embodiments of the present invention, a disk and memory resource on a storage server is divided into independent tablets, and the tablets are used as basic service resource allocating and managing units, which can implement multiplexing of a single-node resource on multiple services. Besides, by using hybrid indexing and associated write combining and block recycling technologies, random write IOPS of a system is improved, and index memory space can also be significantly saved.

Abstract: The present invention, which is characterized by the employment of blowing agents comprising fluorinated ethers with a boiling point in the range of from about 0 DEG C to 75° C., pertains to a composition of microcellular polyurethane, a method for preparing the same, and its use in manufacturing shoe materials. Compared to shoe soles made from traditional microcellular polyurethane, in particular those made using 1,1,1,2-tetrafluoroethane (HFC 134a) as the blowing agent, the polyurethane shoe soles prepared according to the present invention exhibit similar shrinkage characteristics, and their linear shrinkage is compatible with the current processing conditions, thus can replace traditional blowing systems comprising 1,1,1,2-tetrafluoroethane (HFC 134a) in shoe manufacturing without the need of changing molds. On the premise of being more environmental-friendly, the present invention also effectively saves production cost for shoe manufacturers.

Abstract: Methods of increasing the yield in plant expression of recombinant proteins comprising engineering glycosylation sites into cloned genes or cDNAs for proteins using codons that drive post-translational modifications in plants and engineering the cloned genes or cDNAs to contain a plant secretory signal sequence that targets the gene products (protein) for secretion are present. The methods result in increased recombinant glycosylated protein yields. Proteins produced according to these methods are also present.

Abstract: Methods of increasing the yield in plant expression of recombinant proteins comprising engineering glycosylation sites into cloned genes or cDNAs for proteins using codons that drive post-translational modifications in plants; and engineering the cloned genes or cDNAs to contain a plant secretory signal sequence that targets the gene products (protein) for secretion. The methods result in increased recombinant glycosylated protein yields. Proteins produced according to these methods are disclosed.

Abstract: The invention relates to a method for determining an encoding parameter for an audio channel signal of a multi-channel audio signal, the method comprising: determining a frequency transform of the audio channel signal; determining a frequency transform of a reference audio signal; determining inter channel differences for at least each frequency sub-band of a subset of frequency sub-bands, each inter channel difference indicating a phase difference or time difference between a band-limited signal portion of the audio channel signal and a band-limited signal portion of the reference audio signal in the respective frequency sub-band the inter-channel difference is associated to; determining a first average based on positive values of the inter-channel differences and determining a second average based on negative values of the inter-channel differences; and determining the encoding parameter based on the first average and on the second average.